Results 151 to 160 of about 2,839 (171)
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Use of caproic and cyclohexanecarboxylic acids for determining benzoic and sorbic acids
Pharmaceutical Chemistry Journal, 2013The possibility of using caproic and cyclohexanecarboxylic acids for determining sorbic and benzoic acids, respectively, was studied. The presence of double bonds in sorbic and benzoic acids decreased significantly their retention times compared with those of their saturated analogs (caproic and cyclohexanecarboxylic acids) on chromatography columns ...
A. S. Osipov, E. B. Nechaeva
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Drug Metabolism and Disposition, 1992
The pharmacokinetics of valproic acid (VPA) and its structural analogs cyclohexanecarboxylic acid (CCA) and 1-methyl-1-cyclohexanecarboxylic acid (MCCA) were examined in bile-exteriorized rats. A 0.52 mmol/kg dose (equivalent to 75 mg/kg VPA) of test compound (N = 4 rats per compound) was administered as an intravenous bolus.
M J, Liu, K L, Brouwer, G M, Pollack
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The pharmacokinetics of valproic acid (VPA) and its structural analogs cyclohexanecarboxylic acid (CCA) and 1-methyl-1-cyclohexanecarboxylic acid (MCCA) were examined in bile-exteriorized rats. A 0.52 mmol/kg dose (equivalent to 75 mg/kg VPA) of test compound (N = 4 rats per compound) was administered as an intravenous bolus.
M J, Liu, K L, Brouwer, G M, Pollack
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The Metabolism of Cyclohexanecarboxylic Acid in the Isolated Perfused Rat Liver
Xenobiotica, 19771. Cyclohexanecarboxylic acid in isolated perfused rat livers was eliminated from the perfusion system by a first-order process. 2. After 6 h, 16% was excreted in bile as cyclohexylcarbonyl beta-D-glucuronide. The remainder was present in the perfusate as unchanged cyclohexanecarboxylic acid (10%), hippuric acid (50%), hexahydrohippuric acid (2%), 3,4 ...
D, Brewster, R S, Jones, D V, Parke
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ChemInform Abstract: Spirocyclic Dipeptides of 1‐Amino‐1‐cyclohexanecarboxylic Acid.
ChemInform, 1994AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
J. VINSOVA, K. KOSAR, E. KASAFIREK
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Stereochemistry of cis-2-hydroxy-2-phenyl-cyclohexanecarboxylic acid (cicloxilic acid).
Arzneimittel-Forschung, 1979The configuration of cis-2-hydroxy-2-phenyl-cyclohexanecarboxilic acid (cicloxilic acid) was deduced by comparing its NMR and IR spectra with those of its diastereoisomer and of their respective analogs, the 1-hydroxy(bicyclohexyl)-2-carboxylic acids. The diastereoisomer was prepared by converting cicloxilic acid to the corresponding 2-chloro-2-phenyl ...
L, Turbanti, G, Cebai, G, Ceccarelli
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Recueil des Travaux Chimiques des Pays-Bas, 1966
AbstractA description is given of the synthesis of dimeric α‐nitrosocyclohexanecarboxylic acid (III). This acid provides the first example of the hitherto unknown class of α‐nitrosocarboxylic acids. It is shown that III is not an intermediate in the nitrosodecarboxylation of cyclohexanecarboxylic acid to caprolactam.
E. F. J. Duynstee, M. E. A. H. Mevis
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AbstractA description is given of the synthesis of dimeric α‐nitrosocyclohexanecarboxylic acid (III). This acid provides the first example of the hitherto unknown class of α‐nitrosocarboxylic acids. It is shown that III is not an intermediate in the nitrosodecarboxylation of cyclohexanecarboxylic acid to caprolactam.
E. F. J. Duynstee, M. E. A. H. Mevis
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Tetrahedron: Asymmetry, 2001
Abstract Stereoselective synthesis of the title compounds was performed. The relative configuration of methyl t-4-(tert-butoxycarbonylamino)-c-3-hydroxy-r-1-cyclohexanecarboxylate and methyl trans-4-(tert-butoxycarbonylamino)-3-oxo-r-1-cyclohexanecarboxylate was confirmed by X-ray diffraction methods.
Krzysztof Krajewski +2 more
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Abstract Stereoselective synthesis of the title compounds was performed. The relative configuration of methyl t-4-(tert-butoxycarbonylamino)-c-3-hydroxy-r-1-cyclohexanecarboxylate and methyl trans-4-(tert-butoxycarbonylamino)-3-oxo-r-1-cyclohexanecarboxylate was confirmed by X-ray diffraction methods.
Krzysztof Krajewski +2 more
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Conformational Analysis of IR Spectra of Alkyl and Fluoroalkyl Cyclohexanecarboxylic Acids
Journal of Structural Chemistry, 2002IR spectra were simulated for a series of alkyl and fluoroalkyl cyclohexanecarboxylic acids, whose experimental spectra have been previously recorded in the temperature range 77–500 K. The simulation was performed taking into account the conformational mobility of the molecules and a decrease in the hydrogen‐bond energy of H‐complexes during heating ...
L. M. Babkov +2 more
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Diversions of the Shikimate Pathway — The Biosynthesis of Cyclohexanecarboxylic Acid
1992The shikimic acid pathway1 has evolved in plants and microorganisms to provide for the synthesis of the aromatic amino acids, phenylalanine, tyrosine and tryptophan, as well as a number of other essential aromatic compounds, e.g., jo-aminobenzoic acid, the precursor of folic acid, or]D-hydroxybenzoic acid, the precursor of ubiquinone.
H. G. Floss +8 more
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On the nitration of cyclohexanecarboxylic acid to caprolactam
Recueil des Travaux Chimiques des Pays-Bas, 1962J. A. Bigot +2 more
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