Results 191 to 200 of about 6,586 (225)
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The metabolism of cyclohexanecarboxylic acid and 3-cyclohexenecarboxylic acid by Pseudomonas putida
Canadian Journal of Microbiology, 1982A strain of Pseudomonas putida grew rapidly on cyclohexanecarboxylic acid as a sole source of carbon. A CoA-mediated β-oxidation pathway was induced for the metabolism of the compound. The organism could not utilize 3-cyclohexenecarboxylic acid as a sole source of carbon for growth, but cells grown on gluconate in the presence of 3 ...
Blakley, E. R., Papish, B.
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Biosynthesis of phoslactomycins: cyclohexanecarboxylic acid as the starter unit
Tetrahedron, 2003Abstract Phoslactomycins (PLMs) A–F, produced by actinomycetes are polyketide-type antibiotics derived from a hydroxycyclohexanecarboxylic acid or a cyclohexanecarboxylic acid starter unit. Feeding experiments with [2-13C]shikimic acid indicated that the C-18 carbon of PLMs comes from C-5 of shikimate.
Hiroyuki Osada+3 more
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Epilepsia, 1994
Summary: We examined the pharmacodynamics of valproate (VPA) and three structural analogues, octanoic acid (OA), cyclohexanecarboxylic acid (CCA), and 1‐methyl‐1‐cyclohexanecarboxylic acid (MCCA) in rats. A pentylenetetrazol (PTZ) infusion seizure model was used to determine threshold convulsive doses of PTZ; the increase in PTZ threshold dose after ...
Mei-jen Liu, Gary M. Pollack
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Summary: We examined the pharmacodynamics of valproate (VPA) and three structural analogues, octanoic acid (OA), cyclohexanecarboxylic acid (CCA), and 1‐methyl‐1‐cyclohexanecarboxylic acid (MCCA) in rats. A pentylenetetrazol (PTZ) infusion seizure model was used to determine threshold convulsive doses of PTZ; the increase in PTZ threshold dose after ...
Mei-jen Liu, Gary M. Pollack
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Kinetics and mechanism of coupled synthesis of cyclohexanecarboxylic acid
Russian Journal of Physical Chemistry A, 2015The effect of the nature of the anion in a palladium salt on a coupled process involving the oxidation of CO and hydrocarboxylation of cyclohexene in the PdX2-CuBr2-THF-H2O system was studied. The kinetics was investigated under the steady-state conditions.
O. N. Temkin+9 more
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Molecular and Cellular Biochemistry, 1985
The ability to convert cyclohexanecarboxylic acid to hippuric acid has been studied in liver from guinea pigs, rabbits, rats and mice using a gas chromatographic - mass spectrometric method employing selected ion monitoring. Guinea pig liver showed the highest activity, giving values double of those found in rabbit liver and five times those in rat ...
Asbjørn Svardal, Ronald R. Scheline
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The ability to convert cyclohexanecarboxylic acid to hippuric acid has been studied in liver from guinea pigs, rabbits, rats and mice using a gas chromatographic - mass spectrometric method employing selected ion monitoring. Guinea pig liver showed the highest activity, giving values double of those found in rabbit liver and five times those in rat ...
Asbjørn Svardal, Ronald R. Scheline
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Use of caproic and cyclohexanecarboxylic acids for determining benzoic and sorbic acids
Pharmaceutical Chemistry Journal, 2013The possibility of using caproic and cyclohexanecarboxylic acids for determining sorbic and benzoic acids, respectively, was studied. The presence of double bonds in sorbic and benzoic acids decreased significantly their retention times compared with those of their saturated analogs (caproic and cyclohexanecarboxylic acids) on chromatography columns ...
E. B. Nechaeva, A. S. Osipov
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Journal of Hazardous Materials, 2021
Degradation kinetics, by-products identification and pathways of a model naphthenic acid, cyclohexanecarboxylic acid (CHA), by the UV/Chlorine process were investigated in this study. Mathematical modeling indicated that the initial CHA decay rate increased rapidly with the chlorine dose when the chlorine dose was lower than 45 mg/L and decreased with ...
Mohamed Gamal El-Din+5 more
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Degradation kinetics, by-products identification and pathways of a model naphthenic acid, cyclohexanecarboxylic acid (CHA), by the UV/Chlorine process were investigated in this study. Mathematical modeling indicated that the initial CHA decay rate increased rapidly with the chlorine dose when the chlorine dose was lower than 45 mg/L and decreased with ...
Mohamed Gamal El-Din+5 more
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Diversions of the Shikimate Pathway — The Biosynthesis of Cyclohexanecarboxylic Acid
1992The shikimic acid pathway1 has evolved in plants and microorganisms to provide for the synthesis of the aromatic amino acids, phenylalanine, tyrosine and tryptophan, as well as a number of other essential aromatic compounds, e.g., jo-aminobenzoic acid, the precursor of folic acid, or]D-hydroxybenzoic acid, the precursor of ubiquinone.
Karl Poralla+17 more
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Canadian Journal of Microbiology, 1982
A yeast capable of utilizing cyclohexanecarboxylic acid as sole carbon and energy source, strain KUY-6A, was isolated from soil by enrichment cultures. Taxonomical studies indicated that strain KUY-6A was Trichosporon cutaneum. Strain KUY-6A grew on a number of carboxylic acids.
Tai Tokuyama+4 more
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A yeast capable of utilizing cyclohexanecarboxylic acid as sole carbon and energy source, strain KUY-6A, was isolated from soil by enrichment cultures. Taxonomical studies indicated that strain KUY-6A was Trichosporon cutaneum. Strain KUY-6A grew on a number of carboxylic acids.
Tai Tokuyama+4 more
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Drug Metabolism and Disposition, 1992
The pharmacokinetics of valproic acid (VPA) and its structural analogs cyclohexanecarboxylic acid (CCA) and 1-methyl-1-cyclohexanecarboxylic acid (MCCA) were examined in bile-exteriorized rats. A 0.52 mmol/kg dose (equivalent to 75 mg/kg VPA) of test compound (N = 4 rats per compound) was administered as an intravenous bolus.
M J, Liu, K L, Brouwer, G M, Pollack
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The pharmacokinetics of valproic acid (VPA) and its structural analogs cyclohexanecarboxylic acid (CCA) and 1-methyl-1-cyclohexanecarboxylic acid (MCCA) were examined in bile-exteriorized rats. A 0.52 mmol/kg dose (equivalent to 75 mg/kg VPA) of test compound (N = 4 rats per compound) was administered as an intravenous bolus.
M J, Liu, K L, Brouwer, G M, Pollack
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