Results 101 to 110 of about 2,296 (262)
Chemistry – A European Journal, EarlyView.Efficient cationic gold(I)‐catalyzed intermolecular cyclopropanation of 7‐alkynylnorbornadiene derivatives has been developed. This methodology offers the synthesis of a new class of norbornene derivatives in high yield with excellent diastereoselectivity.
Kento Ishida +3 more
wiley +1 more source
Discovery of Disubstituted Cyclohexanes as a New Class of CC Chemokine Receptor 2 Antagonists
, 2016 We describe the design, synthesis, and evaluation of novel disubstituted cyclohexanes as potent CCR2 antagonists. Exploratory SAR studies led to the cis-disubstituted derivative 22, which displayed excellent binding affinity for CCR2 (binding IC50 = 5.1 ...
Robert J. Cherney (2354959) +13 more
core +1 more source
Organocatalytic Formal (3+2+1)‐Cycloaddition of Allenoates, Michael Acceptors, and Carbaldehydes
Chemistry – A European Journal, EarlyView.The use of secondary amine Lewis base organocatalysts allows for the unprecedented activation of allenoates for formal (3+2+1)‐cycloadditions with Michael acceptors and aromatic carbaldehydes. ABSTRACT Employing secondary amines as covalently interacting Lewis basic organocatalysts allows for the activation of electron‐deficient allenes (allenoates ...
David Naderer +5 more
wiley +1 more source
International audienceIn this report, we address the challenge of assigning diastereomers for methyl cyclohexanes, particularly those with quaternary centers, which remains nontrivial despite modern NMR techniques.
Cordier, Marie +3 more
core +1 more source
, 2015 A series of novel 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes (3a–u) were synthesized from the reaction of aromatic ketones with aromatic aldehydes under mild reaction conditions in good yields.
Hayreddin Gezegen (539127) +1 more
core +1 more source
Germylium Catalyzed Dehydrofluorination Reactions of Fluorinated Alkanes
Chemistry – A European Journal, EarlyView.Dehydrofluorination reactions of fluorinated alkanes catalyzed by germylium ions are reported. Computational studies of the mechanism revealed an E2 type mechanism involving a germane as a base to facilitate olefin formation in competition with an SN2 mechanism for hydrodefluorination.
Julie Borel +3 more
wiley +1 more source
Conformation studies of isomeric 1-acyloxy-2-(4-methoxybenzyl)-cyclohexanes by 1H NMR spectroscopy
, 1982 The conformation of the cyclohexane ring and the p-methoxybenzyl substituent in the series of isomeric 1-acyloxy-2-(4-methoxybenzyl)cyclohexanes was studied by means of 1H NMR spectroscopy.
Zdeněk Wimmer +2 more
core +1 more source
Chemistry – A European Journal, EarlyView.Nitrooxylation—the installation of nitrate esters (–ONO2) has evolved from classical mixed‐acid protocols to catalytic and mechano‐, flow‐, photo‐, and electrochemical strategies. This review delineates ionic and radical manifolds for C–ONO2 bond formation, emphasizing mechanistic control, selected substrate scope, and selectivity.
Jayanta Dey, Dmitry Katayev
wiley +1 more source
Heteroatom‐Doped Graphdiynes and Their Applications in Photo‐/Electro‐Catalytic CO2 Conversion
Carbon Innovation, EarlyView.This review highlights the versatile role of doped graphdiyne (GDY) in boosting CO2 conversion, where metal and non‐metal doping simultaneously tune the electronic structure, create abundant active sites, and improve charge separation, light harvesting, and CO2 adsorption.
Fangzhou Yang +3 more
wiley +1 more source
ChemSusChem, Volume 18, Issue 6, March 15, 2025.Novel organic solvents with an unmodified carbohydrate core were synthesised both from D‐xylose and directly from biomass and were successfully used as reaction media for lipase biocatalysts to synthesise aliphatic and aromatic polyesters. Abstract The use of organic solvents in academic research and industry applications is facing increasing ...
Anastasia O. Komarova +8 more
wiley +1 more source