Results 271 to 280 of about 221,688 (338)

Parallel In Vitro and In Silico Studies of the Anti-Inflammatory Activity of Bioactive Compounds Found in Different Ethanolic Extracts of Bracts from <i>B. x buttiana</i> (var. Rose): A Comparative Analysis. [PDF]

Pharmaceuticals (Basel)
Castañeda-Corral G, Cedillo-Cortezano M, Petricevich VL.   +2 more
europepmc   +1 more source

Induction of cyclooxygenase‐2 expression in human myometrial smooth muscle cells by interleukin‐1β: involvement of p38 mitogen‐activated protein kinase

, 1999
Simon Bartlett, Robert Sawdy, Giovanni E. Mann   +2 more
openalex   +2 more sources

Cuproptosis Signature Would Reveal the Acute‐Remitting Pattern in Patients with Neuromyelitis Optica Spectrum Disorder

Advanced Science, EarlyView.
Neuromyelitis optica spectrum disorder (NMOSD) has distinct acute‐remitting courses but lacks biomarkers for predicting relapse. Recent studies found cuproptosis‐related genes affect its course, and a model built accordingly can predict relapse to aid intervention.
Peidong Liu, Ruoyu Li, Xinlin Wang, Hui Li, Huiru Hu, Ang Shen, Wenping Zhu, Jiali Pan, Yanmeng Xing, Weiming Xia, Henan Jiao, Di Chen, Lixin Wu, Li Liu, Ju Liu, Bin Yu, Xianzhi Liu, Hongbo Liu   +17 more
wiley   +1 more source

Dysregulation of Arachidonic Acid Metabolism Drives Inflammatory Lipid Production in Localized Provoked Vulvodynia. [PDF]

Nutrients
Fischer SA, Oladele O, Mahamed Z, Chrysilla E, Baumer A, Bekauri T, Maddipati KR, Love T, Linder M, Falsetta M.   +9 more
europepmc   +1 more source

Profile of JTE-522 as a Human Cyclooxygenase-2 Inhibitor

, 1998
Korekiyo Wakitani, Toyomichi Nanayama, M. Masaki, Mutsuyoshi Matsushita   +3 more
openalex   +1 more source

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

Advanced Science, EarlyView.
The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou   +14 more
wiley   +1 more source

Fuzheng Xuanfei Huashi prescription suppresses inflammation in lipopolysaccharide-induced lung injury in mice toll-like recptor 4/nuclear transcription factor κB and cyclooxygenase-2/prostaglandin E2 pathway. [PDF]

J Tradit Chin Med
Haiyang H, Shumin Z, Shaowen Z, Ying L, Shaozhen H, Jie G, Jianzhao OU, Mingguo D, Weimin N.   +8 more
europepmc   +1 more source

NIR Driven Pd/Cerium Oxide Nano‐Heterojunction for Enhanced Salvaging Sepsis Induced Acute Liver Injury via Reprogramming Redox Homeostasis in Synergy with Inducing Autophagy

Advanced Science, EarlyView.
In vivo SALI therapy is achieved by scavenging intracellular ROS levels, downregulating inflammatory factors expression levels, inducing macrophage M2 directional polarization, and activating Keap1/Nrf‐2/HO‐1 pathway to reprogram redox homeostasis, induce cellular autophagy, reduce systemic inflammation, and promote liver tissue repair. Abstract Sepsis
Tao Qin, Lian Qin, Yang Zhao, Yin Chen, Qianyue Liu, Xiaoguang Lin, Yongfeng Lan, Yaohui Huang, Yan Liu, Ke Zhang, Lifan Pan, Jiaxiao Li, Kunpeng Duan, Hao Liang, Mingjing Yin, Guiyang Fan, Lian Liu, Yu Deng, Lin Liao, Danke Su, Ming Gao, Junyu Lu   +21 more
wiley   +1 more source

Effects of increasing the dietary contents of metabolizable energy and protein during the peripartum period on mammary gland development in Sistani goats. [PDF]

Sci Rep
Dirandeh E, Ansari-Pirsaraei Z, Teimouri A, Dadashpour N, Thatcher WW.   +4 more
europepmc   +1 more source

Inhibition of UBE2C Promotes Parkin‐Mediated K63‐Linked Ubiquitination of TOP2A to Induce Senescence and Increase Sensitivity of Doxorubicin in Breast Cancer

Advanced Science, EarlyView.
In the study, UBE2C was found to be significantly overexpressed in breast cancer and transcriptionally regulated by FOXM1. Inhibition of UBE2C suppressed proliferation, induced senescence, and sensitized breast cancer cells to doxorubicin. Mechanistically, UBE2C inhibition promoted Parkin‐mediated K63‐linked ubiquitination of TOP2A.
Yihui Yang, Wan Li, Hong Yang, Fang Xu, Sen Zhang, Wanxin Cao, Xiaoxue Li, Xu Zhang, Xiangyin Chi, Hongquan Wang, Guanhua Du, Yumin Wang, Jinhua Wang   +12 more
wiley   +1 more source