Results 201 to 210 of about 190,703 (326)

2D interaction of compound 6e (left) and indomethacin drug (right) within the active site of cyclooxygenase-1 (COX-1) (PDB ID: 1EQG).

Yasser Hussein Issa Mohammed (17140711), Ahmed Hassen Shntaif (22320292), Saad Alghamdi (362506), Ahd A. Mansour (21660692), Naeem F. Qusty (15416890), Azhar S. Sindi (13259916), Ahmad O. Babalghith (15279713), Ghazi A. Bamagous (22320295), Eman Adnan Abu-Seer (22320298)   +8 more
openalex   +1 more source

Anti-chemorepulsive Effects of Vascular Endothelial Growth Factor and Placental Growth Factor-2 in Dorsal Root Ganglion Neurons Are Mediated via Neuropilin-1 and Cyclooxygenase-derived Prostanoid Production [PDF]

, 2004
Lili Cheng, Haiyan Jia, Marianne Löhr, Azadeh Bagherzadeh, David Holmes, David L. Selwood, Ian Zachary   +6 more
openalex   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Microglial cyclooxygenase-1 modulates cerebral capillary basal tone in vivo in mice. [PDF]

Nat Commun
Mills WA, Savory NA, Lopez-Ortiz AO, Lentferink DH, González Ibáñez F, Agochi P, Rastegar E, Gupta A, Gupta D, Suram A, Isakson BE, Tremblay MÈ, Eyo UB.   +12 more
europepmc   +1 more source

Inhibition of Both Cyclooxygenase-1 and -2 Promotes Epicutaneous Th2 and Th17 Sensitization and Allergic Airway Inflammation on Subsequent Airway Exposure to Protease Allergen in Mice.

Int Arch Allergy Immunol, 2021
Suchiva P, Takai T, Kamijo S, Maruyama N, Yokomizo T, Sugimoto Y, Okumura K, Ikeda S, Ogawa H.   +8 more
europepmc   +1 more source

Low-Dose Aspirin Treatment Attenuates Male Rat Salt-Sensitive Hypertension via Platelet Cyclooxygenase 1 and Complement Cascade Pathway. [PDF]

J Am Heart Assoc, 2020
Jiang X, Liu X, Liu X, Wu X, Jose PA, Liu M, Yang Z.   +6 more
europepmc   +1 more source

Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential cyclooxygenase (COX-1, COX-2) inhibitors

, 2014
Jagdeep Grover, Vivek Kumar, Vikram Singh, Khemraj Bairwa, M. Elizabeth Sobhia, Sanjay M. Jachak   +5 more
openalex   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Cyclooxygenase-1 and cyclooxygenase-2 densities measured using positron emission tomography are not altered in the brains of individuals with stable multiple sclerosis. [PDF]

J Cereb Blood Flow Metab
Tang S, Harrison DM, Bardhoshi A, Cureton R, Yan X, Parcon PA, Morse CL, Ecker C, Choi S, Pike VW, Innis RB, Zanotti-Fregonara P.   +11 more
europepmc   +1 more source

Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells. [PDF]

Sci Rep, 2020
Huang K, Masuda A, Chen G, Bushra S, Kamon M, Araki T, Kinoshita M, Ohkawara B, Ito M, Ohno K.   +9 more
europepmc   +1 more source