Results 251 to 260 of about 21,811,854 (372)

Aberrantly activated Cox-2 and Wnt signaling interact to maintain cancer stem cells in glioblastoma [PDF]

open access: yes, 2017
Das, Sunit   +9 more
core   +3 more sources

SCORT–Cas13d Nanotherapy Precisely Targets the ‘Undruggable’ Transcription Factor HoxB13 in Metastatic Prostate Cancer In Vivo

open access: yesAdvanced Science, EarlyView.
SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui   +15 more
wiley   +1 more source

Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis

open access: yesEBioMedicine, 2014
T. Hannan   +15 more
semanticscholar   +1 more source

Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice. [PDF]

open access: yesJCI Insight
Aikawa S   +20 more
europepmc   +1 more source

Bioengineered Tumor‐Derived Extracellular Vehicles Suppressed Colorectal Cancer Liver Metastasis and Bevacizumab Resistance

open access: yesAdvanced Science, EarlyView.
The upregulated CCL24 in CRC liver metastasis promotes the formation of inflammatory tumor‐associated fibroblast subsets and induces resistance to bevacizumab therapy. Downregulation of CCL24 significantly increased sensitivity to antiangiogenic therapy in CRC mouse model. Hence, a novel therapeutic target is identified for patients with CRC with liver
Junjiang Wang   +7 more
wiley   +1 more source

Regulation of cyclooxygenase 2 expression in hepatocytes by CCAAT/enhancer-binding proteins [PDF]

open access: bronze, 2000
Nuria A. Callejas   +4 more
openalex   +1 more source

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1994
J. Masferrer   +7 more
semanticscholar   +1 more source

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