Results 291 to 300 of about 21,811,854 (372)

Effects of Etlingera elatior flower extract on cyclooxygenase-2 expression in the gingival epithelium in a diabetic periodontitis rat model. [PDF]

J Taibah Univ Med Sci
Syaify A, Sari R, Alhasyimi AA.
europepmc   +1 more source

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Advanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen   +10 more
wiley   +1 more source

INDUCTION OF CYCLOOXYGENASE-2 ACTIVITY IN HUMAN OSTEOARTHRITIS-AFFECTED CARTILAGE: INFLUENCE OF NITRIC OXIDE

, 1997
AR Amin, Mukundan Attur, RN Patel, GD Thakker, P B MARSHALL, John Rediske, SA Stuchin, Steven B. Abramson   +7 more
openalex   +1 more source

Shikonin induces the apoptosis and pyroptosis of EGFR-T790M-mutant drug-resistant non-small cell lung cancer cells via the degradation of cyclooxygenase-2. [PDF]

Eur J Med Res
Cao S, Li H, Ye X, Xing X, Xie Y, Zeng X, Liu H, Zhong X, Yang X, Xing W, Zhu C, Wu X.   +11 more
europepmc   +1 more source

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang, Kexin He, Ruixue Huo, Weihan Li, Shan Zhang, Lu‐Ju Jiang, Hao Wu, Minhao Yu, Shu‐Heng Jiang, Junli Xue   +9 more
wiley   +1 more source

Renal effects of selective cyclooxygenase-2 inhibitor anti-inflammatory drugs: A systematic review and meta-analysis. [PDF]

Explor Res Clin Soc Pharm
Biase TMMA, Rocha JGM, Silva MT, Ribeiro-Vaz I, Galvão TF.   +4 more
europepmc   +1 more source

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Advanced Science, EarlyView.
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan‐Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar‐Haim, Orit Redy‐Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud   +12 more
wiley   +1 more source

THE INDUCTION OF CYCLOOXYGENASE-2 (COX-2) IN PULMONARY INTRAVASCULAR PMNs ACCOUNTS FOR THROMBOXANE SYNTHESIS IN ENDOTOXIN-PRIMED RAT LUNGS

, 1995
Masayuki Chida, Voelkel Nf, Westcott JY, Shigehiro Ono, Tatsuo Tanita, S Fujimura   +5 more
openalex   +1 more source

Fuzheng Xuanfei Huashi prescription suppresses inflammation in lipopolysaccharide-induced lung injury in mice toll-like recptor 4/nuclear transcription factor κB and cyclooxygenase-2/prostaglandin E2 pathway. [PDF]

J Tradit Chin Med
Haiyang H, Shumin Z, Shaowen Z, Ying L, Shaozhen H, Jie G, Jianzhao OU, Mingguo D, Weimin N.   +8 more
europepmc   +1 more source