Results 71 to 80 of about 1,126,910 (189)

Reduction in cancer risk by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors

Journal of Experimental Pharmacology, 2012
Randall E Harris,1 Joanne Beebe,1 Galal A Alshafie21College of Medicine and College of Public Health, 2College of Pharmacy, The Ohio State University, Columbus, Ohio, USAAbstract: We conducted a series of epidemiologic studies to evaluate the ...
Harris RE, Beebe J, Alshafie GA
doaj  

Design and Synthesis of Novel 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives as Cyclooxygenase-2 Inhibitors with Anti-inflammatory and Antioxidant activity in LPS-stimulated RAW264.7 Macrophages. [PDF]

Bioorg Chem, 2022
Hamoud MMS, Osman NA, Rezq S, A A Abd El-Wahab H, E A Hassan A, Abdel-Fattah HA, Romero DG, Ghanim AM.   +7 more
europepmc   +1 more source

Inhibitors of cyclooxygenase-2-dependent modulation of functional characteristics of leukocytes

RUDN Journal of Medicine, 2009
Cyclooxygenase (COX), the primary enzyme responsible for the synthesis of prostanoids, exists in at least 2 isoforms. COX-2 has been suggested to be the isoform primarily responsible for synthesis of prostaglandins (PGs) in the context of inflammation ...
A V Pasechnik, O N Semochkina, E G Moiseeva   +2 more
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Editorial: Risk of cardiovascular events and cyclooxygenase-2 inhibitors ||FREE PAPER||

Vascular Health and Risk Management, 2006
Reza TabrizchiDivision of Basic Medical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St John’s, NL, CanadaSelective cyclooxygenase-2 (Cox-2) inhibitors have been at the centre of public attention since the revelation that the
Reza Tabrizchi
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Pulmonaria obscura and Pulmonaria officinalis Extracts as Mitigators of Peroxynitrite-Induced Oxidative Stress and Cyclooxygenase-2 Inhibitors-In Vitro and In Silico Studies. [PDF]

Molecules, 2021
Krzyżanowska-Kowalczyk J, Kowalczyk M, Ponczek MB, Pecio Ł, Nowak P, Kolodziejczyk-Czepas J.   +5 more
europepmc   +1 more source

Perioperative nonsteroidal anti-inflammatory drugs and the risk for anastomotic leakage in patients undergoing major gastrointestinal surgery: a retrospective cohort study

BMC Anesthesiology
Background Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for postoperative pain management; however, their safety in patients at risk for anastomotic leakage remains uncertain.
Haoyun Zhang, Feng Zhao, Ting Zhang, Likai Shi, Shiyi Han, Xuecai Lv, Hao Li, Jingsheng Lou, Jiangbei Cao, Weidong Mi, Yanhong Liu   +10 more
doaj   +1 more source

Design, synthesis, biological assessment and in silico ADME prediction of new 2-(4-(methylsulfonyl) phenyl) benzimidazoles as selective cyclooxygenase-2 inhibitors. [PDF]

RSC Adv, 2021
Badawy MAS, Abdelall EKA, El-Nahass ES, Abdellatif KRA, Abdel-Rahman HM.   +4 more
europepmc   +1 more source

Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors. [PDF]

ACS Med Chem Lett, 2020
Uddin MJ, Xu S, Crews BC, Aleem AM, Ghebreselasie K, Banerjee S, Marnett LJ.   +6 more
europepmc   +1 more source

Preemptive analgesia using selective cyclooxygenase-2 inhibitors alleviates postoperative pain in patients undergoing total knee arthroplasty: A protocol for PRISMA guided meta-analysis of randomized controlled trials. [PDF]

Medicine (Baltimore), 2021
Wang C, Fu H, Wang J, Huang F, Cao X.
europepmc   +1 more source

Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors.

Journal of the National Cancer Institute, 2006
S. Grösch, T. Maier, S. Schiffmann, G. Geisslinger   +3 more
semanticscholar   +1 more source