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Physicians' attitudes toward gastroprotective strategies for nonsteroidal anti-inflammatory drug prescription. [PDF]

open access: yesProc (Bayl Univ Med Cent)
Abdeljaleel F   +4 more
europepmc   +1 more source

Cyclooxygenase‐independent actions of cyclooxygenase inhibitors

The FASEB Journal, 2001
Several studies have demonstrated unequivocally that certain nonsteroidal anti-inflammatory drugs (NSAIDs) such as sodium salicylate, sulindac, ibuprofen, and flurbiprofen cause anti-inflammatory and antiproliferative effects independent of cyclooxygenase activity and prostaglandin synthesis inhibition.
Gerd Geisslinger   +2 more
openaire   +4 more sources

Selective Cyclooxygenase Inhibitors: Current Status

Current Drug Discovery Technologies, 2014
For ages aspirin has established its value as an analgesic, anti-inflammatory drug, but in 1938, it was found to be a causative factor of gastric inflammation (ulcer). Later discovered non-steroidal anti-inflammatory drugs (NSAIDs) were found effective as aspirin but failed to overcome the goal of safer aspirin.
Malepati Rajapranathi   +3 more
openaire   +4 more sources

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