Results 311 to 320 of about 112,794 (342)
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Cyclooxygenase-2 Inhibitors in Glioma Therapy
American Journal of Therapeutics, 2004The cyclooxygenase enzyme is a prostaglandin synthase that has two isoforms, cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). Upregulation of the COX-2 isoform in many cancers has led to investigation regarding the potential role of this enzyme in oncogenesis.
Pierre, Giglio, Victor, Levin
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Cyclooxygenase-2 selective inhibitors and the kidney
Current Opinion in Internal Medicine, 2001Cyclooxygenases (COX) are the target of non-steroidal anti-inflammatory drugs (NSAIDs) which exert their therapeutic effect by blocking COX's capacity to metabolize arachidonate to a series of biologically active fatty acids, designated prostaglandins.
M D, Breyer, C, Hao, Z, Qi
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Cyclooxygenase 2 inhibitors: discovery, selectivity and the future
Trends in Pharmacological Sciences, 1999Lawrence J Marnett
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Selective Cyclooxygenase-2 Inhibitors Development in Cardiovascular Medicine
Circulation, 2005Domenico Praticò
exaly
Novel 5-substituted 1H-tetrazoles as cyclooxygenase-2 (COX-2) inhibitors
Bioorganic and Medicinal Chemistry Letters, 2012Sai Kiran Sharma +2 more
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