Results 21 to 30 of about 4,252 (145)

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Diastereoselective Synthesis of Highly Substituted Methylene Cyclobutanes by Pd Catalysis

European Journal of Organic Chemistry, Volume 29, Issue 30, 12 August 2026.
A chemo‐ and diastereoselective palladium‐catalyzed intramolecular coupling/cyclization of borylated 1,5‐dienes, readily accessible by allene allylboration, with iodoarenes enables the synthesis of highly substituted methylene cyclobutanes. The method exhibits broad scope, high functional group tolerance, and complete enantiospecificity.
Jose M. Malga, Martín Fañanás‐Mastral   +1 more
wiley   +1 more source

Effect of Intramolecular Hydrogen Bonds on the Binding Efficiency of Compounds Containing Aminoalcohol‐Based Subunits in Combination with Heterocyclic Groups

European Journal of Organic Chemistry, Volume 29, Issue 29, 7 August 2026.
This study broadens our understanding of the role of intramolecular interactions in molecular recognition and highlights the importance of considering their formation when designing artificial receptors, new drugs, and related systems. Aminoalcohols represent an important class of compounds and serve as building blocks for numerous biologically active ...
Manuel Stapf, Monika Mazik
wiley   +1 more source

Counterion Effects on the Properties and Reactivity of Charged Photoredox Catalysts

ChemPhotoChem, Volume 10, Issue 8, August 2026.
The choice of a counterion for a charged photocatalyst has long been overlooked. In this review, we summarize recent reports on counterion effects in photocatalysis, providing readers with a comprehensive theoretical understanding and synthetic applications for the use of a carefully chosen counterion. Electrostatic interactions represent the strongest
Elina K. Taskinen, Burkhard König
wiley   +1 more source

Uptake and Transport of Monotropein and Monotropein Esters in a Caco‐2/HT29‐MTX‐E12 Co‐Culture Model

Molecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.
Monotropein and its naturally occurring ester derivatives (monotropein‐10‐coumarate and monotropein‐10‐cinnamate) from Gaultheria spp. berries exhibit limited intestinal permeability in a validated Caco‐2:HT29‐MTX‐E12 co‐culture model. Absorption occurs predominantly via passive diffusion, with partial SGLT1‐ and OATP‐mediated uptake contribution for ...
Christian Zielinski, Victor Schmalle, Luise A. Lauer, Tim Hammerschick, Felix Rüttler, Walter Vetter, Jan Frank, Felipe Jiménez‐Aspee   +7 more
wiley   +1 more source

Ectopic Expression of ScALDH21 From a Desert Moss Enhances Cotton Resistance to Verticillium Wilt via the Modulation of Jasmonates and Phenylpropanoid Pathways

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4916-4932, August 2026.
ABSTRACT Biotic stresses, particularly Verticillium wilt (VW), lead to a global decline in cotton yields. Here, we demonstrate that ectopic expression of ScALDH21, a gene from the desiccation‐tolerant moss Syntrichia caninervis Mitt. and absent in angiosperms, enhances cotton's resistance to VW.
Honglan Yang, Xiaoshuang Li, Tohir A. Bozorov, Jianwei Zhang, Aerguli Jiamahate, Dawei Zhang, Jiancheng Wang, Qilin Yang, Zongrang Liu, Dina Mahesati, Haijiang Xu, Shuangxia Jin, Daoyuan Zhang, Yongqiang Dai   +13 more
wiley   +1 more source

Acyclic Hydrocarbon α,ω‐Dienes: From Biomass and Plastic Upcycling to Carbocycles, Precision Polymers, and Cross‐Linked Elastomers

ChemSusChem, Volume 19, Issue 14, 29 July 2026.
Hydrocarbon α,ω‐dienes are mainly produced from steam‐cracking derivatives, but high costs, complexity, and environmental impact limit their use. This review highlights sustainable paths from biomass and plastic upcycling, and surveys catalytic transformations into carbocycles and specialty polymers, emphasizing their role as modular building blocks ...
Rosa Villaccio, Giuseppe Leone
wiley   +1 more source

Synthetic Studies on Cyclopentane Derivatives

Agricultural and Biological Chemistry, 1969
An alternative route to dl-prostaglandin-B1 using the Grignard reaction of 2-(6′-tert-butyloxycarbonylhexyl)-3-methoxy-2-cyclopenten-1-one(XII) with 3-tetrahydropyranyloxy-1-octyne was developed.An easy synthesis of dihydrojasmone was also described.
Junki KATSUBE, Masanao MATSUI
openaire   +3 more sources

Theoretical investigation of atomic oxygen erosion mechanisms of 1,3-didecyl cyclopentane, 1,3-dioctyldodecyl cyclopentane and alkylated cyclopentane

RSC Adv., 2014
Atomic oxygen erosion mechanisms of 1,3-didecyl cyclopentane, 1,3-dioctyldodecyl cyclopentane and alkylated cyclopentane.
Jingyan Nian, Ping Gao, Yongcheng Wang, Zhiguang Guo, Weimin Liu   +4 more
openaire   +1 more source

Epoxide ring-opening approach to the synthesis of diverse trisubstituted cyclopentanes

ARKIVOC, 2016
Evgeni A. Larin, Yuri M. Atroshchenko
doaj   +1 more source