Results 101 to 110 of about 3,458 (212)
, 2009 International audienceWe report a biochemical and structural characterization of domain 2 of the non-structural 5A protein (NS5A) from the JFH1 Hepatitis C virus strain and its interactions with Cyclophilins A and B (CypA and CypB).
Wieruszeski, Jean-Michel +7 more
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The importance of Cyclophilins and Mps1 in cancer [PDF]
, 2022 Hepatic fibrosis is a pathological response to chronic liver injuries such as chronic alcohol consumption, non-alcoholic fatty liver disease (NAFLD) or chronic viral infections.
Simon Serrano, Sonia
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Beyond Hemostasis: Platelet Biomarkers and Vascular‐Immune Crosstalk in Dengue
The FASEB Journal, Volume 40, Issue 12, 30 June 2026.Several biomarkers are associated with platelet activation during dengue virus (DENV) infection. These include serum markers (AST, ALT, ferritin), platelet surface or secreted molecules (P‐selectin, PF4, RANTES, VEGF‐A, CD40L, TREM‐1, TLT‐1), immune and endothelial markers (TREM‐1, Ang‐1, Ang‐2), and viral components such as DENV EIII.
Amanda Beatriz Adriano da Silva‐Alencar +6 more
wiley +1 more source
Maturation-induced conformational changes of HIV-1 capsid protein and identification of two high affinity sites for cyclophilins in the C-terminal domain [PDF]
, 1999 Viral incorporation of cyclophilin A (CyPA) during the assembly of human immunodeficiency virus type-1 (HIV-1) is crucial for efficient viral replication.
Gehring, H, Endrich, M M, Gehrig, P
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Molecular Mechanisms Underlying Root Nodule Formation and Activity
AgronomySymbiotic interactions between legumes and a group of soil bacteria, known as rhizobia, lead to the formation of a specialized organs called root nodules.
Katarzyna Nuc, Przemysław Olejnik
doaj +1 more source
, 2011 The soil nitrogen-fixing bacterium <i>Azotobacter vinelandii</i> possesses two cyclophilins, comprising putative cytoplasmic and periplasmic isoforms, designated as <i>Av</i>PPIB and <i>Av</i>PPIA, respectively.
Evangelia D. Kouri +5 more
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Cyclophilin polymorphism and virus infection
Current Opinion in Virology, 2015 Viruses are obligate intracellular parasites. All stages of their replication cycle depend on support by host-encoded factors. However, sequence variation also exists in host factors mostly in the form of single nucleotide polymorphisms (SNPs). Several coding and non-coding genetic variants in the PPIA gene encoding for CypA have been described, but ...
von Hahn, Thomas, Ciesek, Sandra
openaire +2 more sources
Cyclosporine inhibits a direct interaction between cyclophilins and hepatitis C NS5A.
PLoS ONE, 2010 BackgroundHepatitis C Virus (HCV) infection is a leading indication for liver transplantation. HCV infection reoccurs almost universally post transplant, decreasing both graft longevity and patient survival.
Fiona Fernandes +2 more
doaj +1 more source
Peptidylprolyl Isomerases as In Vivo Carriers for Drugs That Target Various Intracellular Entities
Biomolecules, 2017 Analyses of sequences and structures of the cyclosporine A (CsA)-binding proteins (cyclophilins) and the immunosuppressive macrolide FK506-binding proteins (FKBPs) have revealed that they exhibit peculiar spatial distributions of charges, their overall ...
Andrzej Galat
doaj +1 more source
Cyclophilins and their possible role in the stress response
, 1999 Cyclophilins are proteins which are remarkably conserved through evolution; moreover they have been found in every possible existing organism, which indicates their fundamental importance.
Green, C J, Andreeva, L, Heads, R
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