Results 111 to 120 of about 3,458 (212)

Extracellular cyclophilins contribute to the regulation of inflammatory responses.

, 2005
The main regulators of leukocyte trafficking during inflammatory responses are chemokines. However, another class of recently identified chemotactic agents is extracellular cyclophilins, the proteins mostly known as receptors for the immunosuppressive ...
Okwumabua, I., Constant, S.L., Gwinn, W.M., Arora, K., MacDonald, H.R., Watson, A., Bower, M.A., Bukrinsky, M.I.   +7 more
core  

Cyclophilin inhibitors as antiviral agents

Bioorganic & Medicinal Chemistry Letters, 2013
Cyclophilins (Cyps) are ubiquitous proteins that effect the cis-trans isomerization of Pro amide bonds, and are thus crucial to protein folding. CypA is the most prevalent of the ~19 human Cyps, and plays a crucial role in viral infectivity, most notably for HIV-1 and HCV.
Peel, Michael, Scribner, Andrew
openaire   +2 more sources

SIV replication in human cells

Frontiers in Microbiology, 2012
Current human immunodeficiency virus type 1 (HIV-1) pandemic is believed to originate from cross-species transmission of simian immunodeficiency virus (SIV) into human population.
Hiroaki eTakeuchi, Ryuta eSakuma
doaj   +1 more source

Inhibition of Extracellular Cyclophilins with Cyclosporine Analog and Development of Atherosclerosis in Apolipoprotein E–Deficient Mice s

, 2015
Cyclophilins exert both intracellular and extracellular activi-ties related to immune responses and inflammation, which have been implicated in pathogenesis of atherosclerosis.
Huanhuan L. Cui, Miroslav Malesevic, Ditiatkovski, Michael, Sviridov, Dmitri, Michael Ditiatkovski, Vijaya N. L. V. Neelisetti, Gunter Fischer, Cui, Huanhuan, Michael Bukrinsky, Malesevic, Miroslav, Bukrinsky, Michael I., Dmitri Sviridov, Neelisetti, Vijaya, Fischer, Gunter   +13 more
core  

Protein sequence alignment between lactococcal PpiA protein and related cyclophilins.

, 2012
The sequences of some cyclophilins: Homo sapiens hCyp18 (Accession n° P62937), E. coli PpiA (P0AFL3), S. pneumoniae SlrA (NP_358273), and L. lactis PpiA (from strain IL1403: NP_266521.1 or strain MG1363: YP_001031737.1), are shown. Sequence alignment was
Jean-Jacques Gratadoux (78454), Marie-Pierre Chapot-Chartier (123718), Isabelle Poquet (176780), Alain Guillot (176760), Hervé Ginisty (176777), Nicolas Trémillon (176743), Eric Morello (176746), Laura Monlezun (176769), Daniel Llull (176749), Rabia Mazmouz (176753), Véronique Solé (176773)   +10 more
core   +1 more source

Calmodulin, Cyclophilin, and Cyclosporin A [PDF]

Science, 1986
W N, Hait, M W, Harding, R E, Handschumacher   +2 more
openaire   +2 more sources

Characterization of a new broad spectrum molecules , inhibitors of cyclophilins, on Zika virus and coronavirus replication

, 2021
Au cours des dernières années, l’émergence de nombreux virus (H5N1, SARS, Chikungunya, MERS, Ebola, Zika, SARS-CoV-2) a souvent défrayée la chronique, mettant l’accent sur notre vulnérabilité face aux risques de pandémies, car il n’existe aucun ...
Softic, Laurent
core  

Interrelations between BID and cyclophilins in the mitochondrial apoptotic pathway. [PDF]

, 2006
The BH3-only BCL-2 protein BID is thought, in some cases, to be responsible for the initiation of cytochrome c release from mitochondria during apoptosis.
Gillick, K.
core  

IgE to cyclophilins in pollen allergic children: epidemiological, clinical and diagnostic relevance of a neglected panallergen

Background: - Cyclophilins are ubiquitous panallergens whose epidemiological, diagnostic, and clinical relevance is largely unknown and whose sensitization is rarely examined in routine allergy practice.
Ricci, Giampaolo, Bernardini, Roberto, Bianchi, Annamaria, Macrì, Francesco, Giannetti, Arianna, Moschese, Viviana, Calvani, Mauro, Matricardi, Paolo Maria, Panetta, Valentina, Dello Iacono, Iride, Caffarelli, Carlo, Di Rienzo Businco, Andrea, Paravati, Francesco, Potapova, Ekaterina, Varin, Elena, Pingitore, Giuseppe, Pelosi, Umberto, Tripodi, Salvatore, Miraglia del, Michele Miraglia, Gallucci, Marcella, Tosca, Mariangela, Maiello, Nunzia, Cervone, Rosa, Asero, Riccardo, Peroni, Diego, Casani, Antonella, Lidholm, Jonas, Miraglia Del Giudice, Michele, Frediani, Tullio, Scala, Enrico, Comberiati, Pasquale, Zicari, Anna Maria, Chini, Loredana, Mattsson, Lars, De Castro, Giovanna   +34 more
core   +2 more sources

Enzyme activity and structural features of three single-domain phloem cyclophilins from Brassica napus

, 2019
Cyclophilins (CYPs) are a group of ubiquitous prolyl cis/trans isomerases (PPIases). It was shown that plants possess the most diverse CYP families and that these are abundant in the phloem long-distance translocation stream.
Betzel, Christian, Kehr, Julia, Falke, Sven, Thieß, Melanie, Rose, Victoria, Garbe, Marcel, Hanhart, Patrizia   +6 more
core   +1 more source