Results 191 to 200 of about 3,458 (212)
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Redox regulation of cyclophilin A by glutathionylation
PROTEOMICS, 2006AbstractUsing redox proteomics techniques to characterize the thiol status of proteins in human T lymphocytes, we identified cyclophilin A (CypA) as a specifically oxidized protein early after mitogen activation. CypA is an abundantly expressed cytosolic protein, target of the immunosuppressive drug cyclosporin A (CsA), for which a variety of functions
Ghezzi, Pietro +14 more
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Role of cyclophilin a during oncogenesis
Archives of Pharmacal Research, 2010Cyclophilins (Cyps) are ubiquitously expressed proteins that are evolutionarily conserved. CypA is the most abundant among the Cyps and is expressed in the cytosol. With its chaperone and PPIase activities, CypA contributes to the maintenance of correct conformation of nascent or denatured proteins and also provides protection against environmental ...
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Cyclophilin A as a Target of Cisplatin Chemosensitizers
Current Cancer Drug Targets, 2014Platinum-based chemotherapeutics are the mainstay of treatment of a range of tumors achieving high response rates but limited in the course of disease by appearance of drug resistance. Tumor cells respond with reduced uptake and increased intracellular inactivation of the drugs, as well as increased DNA repair and general resistance to ...
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Crosstalk between cyclophilins and T lymphocytes in coronary artery disease
Experimental Cell Research, 2021Sandra Gegunde +2 more
exaly
The role of cyclophilins in viral infection and the immune response
Journal of Infection, 2022Yaru Wu, Zhenling Ma, Wei Liu
exaly
Cyclophilins and their possible role in the stress response
International Journal of Experimental Pathology, 2001Richard J Heads
exaly

