Results 191 to 200 of about 3,458 (212)
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Redox regulation of cyclophilin A by glutathionylation

PROTEOMICS, 2006
AbstractUsing redox proteomics techniques to characterize the thiol status of proteins in human T lymphocytes, we identified cyclophilin A (CypA) as a specifically oxidized protein early after mitogen activation. CypA is an abundantly expressed cytosolic protein, target of the immunosuppressive drug cyclosporin A (CsA), for which a variety of functions
Ghezzi, Pietro   +14 more
openaire   +2 more sources

Role of cyclophilin a during oncogenesis

Archives of Pharmacal Research, 2010
Cyclophilins (Cyps) are ubiquitously expressed proteins that are evolutionarily conserved. CypA is the most abundant among the Cyps and is expressed in the cytosol. With its chaperone and PPIase activities, CypA contributes to the maintenance of correct conformation of nascent or denatured proteins and also provides protection against environmental ...
openaire   +2 more sources

Cyclophilin A as a Target of Cisplatin Chemosensitizers

Current Cancer Drug Targets, 2014
Platinum-based chemotherapeutics are the mainstay of treatment of a range of tumors achieving high response rates but limited in the course of disease by appearance of drug resistance. Tumor cells respond with reduced uptake and increased intracellular inactivation of the drugs, as well as increased DNA repair and general resistance to ...
openaire   +2 more sources

Crosstalk between cyclophilins and T lymphocytes in coronary artery disease

Experimental Cell Research, 2021
Sandra Gegunde   +2 more
exaly  

The role of cyclophilins in viral infection and the immune response

Journal of Infection, 2022
Yaru Wu, Zhenling Ma, Wei Liu
exaly  

Cyclophilin Inhibitors

Current Hepatitis Reports, 2012
Robert Flisiak, Anna Parfieniuk-Kowerda
openaire   +1 more source

Cyclophilin

Science-Business eXchange, 2014
openaire   +1 more source

Cyclophilins and their possible role in the stress response

International Journal of Experimental Pathology, 2001
Richard J Heads
exaly  

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