Results 161 to 170 of about 257,826 (338)

Implications of Notch Signaling in Taste Cell Replacement [PDF]

open access: yes, 2017
Cyclophosphamide (CYP) was one of the first chemotherapy drugs developed and used to treat several types of cancer, by disrupting proliferative cells. Unfortunately, CYP is unable to differentiate between cancerous cells and healthy cells turning over ...
D\u27Alessandro, Nicholas B
core   +1 more source

Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz   +12 more
wiley   +1 more source

Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps   +8 more
wiley   +1 more source

Pharmacokinetics of cyclophosphamide in man [PDF]

open access: green, 1971
Joseph L. Cohen   +2 more
openalex   +1 more source

Do Gadolinium‐Based Contrasts Represent a High Risk for Genotoxicity in Mammalian Cells? A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The scientific rationale for this review stems from the increasing global use of gadolinium‐based contrast agents in medical imaging and the concerns over the long‐term environmental accumulation of gadolinium waste, which may pose biological risks.
Thiago Guedes Pinto   +2 more
wiley   +1 more source

From waste to reuse: Fenton degradation of anticancer drugs in hospital wastewater using iron mining residue

open access: yesJournal of Chemical Technology &Biotechnology, Volume 100, Issue 7, Page 1472-1481, July 2025.
Abstract BACKGROUND The heterogeneous photo‐Fenton process demands stable and efficient materials as catalysts to decompose hydrogen peroxide and generate reactive oxygen species to promote the degradation of organic contaminants in wastewater. In this study, the catalytic activity of an iron mining residue (IMR) was investigated for the heterogeneous ...
Nayara de M Costa‐Serge   +4 more
wiley   +1 more source

Risk adapted therapy for newly diagnosed multiple myeloma delivered through local cytogenetic laboratories in a National Clinical Trial: UKMRA RADAR study

open access: yeseJHaem, EarlyView.
Abstract The UKMRA RADAR study is a phase II/III clinical trial for newly diagnosed multiple myeloma patients eligible for autologous stem cell transplant. It offers a risk‐adapted approach with the addition of isatuximab for genetically high‐risk patients, evaluated using local cytogenetics laboratories rather than centralised testing.
Dipal Mehta   +12 more
wiley   +1 more source

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