Results 161 to 170 of about 154,825 (291)

Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii

Journal of Applied Toxicology, EarlyView.
ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz, Shira Paz, Rotem Saban, Inbar Zuker, Hagay Shmuely, Katy Gorshkov, Jwar Meetro, Shahrzad Tafazoli, Trung Vo, Gabriela Amiram, Carmit Shani Levi, Uri Lesmes, Ilan Samish   +12 more
wiley   +1 more source

Anti‐MDA5 and anti‐SSA/Ro52 antibodies double‐positive dermatomyositis overlapping with rheumatoid arthritis‐associated interstitial lung disease: A case report

International Journal of Rheumatic Diseases, Volume 25, Issue 12, Page 1437-1440, December 2022., 2022
Abstract Dermatomyositis (DM) is a poorly prognostic autoimmune disease the pathogenesis of which is multifactorial and not clearly defined. DM may be influenced by genes, environment, and immunity. The typical manifestations of DM are Gottron rash, heliotrope rash, rash on the shoulders and buttocks, erythema around fingernails, excessive keratosis of
Hong Xiong, QianRen Tan, Feng Luo, XueMei Yuan, Wukai Ma, XueMing Yao   +5 more
wiley   +1 more source

Transcriptome analysis to decipher the molecular underpinnings of response to treatment in systemic lupus erythematosus. [PDF]

RMD Open
Garantziotis P, Moysidou GS, Kapsala N, Flouda S, Nikolopoulos D, Chavatza K, Sentis G, Filia A, Malissovas N, Pieta A, Banos A, Katechis S, Fanouriakis A, Bertsias G, Boumpas DT.   +14 more
europepmc   +1 more source

Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor

Thoracic Cancer, Volume 13, Issue 23, Page 3420-3430, December 2022., 2022
Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor. Abstract Immune checkpoint inhibitors (ICIs) have successfully treated a number of different types of cancer, which is of great significance for cancer treatment.
Wenxian Wang, Qian Wang, Chunwei Xu, Ziming Li, Zhengbo Song, Yongchang Zhang, Xiuyu Cai, Shirong Zhang, Bin Lian, Wen Li, Anwen Liu, Ping Zhan, Hongbing Liu, Tangfeng Lv, Liyun Miao, Lingfeng Min, Yu Chen, Jingping Yuan, Feng Wang, Zhansheng Jiang, Gen Lin, Xingxiang Pu, Chuangzhou Rao, Dongqing Lv, Zongyang Yu, Xiaoyan Li, Chuanhao Tang, Chengzhi Zhou, Congying Xie, Junping Zhang, Hui Guo, Qian Chu, Rui Meng, Jingxun Wu, Rui Zhang, Liping Wang, Youcai Zhu, Xiao Hu, Yanru Xie, Xinqing Lin, Jing Cai, Fen Lan, Huijing Feng, Lin Wang, Wang Yao, Xuefei Shi, Jianhui Huang, Huafei Chen, Yinbin Zhang, Pingli Sun, Bing Wan, Fei Pang, Zanmei Xu, Kai Wang, Yuanli Xia, Mingxiang Ye, Dong Wang, Qing Wei, Shuitu Feng, Jianya Zhou, Jiexia Zhang, Donglai Lv, Wenbin Gao, Jing Kang, Genhua Yu, Xianbin Liang, Chengtao Yu, Lin Shi, Nong Yang, Lin Wu, Zhuan Hong, Wei Hong, Meiyu Fang, Yiping Zhang, Yuanzhi Lu, Guansong Wang, Shenglin Ma, Lu Si, Wenfeng Fang, Yong Song   +79 more
wiley   +1 more source

Molecular insight into the role of benzotriazole nanocapsule to deliver anticancer drug in smart drug delivery system. [PDF]

Sci Rep
Sajjad A, Sarfaraz S, Abdul Hamid MHS, Keasberry NA, Lakhani A, Sheikh NS, Ayub K.   +6 more
europepmc   +1 more source

Lenvatinib rechallenge in a patient with advanced thymic carcinoma: A case report

Thoracic Cancer, Volume 13, Issue 23, Page 3408-3411, December 2022., 2022
We present a case treated with “lenvatinib rechallenge” for advanced thymic carcinoma who was previously treated with lenvatinib followed by multiple cytotoxic agents. Shortly after lenvatinib rechallenge, rapid pleural and pericardial effusion reduction was observed. Our case might suggest lenvatinib rechallenge as a treatment option for patients with
Yuto Terashima, Taiki Hakozaki, Susumu Takeuchi, Yukio Hosomi   +3 more
wiley   +1 more source

Corrigendum to "Metronomic chemotherapy using capecitabine and cyclophosphamide in metastatic breast cancer - efficacy, tolerability and quality of life results from the phase II METRO trial" [The Breast 78 (2004) 103795]. [PDF]

Breast
Larsson F K, Adra J, Klint L, Linderholm B.   +3 more
europepmc   +1 more source

Stimulation of granulocytic colony formation in agar diffusion chambers implanted in cyclophosphamide pretreated mice [PDF]

, 1975
M. Y. Gordon, N. M. Blackett
openalex   +1 more source

Hormone Receptor Positive Breast Cancer in Young Women: A Review

Journal of Surgical Oncology, EarlyView.
ABSTRACT The global incidence of hormone‐positive breast cancer (HR+ BC) in young women is rising, though the underlying reasons remain unclear. HR+ disease in younger women appears to represent a distinct clinical entity compared to that in older women, exhibiting distinct clinicopathological characteristics, outcomes and responses to treatment ...
Nicola McShane, Alexandra Zaborowski, Mary O'Reilly, Damian McCartan, Ruth Prichard   +4 more
wiley   +1 more source

Distinct clinicopathological characteristics, genomic alteration and prognosis in breast cancer with concurrent TP53 mutation and MYC amplification

Thoracic Cancer, Volume 13, Issue 24, Page 3441-3450, December 2022., 2022
Breast cancer with concurrent TP53 mutation and MYC amplification demonstrated higher grade and stage, more positive HER2 status, higher Ki67 levels, and more mutations in genes involved in ERBB and TGF‐β signaling pathways, as well as exclusive FANCG/CDKN2B/QKI copy number amplifications.
Xiaoyi Lin, Xin Lin, Lijuan Guo, Yulei Wang, Guochun Zhang   +4 more
wiley   +1 more source