Results 171 to 180 of about 222,217 (297)

Functional Roles of Adenosine A2B and A3 Receptor Subtypes in the Bladder of Male Rats With A2B Receptor Deletion or Bladder Outlet Obstruction

Neurourology and Urodynamics, EarlyView.
ABSTRACT Purpose To investigate the adenosine receptor (AR) mechanism underlying bladder outlet obstruction (BOO)‐related bladder dysfunction, we examined the expression level of AR subtypes in bladder tissues, and the effects of AR subtypes A2B & A3 modulation on bladder activity using male BOO rats, and Dahl rats with A2B receptor deletion. Materials
Masahiro Kurobe, Ei‐ichiro Takaoka, Kanako Matsuoka, Shingo Kimura, Anne M. Robertson, Edwin K. Jackson, Lori A. Birder, Minoru Miyazato, Naoki Yoshimura   +8 more
wiley   +1 more source

Combination olaparib and cyclophosphamide cancer therapy exacerbates ovarian reserve depletion in mice with conditional loss of <i>Brca1</i> in oocytes. [PDF]

Front Endocrinol (Lausanne)
Cao Y, Jalil ZA, Mu X, Stringer JM, Zerafa N, Winship AL, Hutt KJ.   +6 more
europepmc   +1 more source

Chronic High‐Dose Ketamine Fails to Induce a Cystitis‐Like Phenotype in Mice Despite High Urinary Metabolite Levels

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Ketamine‑induced cystitis (KIC) is a severe complication of chronic ketamine misuse, yet the underlying mechanisms remain poorly understood. Established rodent models have demonstrated variable changes in voiding behavior and bladder histology, without exploring the sensory mechanisms underlying altered voiding and pain at all. This study
Jill Dewez, Ashlee Caldwell, Laura Schillebeeckx, Margot De Vis, Sylvia João Poseiro Coutinho Pinto, Evy Van Den Broek, Véronique Hendrickx, Katrien Luyten, Marcella Baldewijns, Jan Tytgat, Thomas Voets, Wouter Everaerts   +11 more
wiley   +1 more source

Modified Newcastle Regimen Improves Survival Despite Central Nervous System Relapse in Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma. [PDF]

EJHaem
Suh M, Cho H, Go H, Ryu JS, Kim S, Lee K, Chae EJ, Park CS, Song IH, Kim KW, Lim SB, Park IJ, Kim CW, Yoon YS, Hyung J, Yoon DH.   +15 more
europepmc   +1 more source

Early Remission of Cerebrospinal Fluid Interleukin‐6 After Initial Immunotherapy Predicts a Good Prognosis in Autoimmune Encephalitis

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Autoimmune encephalitis therapy requires adjusting the regimen based on therapeutic response; however, clinical indicators of this response remain unknown. Aim To determine the predictive capability of cerebrospinal fluid (CSF), electroencephalography (EEG), and brain magnetic resonance imaging (MRI) in identifying responders to ...
Yuta Madokoro, Yuto Uchida, Hiroyasu Inoue, Toyohiro Sato, Teppei Fujioka, Masayuki Mizuno, Shoji Kawashima, Masahiro Oomura, Noriyuki Matsukawa   +8 more
wiley   +1 more source

Prospective management of biopsy-proven ocular mucous membrane pemphigoid using an inflammation-oriented stepladder treatment strategy. [PDF]

AJO Int
Bachtalia K, Athanasiou V, Athanasiadou A, Mavrommati M, Palioura S.   +4 more
europepmc   +1 more source

Effectiveness and safety of efgartigimod in patients with anti‐NMDAR or anti‐LGI1 encephalitis and its 18F‐DPA714 PET imaging evaluation: A multicenter, single‐arm, prospective, observational real‐world study

Neuroprotection, EarlyView.
Abstract Background Efgartigimod disrupts the recycling of pathogenic IgG autoantibodies and may represent a candidate therapy for autoimmune encephalitis. This real‐world study evaluated the clinical efficacy, safety, and impact of efgartigimod on brain inflammation.
Huanyu Meng, Siqi Tu, Yifan Zhou, Ruinan Shen, Xiaoyu Chen, Zhaozhao Cheng, Limei Wang, Yan Wu, Jie Lu, Shengjun Wang, Yan Xu, Wanhui Lin, Sheng Chen   +12 more
wiley   +1 more source

Combination Induction Immunosuppression With Rituximab, Cyclophosphamide, and Prednisone for Fibrillary Glomerulonephritis

Kidney International Reports
Gabriel Sauvage, Reza Zonozi, Harish Seethapathy, Orhan Efe, Anushya Jeyabalan, Karen Laliberte, John L. Niles, Ayman Al Jurdi   +7 more
doaj   +1 more source

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran, Zaharadeen Jimoh, Tariq Issa, Nahla A. Gomaa   +3 more
wiley   +1 more source

Corrigendum to "Protective effects and metabolomics analysis of dihydromyricetin on cyclophosphamide-induced hepatotoxicity in mice" [Pharm. Sci. Adv. 3 (2025) 100063]. [PDF]

Pharm Sci Adv
Teng F, Wang H.
europepmc   +1 more source