Results 31 to 40 of about 257,826 (338)

Cyclophosphamide-Induced Severe Acute Hyponatremic Encephalopathy in Patients with Breast Cancer: Report of Two Cases

Case Reports in Oncology, 2014
Background: Cyclophosphamide is an alkylating agent widely used in antineoplastic and immunosuppressive therapies. Symptomatic hyponatremia can be a rare but life-threatening complication in patients treated with cyclophosphamide.
Michelle Baker, Maurie Markman, Jiaxin Niu   +2 more
doaj   +1 more source

Ameliorative action of farnesol on cyclophosphamide induced toxicity in mice [PDF]

Journal of HerbMed Pharmacology, 2018
Introduction: Cyclophosphamide is an alkylating agent with antineoplastic and immunosuppressive effects. Acrolein, one of its metabolites, is responsible for different toxic side effects such as oxidative stress, and cell death.
Atefeh Araghi, Hannaneh Golshahi, Farshad Baghban, Mohaddeseh Abouhosseini Tabari   +3 more
doaj   +1 more source

Toxicity Analysis in the ADEBAR Trial: Sequential Anthracycline-Taxane Therapy Compared with FEC120 for the Adjuvant Treatment of High-Risk Breast Cancer [PDF]

, 2012
Background: Data from meta-analyses have shown taxane-containing therapies to be superior to anthracycline-based treatments for high-risk breast cancer. Patients and Methods: The ADEBAR trial was a multicenter phase Ill trial in which patients with lymph
Aivazova-Fuchs, Viktoria, Andergassen, Ulrich, Annecke, Katja, Augustin, Doris, Friese, Klaus, Harbeck, Nadia, Hepp, Philip, Janni, Wolfgang, Jückstock, Julia K., Kiechle, Marion, Mohrmann, Svjetlana, Rack, Brigitte, Salmen, Jessica, Schönherr, Alexandra, Simon, Wolfgang, Wischnik, Arthur, Zwingers, Thomas   +16 more
core   +1 more source

A Personalized Rituximab Retreatment Approach Based on Clinical and B-Cell Biomarkers in ANCA-Associated Vasculitis

Frontiers in Immunology, 2022
BackgroundTime to relapse after rituximab for the treatment of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is variable, and optimal retreatment strategy has remained unclear.
Jack Arnold, Edward M. Vital, Edward M. Vital, Shouvik Dass, Shouvik Dass, Aamir Aslam, Aamir Aslam, Andy C. Rawstron, Sinisa Savic, Sinisa Savic, Paul Emery, Paul Emery, Md Yuzaiful Md Yusof, Md Yuzaiful Md Yusof   +13 more
doaj   +1 more source

Phase 1 study of sirolimus in combination with oral cyclophosphamide and topotecan in children and young adults with relapsed and refractory solid tumors. [PDF]

, 2016
PurposeTo determine the maximum tolerated dose (MTD), toxicities, and pharmacodynamics effects of sirolimus combined with oral metronomic topotecan and cyclophosphamide in a pediatric population.Materials and methodsPatients who were 1 to 30 years of age
Allen, Shelly, DuBois, Steven G, Gustafson, W Clay, Hollinger, Fabienne, Karski, Erin E, Long-Boyle, Janel R, Matthay, Katherine K, Nasholm, Nicole M, Shiboski, Stephen, Vo, Kieuhoa T   +9 more
core   +1 more source

Investigation of curcumin effects on liver tissue in adult male rats treated with cyclophosphamide [PDF]

Journal of Advanced Biomedical Sciences, 2014
Background ; Objective: Cyclophosphamide is an antineoplastic drug that has many clinical uses in cancer treatment, but it has toxic effects due to creation of free radicals. In this study, the effects of curcumin" as an antioxidant drug” on liver tissue
Zahra khodaparast, ali reza yousofi, ameneh khoshvagti   +2 more
doaj   +2 more sources

Use of in vitro human keratinocyte models to study the effect of cooling on chemotherapy drug-induced cytotoxicity [PDF]

, 2014
A highly distressing side-effect of cancer chemotherapy is chemotherapy-induced alopecia (CIA). Scalp cooling remains the only treatment for CIA, yet there is no experimental evidence to support the cytoprotective capacity of cooling. We have established
Andrew Collett, Bodo, Boelsma, Boukamp, Breed, Brunsvig, Bulow, Christopher Dunnill, Corina J. van den Hurk, Dean, Deyrieux, Georgopoulos, Gregory, Grevelman, Inui, Itami, Itoh, Janssen, Janssen, Kayamba, Komen, Lane, Liu, Luanpitpong, Manon M. Komen, Margulis, Munstedt, Nabholtz, Nikolaos T. Georgopoulos, Omar Hussain, Paus, Protiere, Roh, van den Hurk, Wafaa Al-Tameemi, Wang, Watanabe   +36 more
core   +1 more source

Case Report: Haploidentical Bone Marrow Transplantation in Two Brothers With Wiskott–Aldrich Syndrome Using Their Father as the Donor

Frontiers in Pediatrics, 2021
Wiskott–Aldrich syndrome (WAS) is an X-linked genetic disorder with a variable phenotypic expression that includes thrombocytopenia, eczema, and immunodeficiency. Some patients may also exhibit autoimmune manifestations.
Jasmine Smith, Jasmine Smith, Jessica Hass Alfonso, Jessica Hass Alfonso, Naresh Reddivalla, Naresh Reddivalla, Pablo Angulo, Pablo Angulo, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis   +13 more
doaj   +1 more source

Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As a Graft Source for T-Cell-Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide. [PDF]

, 2017
Purpose T-cell-replete HLA-haploidentical donor hematopoietic transplantation using post-transplant cyclophosphamide was originally described using bone marrow (BM).
Al Malki, Monzr M, Anasetti, Claudio, Argall, Trevor, Bashey, Asad, Ciurea, Stefan O, Eapen, Mary, Fasan, Omotayo, Fuchs, Ephraim Joseph, Gaballa, MD, Sameh, Hamadani, Mehdi, McCurdy, Shannon R, Munshi, Pashna, Nakamura, Ryotaro, O\u27Donnell, Paul V, Perales, Miguel-Angel, Raj, Kavita, Rocha, Vanderson, Romee, Rizwan, Rowley, Scott, Salit, Rachel B, Soiffer, Robert J, Solh, Melhem, St Martin, Andrew, Zhang, Mei-Jie   +23 more
core   +2 more sources

Long-Term Cyclophosphamide Treatment in a Case with Serpiginous Choroiditis

Case Reports in Ophthalmology, 2010
Purpose: To report the effect of long-term therapy with the alkylating agent cyclophosphamide in a case with serpiginous choroiditis and thus to contribute to the previously reported few cases showing the beneficial effect of long-term cyclophosphamide ...
Ozlem G. Sahin
doaj   +1 more source