Results 21 to 30 of about 203,753 (294)

A small dose of toxicology : role of mitochondrial dysfunction in hepatic and skeletal muscle toxicity [PDF]

, 2005
Research over the last decade has extended the prevailing view of mitochondrial function well beyond its critical bioenergetic role in supplying ATP.
Kaufmann, Priska M.
core   +1 more source

Effect of cytostatic drugs on microbial behaviour in membrane bioreactor system [PDF]

, 2010
The aim of this work is to evaluate the influence of cyclophosphamide and its principal metabolites (CPs) on microbial behaviour in a membrane bioreactor system. Two laboratory-scale membrane bioreactors (MBR) were run in parallel with a sludge retention
Delgado, Luis Fernando, Albasi, Claire, Gonzalez, Carlos, Schetrite, Sylvie   +3 more
core   +1 more source

Rapamycin Prevents cyclophosphamide-induced Over-activation of Primordial Follicle pool through PI3K/Akt/mTOR Signaling Pathway in vivo

Journal of Ovarian Research, 2017
Background Primordial follicular depletion has thought to be a common adverse effect of chemotherapy especially for female of reproductive age. The study aimed to evaluate the protective effect of rapamycin on the primordial follicles and its potential ...
Linyan Zhou, Yanqiu Xie, Song Li, Yihua Liang, Qi Qiu, Haiyan Lin, Qingxue Zhang   +6 more
doaj   +1 more source

Cognitive impairment and elevated peripheral cytokines in breast cancer patients receiving chemotherapy

Arquivos de Neuro-Psiquiatria, 2022
Background Anthracyclines-based regimen (5-fluorouracil, doxorubicin, and cyclophosphamide (FAC); cyclophosphamide, epirubicin, and 5-fluorouracil [CEF]) and non-anthracycline based regimens (cyclophosphamide, methotrexate, and 5-fluorouracil [
Mohd Ashif Khan, Dinesh Bhurani, Ubedul Hoda, Nouroz Sehar, Nidhi Agarwal   +4 more
doaj   +1 more source

Cyclophosphamide-Induced Severe Acute Hyponatremic Encephalopathy in Patients with Breast Cancer: Report of Two Cases

Case Reports in Oncology, 2014
Background: Cyclophosphamide is an alkylating agent widely used in antineoplastic and immunosuppressive therapies. Symptomatic hyponatremia can be a rare but life-threatening complication in patients treated with cyclophosphamide.
Michelle Baker, Maurie Markman, Jiaxin Niu   +2 more
doaj   +1 more source

N-acetylcysteine modulates cyclophosphamide-induced immunosuppression, liver injury, and oxidative stress in miniature pigs

Journal of Animal Science and Technology, 2020
Cyclophosphamide, a cytotoxic anticancer agent, induces immunosuppression and has several adverse effects. N-acetylcysteine alleviates oxidative stress, liver injury, and intestinal tissue damage. The present study
Kyung Soo Kang, Sangsu Shin, Sang In Lee
doaj   +1 more source

Effect of cytostatic drug presence on extracellular polymeric substances formation in municipal wastewater treated by membrane bioreactor [PDF]

, 2010
The effect of the cyclophosphamide and its mean metabolites on extracellular polymeric substances (EPS) formation was investigated. Two lab-scale membrane bioreactors were followed in parallel (one with the cytostatic drugs, the second without ...
Delgado, L.F., Avella, Catalina, Delgado, Luis Fernando, Avella, A.C., Görner, Tatiana, Albasi, Claire, de Donato, Ph., Galmiche, M., Görner, T., De Donato, Philippe   +9 more
core   +1 more source

The Effect of Cyclophosphamide Chemotherapy on Ovarian AntiMüllerian Hormone Levels in Breast Cancer Patients

Indonesian Journal of Obstetrics and Gynecology, 2018
Objective: To evaluate cyclophosphamide effects on Anti- Müllerian hormone (AMH) levels in breast cancer patients treated with cyclophosphamide chemotherapy. Methods: This cohort prospective study was conducted in Dr.
Elisabeth G.K. Liga, Nusratuddin Abdullah, Eddy Tiro, St. Maisuri T. Chalid   +3 more
doaj   +1 more source

Ameliorative action of farnesol on cyclophosphamide induced toxicity in mice [PDF]

Journal of HerbMed Pharmacology, 2018
Introduction: Cyclophosphamide is an alkylating agent with antineoplastic and immunosuppressive effects. Acrolein, one of its metabolites, is responsible for different toxic side effects such as oxidative stress, and cell death.
Atefeh Araghi, Hannaneh Golshahi, Farshad Baghban, Mohaddeseh Abouhosseini Tabari   +3 more
doaj   +1 more source

An Autopsy of Acute Adrenal Insufficiency Resulting from Infarction of Both Adrenal Glands, in a Pregnant Woman with Metastatic Carcinoma of the Breast [PDF]

Journal of Clinical and Diagnostic Research, 2021
Acute Adrenal Insufficiency (AAI) is a life-threatening medical emergency, associated with high mortality, and requires early diagnosis and prompt management.
Gwendolyn Fernandes, Sharada Datar
doaj   +1 more source