Results 21 to 30 of about 175,213 (250)

An Autopsy of Acute Adrenal Insufficiency Resulting from Infarction of Both Adrenal Glands, in a Pregnant Woman with Metastatic Carcinoma of the Breast [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Acute Adrenal Insufficiency (AAI) is a life-threatening medical emergency, associated with high mortality, and requires early diagnosis and prompt management.
Gwendolyn Fernandes, Sharada Datar
doaj   +1 more source

Metabolism of cyclophosphamide [PDF]

open access: yesCancer, 1967
The in vivo activation of cyclophosphamide (Endoxan) to cytostatic and alkylating metabolites has been studied. Endoxan is metabolized to the weak anion by microsomal dealkylation in the rat's liver; this product is the first alkylating metabolite.
N, Brock, H J, Hohorst
openaire   +2 more sources

Investigation of curcumin effects on liver tissue in adult male rats treated with cyclophosphamide [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2014
Background ; Objective: Cyclophosphamide is an antineoplastic drug that has many clinical uses in cancer treatment, but it has toxic effects due to creation of free radicals. In this study, the effects of curcumin" as an antioxidant drug” on liver tissue
Zahra khodaparast   +2 more
doaj   +2 more sources

Long-Term Cyclophosphamide Treatment in a Case with Serpiginous Choroiditis

open access: yesCase Reports in Ophthalmology, 2010
Purpose: To report the effect of long-term therapy with the alkylating agent cyclophosphamide in a case with serpiginous choroiditis and thus to contribute to the previously reported few cases showing the beneficial effect of long-term cyclophosphamide ...
Ozlem G. Sahin
doaj   +1 more source

Effect of velvet antler on the immune activity of cyclophosphamide-induced immunosuppressed mice

open access: yesFood and Agricultural Immunology, 2022
To study the antioxidant and immune protection activity of velvet antler (VA) in cyclophosphamide-induced immunocompromised mice, BALB/c mice were intragastrically administered 100, 300, or 500 mg/(kg·d) VA for 30 days, and were intraabdominally injected
Liu Song-xin   +6 more
doaj   +1 more source

Immunomodulatory effects of complex probiotics on the immuno-suppressed mice induced by cyclophosphamide

open access: yesFrontiers in Microbiology, 2023
IntroductionPrevious studies have reported the beneficial effects of Bifidobacterium animalis subsp. lactis XLTG11, Lacticaseibacillus casei Zhang, and Lactiplantibacillus plantarum P8, respectively.
Weiwei Ma   +8 more
doaj   +1 more source

Pulmonary manifestations of systemic sclerosis

open access: yesThe Journal of Association of Chest Physicians, 2022
Systemic sclerosis (SSc) is an autoimmune connective tissue disease that primarily involve skin. Pulmonary involvements are important as they influence the outcome of SSc.
Supriya Sarkar
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Extracorporeal shockwave against inflammation mediated by GPR120 receptor in cyclophosphamide-induced rat cystitis model

open access: yesMolecular Medicine, 2018
Background We tested the hypothesis that extracorporeal shockwave treatment (ESWT) can abolish inflammation and restore urothelial barrier integrity in acute interstitial cystitis by upregulating the fatty acid receptor GPR120.
Yi-Ling Chen   +5 more
doaj   +1 more source

Cyclophosphamide augments the efficacy of in situ vaccination in a mouse melanoma model

open access: yesFrontiers in Oncology, 2023
IntroductionWe have previously shown that an intratumoral (IT) injection of the hu14.18-IL2 immunocytokine (IC), an anti-GD2 antibody linked to interleukin 2, can serve as an in situ vaccine and synergize with local radiotherapy (RT) to induce T cell ...
Noah Tsarovsky   +15 more
doaj   +1 more source

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