Results 21 to 30 of about 217,133 (287)

Administration of cyclophosphamide to rats induces pica and potentiates 5-hydroxytryptamine synthesis in the intestine without causing severe intestinal injury

Journal of Pharmacological Sciences, 2021
The effects of cyclophosphamide on 5-hydroxytryptamine (5-HT) synthesis in the intestinal tissue of rats were investigated. Rats received 120 mg/kg cyclophosphamide intraperitoneally as a single administration, and kaolin and food intake was measured by ...
Akihisa Kamiya, Takuji Machida, Megumi Hirano, Maiko Machida, Saki Shiga, Naoya Hamaue, Masahiko Hirafuji, Kenji Iizuka   +7 more
doaj   +1 more source

A Case of a 40-year-old Female with Speech Disturbance. [PDF]

Ann Clin Transl Neurol
Annals of Clinical and Translational Neurology, EarlyView.
Lorah V, Robers MV.
europepmc   +2 more sources

A study of ovarian cancer patients treated with dose-intensive chemotherapy supported with peripheral blood progenitor cells mobilised by filgrastim and cyclophosphamide [PDF]

, 1996
Summary We have shown that large numbers of haemopoietic progenitor cells are mobilised into the blood after filgrastim [granulocyte colony-stimulating factor (G-CSF)] alone and filgrastim following cyclophosphamide chemotherapy in previously untreated
Dexter, TM, C Gill, D Crowther, Gill, C, NG Testa, Weaver, A, Testa, NG, A Weaver, B Jenkins, R Pettengell, Collins, CD, Crowther, D, A Watson, Pettengell, R, Wrigley, E, J Chang, TM Dexter, Watson, A, CD Collins, E Wrigley, Chang, J, Jenkins, B   +21 more
core   +1 more source

THE ANTITOXIC EFFECT OF THE ROSUVASTATIN IN THE CYCLOPHOSPHAMIDE-INDUCED LIVER TOXICITY IN MALE RATS [PDF]

Assiut Veterinary Medical Journal
The study aims to examine the protective effect of rosuvastatin on liver toxicity caused by cyclophosphamide, including tissue, inflammatory markers, and oxidative damage. Twenty-four rats were separated into three distinct groups.
RANA ATTARBASHEE
doaj   +1 more source

Long-Term Effects of Cyclophosphamide in Sustained Remission in Childhood Steroid-resistant Nephrotic Syndrome

Saudi Journal of Kidney Diseases and Transplantation, 2022
Nephrotic syndrome (NS) is a chronic renal disease that can progress into end-stage renal disease within 5 years if no remission occurs. Achieving optimal remission is important to obtain better outcomes of treating childhood steroid-resistant NS (SRNS).
Eka L Hidayati, Dimas D Saputro, Laksmi Bestari, Zakiudin Munasir, Achmad Rafli   +4 more
doaj   +1 more source

Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth [PDF]

, 2009
Background: Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to ...
Amy Prosser, Robinson, B.W.S., Currie, A.J., Scalzo, A.A., Joanne Salmons, Robbert G van der Most, Mark J Smyth, Bruce W S Robinson, Salmons, J., Lake, R.A., Smyth Mark J., Andrew J Currie, Amanda L Cleaver, Prosser, Amy, van der Most, R.G., Degli-Esposti, M.A., Salmons, Joanne, Lake, Richard A., Prosser, A., Prosser Amy, Nowak, A.K., Currie, Andrew J., van der Most Robbert G., Smyth, M.J., Robinson Bruce W. S., Lake Richard A., Degli-Esposti, Mariapia A., Scalzo Anthony A., Currie Andrew J., Nowak, Anna K., Sathish Mahendran, Cleaver, Amanda L., Richard A Lake, Nowak Anna K., van der Most, Robbert G., Larma, I., Mahendran, S., Anna K Nowak, Degli-Esposti Mariapia A., Anthony A Scalzo, Cleaver, A.L., Robinson, Bruce W.S., Larma, Irma, Irma Larma, Cleaver Amanda L., Smyth, Mark J., Larma Irma, Mehendran, Sathish, Scalzo, Anthony A., Salmons Joanne, Mahendran Sathish, Mariapia A Degli-Esposti   +51 more
core   +2 more sources

Metabolism of cyclophosphamide [PDF]

Cancer, 1967
The in vivo activation of cyclophosphamide (Endoxan) to cytostatic and alkylating metabolites has been studied. Endoxan is metabolized to the weak anion by microsomal dealkylation in the rat's liver; this product is the first alkylating metabolite.
N, Brock, H J, Hohorst
openaire   +2 more sources

Post-transplant cyclophosphamide-induced cardiotoxicity: A comprehensive review [PDF]

Journal of Cardiovascular and Thoracic Research
Cyclophosphamide-induced cardiotoxicity, associated with its toxic metabolite acrolein, is a significant concern and unresolved issue, especially when cyclophosphamide is administrated in high doses.
Azin Alizadehasl, Bita Shahrami, Reza Rahbarghazi, Azam Yalameh Aliabadi, Seyedeh Fatemeh Hosseini Jebelli, Yasamin Afsari Zonooz, Hoda Hakimian, Farzaneh Fathi, Sara Forati, Aysa Rezabakhsh   +9 more
doaj   +1 more source

An Autopsy of Acute Adrenal Insufficiency Resulting from Infarction of Both Adrenal Glands, in a Pregnant Woman with Metastatic Carcinoma of the Breast [PDF]

Journal of Clinical and Diagnostic Research, 2021
Acute Adrenal Insufficiency (AAI) is a life-threatening medical emergency, associated with high mortality, and requires early diagnosis and prompt management.
Gwendolyn Fernandes, Sharada Datar
doaj   +1 more source

Effect of cytostatic drugs on microbial behaviour in membrane bioreactor system [PDF]

, 2010
The aim of this work is to evaluate the influence of cyclophosphamide and its principal metabolites (CPs) on microbial behaviour in a membrane bioreactor system. Two laboratory-scale membrane bioreactors (MBR) were run in parallel with a sludge retention
Delgado, Luis Fernando, Albasi, Claire, Gonzalez, Carlos, Schetrite, Sylvie   +3 more
core   +1 more source