Nephrotoxicity Risk of Cyclophosphamide in Lupus Model [PDF]
Cyclophosphamide is one of the standard therapies for lupus, especially lupus nephritis based on its immunosuppressive effect. However, cyclophosphamide is also known as a nephrotoxic agent.
Niken Indriyanti
doaj +5 more sources
Long-Term Cyclophosphamide Treatment in a Case with Serpiginous Choroiditis [PDF]
Purpose: To report the effect of long-term therapy with the alkylating agent cyclophosphamide in a case with serpiginous choroiditis and thus to contribute to the previously reported few cases showing the beneficial effect of long-term cyclophosphamide ...
Ozlem G. Sahin
doaj +3 more sources
Bortezomib-cyclophosphamide-dexamethasone induction/consolidation and bortezomib maintenance for transplant-eligible newly diagnosed multiple myeloma: phase 2 multicenter trial [PDF]
We conducted a phase II trial to prospectively evaluate the efficacy and safety of bortezomib-cyclophosphamide-dexamethasone (VCD) induction, autologous stem cell transplantation (ASCT), VCD consolidation, and bortezomib maintenance in transplant ...
Takayuki Ishikawa (12081674) +29 more
core +1 more source
Hemorrhagic cystitis in children treated with alkylating agent cyclophosphamide: The experience of a medical center in Taiwan [PDF]
Background/Purpose: Hemorrhagic cystitis is a common complication with chemotherapeutic alkylating agents. We investigated the possible prognostic factors of cyclophosphamide-induced hemorrhagic cystitis in children. Methods: Medical records of children
Wang, Ching-Chia;Weng, Te-I;Lu, Meng-Yao;Yang, Rong-Sen;Lin, Kai-Hsin;Wu, Mei-Hwan;Liu, Shing-Hwa +1 more
core +1 more source
Comparison of Post-transplant Cyclophosphamide Containing Immunosuppressive Regimen with Standard Immunosuppressive Regimen in Allogeneic Stem Cell Transplantation from Matched Sibling Donor [PDF]
Aim:Allogeneic stem cell transplantation (ASCT) is the only treatment that can cure most of malignant hematological diseases with the risk of some serious complications such as graft-versus-host disease (GVHD).
Osman KARA +3 more
core +1 more source
Nephrotic syndrome (NS) is a chronic renal disease that can progress into end-stage renal disease within 5 years if no remission occurs. Achieving optimal remission is important to obtain better outcomes of treating childhood steroid-resistant NS (SRNS).
Eka L Hidayati +4 more
doaj +1 more source
A study of ovarian cancer patients treated with dose-intensive chemotherapy supported with peripheral blood progenitor cells mobilised by filgrastim and cyclophosphamide [PDF]
Summary We have shown that large numbers of haemopoietic progenitor cells are mobilised into the blood after filgrastim [granulocyte colony-stimulating factor (G-CSF)] alone and filgrastim following cyclophosphamide chemotherapy in previously untreated
Dexter, TM +21 more
core +1 more source
THE ANTITOXIC EFFECT OF THE ROSUVASTATIN IN THE CYCLOPHOSPHAMIDE-INDUCED LIVER TOXICITY IN MALE RATS [PDF]
The study aims to examine the protective effect of rosuvastatin on liver toxicity caused by cyclophosphamide, including tissue, inflammatory markers, and oxidative damage. Twenty-four rats were separated into three distinct groups.
RANA ATTARBASHEE
doaj +1 more source
Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth [PDF]
Background: Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to ...
Amy Prosser +51 more
core +2 more sources
Post-transplant cyclophosphamide-induced cardiotoxicity: A comprehensive review [PDF]
Cyclophosphamide-induced cardiotoxicity, associated with its toxic metabolite acrolein, is a significant concern and unresolved issue, especially when cyclophosphamide is administrated in high doses.
Azin Alizadehasl +9 more
doaj +1 more source

