Results 11 to 20 of about 175,213 (250)

Nephrotoxicity Risk of Cyclophosphamide in Lupus Model

Journal of Tropical Pharmacy and Chemistry, 2021
Cyclophosphamide is one of the standard therapies for lupus, especially lupus nephritis based on its immunosuppressive effect. However, cyclophosphamide is also known as a nephrotoxic agent.
Niken Indriyanti
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THE ANTITOXIC EFFECT OF THE ROSUVASTATIN IN THE CYCLOPHOSPHAMIDE-INDUCED LIVER TOXICITY IN MALE RATS [PDF]

Assiut Veterinary Medical Journal
The study aims to examine the protective effect of rosuvastatin on liver toxicity caused by cyclophosphamide, including tissue, inflammatory markers, and oxidative damage. Twenty-four rats were separated into three distinct groups.
RANA ATTARBASHEE
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Long-Term Effects of Cyclophosphamide in Sustained Remission in Childhood Steroid-resistant Nephrotic Syndrome

Saudi Journal of Kidney Diseases and Transplantation, 2022
Nephrotic syndrome (NS) is a chronic renal disease that can progress into end-stage renal disease within 5 years if no remission occurs. Achieving optimal remission is important to obtain better outcomes of treating childhood steroid-resistant NS (SRNS).
Eka L Hidayati, Dimas D Saputro, Laksmi Bestari, Zakiudin Munasir, Achmad Rafli   +4 more
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Post-transplant cyclophosphamide-induced cardiotoxicity: A comprehensive review [PDF]

Journal of Cardiovascular and Thoracic Research
Cyclophosphamide-induced cardiotoxicity, associated with its toxic metabolite acrolein, is a significant concern and unresolved issue, especially when cyclophosphamide is administrated in high doses.
Azin Alizadehasl, Bita Shahrami, Reza Rahbarghazi, Azam Yalameh Aliabadi, Seyedeh Fatemeh Hosseini Jebelli, Yasamin Afsari Zonooz, Hoda Hakimian, Farzaneh Fathi, Sara Forati, Aysa Rezabakhsh   +9 more
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N-acetylcysteine modulates cyclophosphamide-induced immunosuppression, liver injury, and oxidative stress in miniature pigs

Journal of Animal Science and Technology, 2020
Cyclophosphamide, a cytotoxic anticancer agent, induces immunosuppression and has several adverse effects. N-acetylcysteine alleviates oxidative stress, liver injury, and intestinal tissue damage. The present study
Kyung Soo Kang, Sangsu Shin, Sang In Lee
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Rapamycin Prevents cyclophosphamide-induced Over-activation of Primordial Follicle pool through PI3K/Akt/mTOR Signaling Pathway in vivo

Journal of Ovarian Research, 2017
Background Primordial follicular depletion has thought to be a common adverse effect of chemotherapy especially for female of reproductive age. The study aimed to evaluate the protective effect of rapamycin on the primordial follicles and its potential ...
Linyan Zhou, Yanqiu Xie, Song Li, Yihua Liang, Qi Qiu, Haiyan Lin, Qingxue Zhang   +6 more
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Cognitive impairment and elevated peripheral cytokines in breast cancer patients receiving chemotherapy

Arquivos de Neuro-Psiquiatria, 2022
Background Anthracyclines-based regimen (5-fluorouracil, doxorubicin, and cyclophosphamide (FAC); cyclophosphamide, epirubicin, and 5-fluorouracil [CEF]) and non-anthracycline based regimens (cyclophosphamide, methotrexate, and 5-fluorouracil [
Mohd Ashif Khan, Dinesh Bhurani, Ubedul Hoda, Nouroz Sehar, Nidhi Agarwal   +4 more
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The Effect of Cyclophosphamide Chemotherapy on Ovarian AntiMüllerian Hormone Levels in Breast Cancer Patients

Indonesian Journal of Obstetrics and Gynecology, 2018
Objective: To evaluate cyclophosphamide effects on Anti- Müllerian hormone (AMH) levels in breast cancer patients treated with cyclophosphamide chemotherapy. Methods: This cohort prospective study was conducted in Dr.
Elisabeth G.K. Liga, Nusratuddin Abdullah, Eddy Tiro, St. Maisuri T. Chalid   +3 more
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Cyclophosphamide-Induced Severe Acute Hyponatremic Encephalopathy in Patients with Breast Cancer: Report of Two Cases

Case Reports in Oncology, 2014
Background: Cyclophosphamide is an alkylating agent widely used in antineoplastic and immunosuppressive therapies. Symptomatic hyponatremia can be a rare but life-threatening complication in patients treated with cyclophosphamide.
Michelle Baker, Maurie Markman, Jiaxin Niu   +2 more
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Ameliorative action of farnesol on cyclophosphamide induced toxicity in mice [PDF]

Journal of HerbMed Pharmacology, 2018
Introduction: Cyclophosphamide is an alkylating agent with antineoplastic and immunosuppressive effects. Acrolein, one of its metabolites, is responsible for different toxic side effects such as oxidative stress, and cell death.
Atefeh Araghi, Hannaneh Golshahi, Farshad Baghban, Mohaddeseh Abouhosseini Tabari   +3 more
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