Cyclophosphamide, a cytotoxic anticancer agent, induces immunosuppression and has several adverse effects. N-acetylcysteine alleviates oxidative stress, liver injury, and intestinal tissue damage. The present study
Kyung Soo Kang, Sangsu Shin, Sang In Lee
doaj +1 more source
A small dose of toxicology : role of mitochondrial dysfunction in hepatic and skeletal muscle toxicity [PDF]
Research over the last decade has extended the prevailing view of mitochondrial function well beyond its critical bioenergetic role in supplying ATP.
Kaufmann, Priska M.
core +1 more source
Background Primordial follicular depletion has thought to be a common adverse effect of chemotherapy especially for female of reproductive age. The study aimed to evaluate the protective effect of rapamycin on the primordial follicles and its potential ...
Linyan Zhou +6 more
doaj +1 more source
Effect of cytostatic drugs on the sludge and on the mixed liquor characteristics of a cross-flow membrane bioreactor: Consequence on the process [PDF]
The influence of cyclophosphamide and its principal metabolites (CPs) on the physicochemical properties of the mixed liquor of a cross-flow membrane bioreactor and the consequences for membrane fouling were investigated.
Delgado, Luis Fernando +5 more
core +1 more source
Background: Cyclophosphamide is an alkylating agent widely used in antineoplastic and immunosuppressive therapies. Symptomatic hyponatremia can be a rare but life-threatening complication in patients treated with cyclophosphamide.
Michelle Baker +2 more
doaj +1 more source
Objective: To evaluate cyclophosphamide effects on Anti- Müllerian hormone (AMH) levels in breast cancer patients treated with cyclophosphamide chemotherapy. Methods: This cohort prospective study was conducted in Dr.
Elisabeth G.K. Liga +3 more
doaj +1 more source
What is new in the management of rapidly progressive glomerulonephritis? [PDF]
Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB +3 more
core +1 more source
Effect of cytostatic drug presence on extracellular polymeric substances formation in municipal wastewater treated by membrane bioreactor [PDF]
The effect of the cyclophosphamide and its mean metabolites on extracellular polymeric substances (EPS) formation was investigated. Two lab-scale membrane bioreactors were followed in parallel (one with the cytostatic drugs, the second without ...
Delgado, L.F. +9 more
core +1 more source
Comparison of Post-transplant Cyclophosphamide Containing Immunosuppressive Regimen with Standard Immunosuppressive Regimen in Allogeneic Stem Cell Transplantation from Matched Sibling Donor [PDF]
Aim:Allogeneic stem cell transplantation (ASCT) is the only treatment that can cure most of malignant hematological diseases with the risk of some serious complications such as graft-versus-host disease (GVHD).
Osman KARA +3 more
core +1 more source
Investigation of curcumin effects on liver tissue in adult male rats treated with cyclophosphamide [PDF]
Background ; Objective: Cyclophosphamide is an antineoplastic drug that has many clinical uses in cancer treatment, but it has toxic effects due to creation of free radicals. In this study, the effects of curcumin" as an antioxidant drug” on liver tissue
Zahra khodaparast +2 more
doaj +2 more sources

