Effect of cytostatic drugs on the sludge and on the mixed liquor characteristics of a cross-flow membrane bioreactor: Consequence on the process [PDF]
The influence of cyclophosphamide and its principal metabolites (CPs) on the physicochemical properties of the mixed liquor of a cross-flow membrane bioreactor and the consequences for membrane fouling were investigated.
Delgado, Luis Fernando +5 more
core +1 more source
Metabolism of cyclophosphamide [PDF]
The in vivo activation of cyclophosphamide (Endoxan) to cytostatic and alkylating metabolites has been studied. Endoxan is metabolized to the weak anion by microsomal dealkylation in the rat's liver; this product is the first alkylating metabolite.
N, Brock, H J, Hohorst
openaire +2 more sources
What is new in the management of rapidly progressive glomerulonephritis? [PDF]
Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB +3 more
core +1 more source
Investigation of curcumin effects on liver tissue in adult male rats treated with cyclophosphamide [PDF]
Background ; Objective: Cyclophosphamide is an antineoplastic drug that has many clinical uses in cancer treatment, but it has toxic effects due to creation of free radicals. In this study, the effects of curcumin" as an antioxidant drug” on liver tissue
Zahra khodaparast +2 more
doaj +2 more sources
Rheumatoid vasculitis of crural muscles confirmed by muscle biopsy in the absence of inflammatory myopathy: histologic and MRI study. [PDF]
A 60-year-old man who had been diagnosed as rheumatoid arthritis admitted to our hospital by dysesthesia on his legs with edema. Nerve conduction velocity test led to diagnosis of mononeuritis multiplex.
Eguchi, Katsumi +11 more
core +1 more source
Clinical pharmacokinetics of cyclophosphamide [PDF]
Cyclophosphamide is an extensively used anticancer and immunosuppressive agent. It is a prodrug undergoing a complicated process of metabolic activation and inactivation.
Sjoerd Rodenhuis +7 more
core +1 more source
Cyclophosphamide metabolic pathways. [PDF]
Cyclophosphamide (CY) is metabolized to 4-hydroxy-cyclophosphamide (HCY) in the hepatic cytochrome P-450 enzyme (CYP) system (CYP2B6 and/or CYP2C19). HCY enters cells as tautomer aldocyclophosphamide (AldoCY).
Kousuke Asaba (761596) +8 more
core +1 more source
Effect of velvet antler on the immune activity of cyclophosphamide-induced immunosuppressed mice
To study the antioxidant and immune protection activity of velvet antler (VA) in cyclophosphamide-induced immunocompromised mice, BALB/c mice were intragastrically administered 100, 300, or 500 mg/(kg·d) VA for 30 days, and were intraabdominally injected
Liu Song-xin +6 more
doaj +1 more source
IntroductionPrevious studies have reported the beneficial effects of Bifidobacterium animalis subsp. lactis XLTG11, Lacticaseibacillus casei Zhang, and Lactiplantibacillus plantarum P8, respectively.
Weiwei Ma +8 more
doaj +1 more source
Pulmonary manifestations of systemic sclerosis
Systemic sclerosis (SSc) is an autoimmune connective tissue disease that primarily involve skin. Pulmonary involvements are important as they influence the outcome of SSc.
Supriya Sarkar
doaj +1 more source

