Results 31 to 40 of about 222,217 (297)

Cyclophosphamide augments the efficacy of in situ vaccination in a mouse melanoma model

Frontiers in Oncology, 2023
IntroductionWe have previously shown that an intratumoral (IT) injection of the hu14.18-IL2 immunocytokine (IC), an anti-GD2 antibody linked to interleukin 2, can serve as an in situ vaccine and synergize with local radiotherapy (RT) to induce T cell ...
Noah Tsarovsky, Mildred Felder, Mackenzie Heck, Jacob Slowinski, Kayla Rasmussen, Sabrina VandenHeuvel, Jen Zaborek, Zachary S. Morris, Zachary S. Morris, Amy K. Erbe, Amy K. Erbe, Paul M. Sondel, Paul M. Sondel, Paul M. Sondel, Alexander L. Rakhmilevich, Alexander L. Rakhmilevich   +15 more
doaj   +1 more source

Hemorrhagic cystitis in children treated with alkylating agent cyclophosphamide: The experience of a medical center in Taiwan

, 2017
Background/Purpose: Hemorrhagic cystitis is a common complication with chemotherapeutic alkylating agents. We investigated the possible prognostic factors of cyclophosphamide-induced hemorrhagic cystitis in children. Methods: Medical records of children
Wang, Ching-Chia;Weng, Te-I;Lu, Meng-Yao;Yang, Rong-Sen;Lin, Kai-Hsin;Wu, Mei-Hwan;Liu, Shing-Hwa, 劉興華;吳美環;盧孟佑;楊榮森;翁德怡;林凱信;王景甲   +1 more
core   +1 more source

SBT (Composed of Panax ginseng and Aconitum carmichaeli) and Stigmasterol Enhances Nitric Oxide Production and Exerts Curative Properties as a Potential Anti-Oxidant and Immunity-Enhancing Agent

Antioxidants, 2022
Immune dysregulation is a risk factor for several diseases, including infectious diseases. Immunostimulatory agents have been used for the treatment of immune dysregulation, but deleterious adverse effects have been reported.
Na-Ra Han, Kyeoung-Cheol Kim, Ju-Sung Kim, Hi-Joon Park, Seong-Gyu Ko, Phil-Dong Moon   +5 more
doaj   +1 more source

Cyclophosphamide metabolic pathways.

, 2015
Cyclophosphamide (CY) is metabolized to 4-hydroxy-cyclophosphamide (HCY) in the hepatic cytochrome P-450 enzyme (CYP) system (CYP2B6 and/or CYP2C19). HCY enters cells as tautomer aldocyclophosphamide (AldoCY).
Kousuke Asaba (761596), Takuro Nishikawa (761591), Koichiro Kurauchi (761593), Yoshifumi Kawano (63865), Kazuro Ikawa (761595), Erika Watanabe (761594), Yasuhiro Okamoto (761598), Emiko Miyahara (761592), Takayuki Tanabe (761597)   +8 more
core   +1 more source

Extracorporeal shockwave against inflammation mediated by GPR120 receptor in cyclophosphamide-induced rat cystitis model

Molecular Medicine, 2018
Background We tested the hypothesis that extracorporeal shockwave treatment (ESWT) can abolish inflammation and restore urothelial barrier integrity in acute interstitial cystitis by upregulating the fatty acid receptor GPR120.
Yi-Ling Chen, Yuan-Ping Lin, Cheuk-Kwan Sun, Tien-Hung Huang, Hon-Kan Yip, Yen-Ta Chen   +5 more
doaj   +1 more source

Pneumonia and Lupus Nephritis With Posaconazole-Cyclophosphamide Co-administration Without Drug Interaction–Induced Toxicity [PDF]

, 2023
Paecilomyces variotii is an opportunistic mold that causes pulmonary infections in immunosuppressed humans that are often treated with triazole therapy.
Schmitt, Monica M, Ferré, Elise M N, Herrera, Alejandro, Webb, Taura, Michail S Lionakis, Hasni, Sarfaraz, Lewis, Russell E, Andes, David, Suraj Rajasimhan, Kobrin, Dale, David Andes, Ben Colton, Dale Kobrin, Joseph Pechacek, DiMaggio, Thomas, Elise M N Ferré, Taura Webb, Hammoud, Dima, Jonathan Bolaños, Afzali, Behdad, Behdad Afzali, Rajasimhan, Suraj, Lionakis, Michail S, Alejandro Herrera, Seyedmousavi, Seyedmojtaba, Seyedmojtaba Seyedmousavi, Pechacek, Joseph, Monica M Schmitt, Dima Hammoud, Thomas DiMaggio, Colton, Ben, Sarfaraz Hasni, Bolaños, Jonathan, Russell E Lewis   +33 more
core   +1 more source

the Investigating the Potential Hepatoprotective Effect of Quercetin in Male Rats ‎Following Acute Exposure to Cyclophosphamide

The Iraqi Journal of Veterinary Medicine, 2023
            This study aimed to assess the hepatoprotective efficacy of quercetin against ‎hepatotoxicity ‎induced by cyclophosphamide in a rat model. A total of 28 male ‎Wister albino rats (Rattus ‎norvegicus), with body ‎weights ranging from 195.
Mustafa M. Khalaf, Rana A Salih
doaj   +1 more source

Cyclophosphamide-induced seizures in a patient with neuropsychiatric systemic lupus erythematosus (NPSLE): A case report [PDF]

, 2023
Seizures are life-threatening complications of neuropsychiatric systemic lupus erythematosus (NPSLE) and are often associated with poor outcomes. Cyclophosphamide immunotherapy is the mainstay of NPSLE treatment.
Jing Wu, Lingshu Zhang, Wei Jiang, Jingyao Zhang, Ying Shi, Wu, Jing, Jiang, Wei, Zhang, Lingshu, Zhang, Jingyao, Shi, Ying   +9 more
core   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Optimization of the Flavonoid Extraction Process from the Stem and Leaves of Epimedium Brevicornum and Its Effects on Cyclophosphamide-Induced Renal Injury

Molecules, 2023
Cyclophosphamide (CTX) is a broad-spectrum alkylated antitumor drug. It is clinically used in the treatment of a variety of cancers, and renal toxicity is one of the adverse reactions after long-term or repeated use, which not only limits the therapeutic
Meiling Shi, Hongyan Pei, Li Sun, Weijia Chen, Ying Zong, Yan Zhao, Rui Du, Zhongmei He   +7 more
doaj   +1 more source