Results 61 to 70 of about 11,151 (188)
ABSTRACT Endogenous H2O2 participated in the ethylene‐dependent ripening and senescence process of horticultural fruit as a secondary messenger; however, the molecular mechanism beneath such a phenomenon has not been fully clarified until recently. By a conjoint analysis of metabolite, enzyme activities, gene expression profiles in AsA‐GSH cycle of ...
Libin Wang +12 more
wiley +1 more source
The absence of the meso-hydrogen atoms in meso-octaalkylporphyrinogens enable the generation of novel forms of the oxidized porphyrinogen, 'artificial porphyrins'. A stepwise four-electron oxidation of meso-octaalkylporphyrinogen transitionmetal
Carlo Floriani
doaj +2 more sources
SYNTHESIS, LSD1 INHIBITORY ACTIVITY, AND LSD1 BINDING MODEL OF OPTICALLY PURE LYSINE-PCPA CONJUGATES
Compounds that inhibit the catalytic function of lysine-specific demethylase 1 (LSD1) are interesting as therapeutic agents. Recently, we identified three lysine-phenylcyclopropylamine conjugates, NCD18, NCD25, and NCD41, which are potent LSD1 ...
Yukihiro Itoh +4 more
doaj +1 more source
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
wiley +1 more source
[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methanol
The title compound, C19H16FNO, crystallizes with two independent molecules in the asymmetric unit. In the two molecules, the dihedral angles between the benzene and quinoline rings are 72.6 (5) and 76.2 (5)°, between the ...
Hongshun Sun, Hong Xu, Yu-Long Li
doaj +1 more source
Ein verbessertes Niedertemperatur Syntheseverfahren hat die erste umfassende strukturelle und spektroskopische Charakterisierung von neutralem Hexacyanotrimethylencyclopropan (CN6CP) ermöglicht. Kombinierte IR/Raman‐, UV/Vis und ssNMR‐Analysen liefern tiefere Einblicke in die oxidationszustandsabhängige Ladungsverteilung, die σ‐Aromatizität des ...
Jan P. Soyka +8 more
wiley +1 more source
An improved low‐temperature synthesis enables the first comprehensive structural and spectroscopic characterisation of neutral hexacyanotrimethylenecyclopropane (CN6CP). Combined IR/Raman, UV–Vis and ssNMR analyses reveal a deeper understanding of its oxidation‐state‐dependent charge redistribution, σ‐aromaticity of the cyclopropane core, and redox ...
Jan P. Soyka +8 more
wiley +1 more source
Background Cyclopropane fatty acids (CPA) have been found in certain gymnosperms, Malvales, Litchi and other Sapindales. The presence of their unique strained ring structures confers physical and chemical properties characteristic of unsaturated fatty ...
Rawat Richa, Yu Xiao-Hong, Shanklin John
doaj +1 more source
Synthetic Ligands of Myeloid C‐Type Lectin Receptors
Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
wiley +1 more source
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