Results 51 to 60 of about 17,328 (234)

Rational design of cyclopropane-based chiral PHOX ligands for intermolecular asymmetric Heck reaction

Beilstein Journal of Organic Chemistry, 2014
A novel class of chiral phosphanyl-oxazoline (PHOX) ligands with a conformationally rigid cyclopropyl backbone was synthesized and tested in the intermolecular asymmetric Heck reaction.
Marina Rubina, William M. Sherrill, Alexey Yu. Barkov, Michael Rubin   +3 more
doaj   +1 more source

Preface to “Aziridine Chemistry”

Molecules, 2021
Aziridine is a nitrogen-containing three-membered ring with similar ring strain energy as other three-membered ring compounds, including cyclopropane and oxirane [...]
Hyun-Joon Ha
doaj   +1 more source

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

Pseudo-conjunction in the cyclopropane ring

, 1966
A survey of the available data on the properties of cyclopropane systems shows that the common assumption that cyclopropane can conjugate with unsaturated systems is questionable.
Miller, Ian James
core   +1 more source

Enantioselective Gas Chromatographic Analysis of Cyclopropane Derivatives

, 2005
Chirasil-beta-Dex was used as chiral stationary phase for the enantioselective gas chromatographic analysis of several new chiral cyclopropane derivatives.
Grass, Stéphane, Aboul-Enein, Hassan Y., Jiang, Zhengjin, Ghanem Abdallah, Ashraf, Aboul-Enein, Hassan, Lacrampe, Fabienne, Jiang, Z., Ghanem, Ashraf; id_orcid, Grass, Stefan, Müller, Paul   +9 more
core   +2 more sources

Design, Synthesis, and Antimicrobial Activity of Amide Derivatives Containing Cyclopropane

Molecules
As an important small organic molecule, cyclopropane is widely used in drug design. In this paper, fifty-three amide derivatives containing cyclopropane were designed and synthesized by introducing amide groups and aryl groups into cyclopropane through ...
Dongdong Chen, Yu Cheng, Lele Shi, Xueting Gao, Yuhang Huang, Zhenting Du   +5 more
doaj   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Divergent Access to Histone Deacetylase Inhibitory Cyclopeptides via Late- Stage Cyclopropane Ring Cleavage Strategy. Short Synthesis of Chlamydocin

, 2019
We present a unified step-economical strategy to access histone deacetylase inhibitory peptides, based on late-stage installation of zinc-binding functionalities via the cleavage of the strained cyclopropane ring in the common pluripotent cyclopropanol ...
Dzmitry, Zubrytski, Nele, Konrad, Gabor Zoltan, Elek, Kaur, Koppel, Margus, Lopp, Dzmitry, Kananovich, Ivar, Järving   +6 more
core   +1 more source

Catalytic Generation of Cationic Gold Carbene Complexes From 7‐Alkynylnorbornadienes and Their Intermolecular Cyclopropanation With Alkenes

Chemistry – A European Journal, EarlyView.
Efficient cationic gold(I)‐catalyzed intermolecular cyclopropanation of 7‐alkynylnorbornadiene derivatives has been developed. This methodology offers the synthesis of a new class of norbornene derivatives in high yield with excellent diastereoselectivity.
Kento Ishida, Kenta Toei, Fumiaki Tomi, Norio Sakai   +3 more
wiley   +1 more source

Crystal structures of two bicyclo[5.1.0]octanes: potassium trans-bicyclo[5.1.0]octane-4-carboxylate monohydrate and cis-bicyclo[5.1.0]octan-4-yl 4-bromobenzenesulfonate

Acta Crystallographica Section E: Crystallographic Communications, 2017
The crystal structures of the trans-fused compound potassium trans-bicyclo[5.1.0]octane-4-carboxylate monohydrate, K+·C9H13O2−·H2O, (I), and of cis-bicyclo[5.1.0]octan-4-yl 4-bromobenzenesulfonate, C14H17BrO3S, (II), have been determined.
Peter W. R. Corfield, Richard A. Kershaw
doaj   +1 more source