Results 31 to 40 of about 1,056 (157)
Complex of Cyclosporins Produced by Tolypocladium inflatum Isolated from Soil Sample of Buryatiya
Антибиотики и Химиотерапия, 2020 A micromycete culture was isolated from a soil sample of Buryatiya and identified as Tolypocladium inflatum No. 2. The culture was shown to produce a complex of cyclosporins ofunusual component structure: the content of cyclosporin A (55—60%) was the ...
M. V. Bibikova +4 more
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Cyclosporin A Treatment in Psoriasis: Monitoring by Neopterin Concentrations In Serum and Urine
Pteridines, 1993 Psoriasis is a hyperproliferative skin disorder in which immune mechanisms are thought to play a role. Recently, cyclosporin A has been found effective to treat psoriasis. However, mechanisms of action of cyclosporin A in patients are not well understood.
Sepp N. +5 more
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Upregulation of lysyl oxidase expression in cyclosporin A-induced gingival overgrowth
Journal of Dental Sciences, 2009 Lysyl oxidase (LOX) is involved in the initial steps of converting soluble monomers of collagen and elastin into insoluble fibers in the extracellular matrix. LOX was found to be upregulated in some fibrotic diseases.
Chung-Hung Tsai +2 more
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British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson +8 more
wiley +1 more source
Optimization of cyclosporin A production by Beauveria nivea in continuous fed-batch fermentation [PDF]
Archives of Biological Sciences, 2011 To develop the effective control method for fed-batch culture of cyclosporin A production, we chose fructose, L-valine and (NH4)2HPO4 as feeding nutrients and compared their productivities in relation to different concentrations.
Dong Huijun +3 more
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Organ Medicine, EarlyView.Serum galactose‐deficient IgA1 levels at 3 and 6 months predicted recurrent IgA nephropathy after kidney transplantation. Recipients without recurrence showed a rapid decline in galactose‐deficient IgA1 after transplantation. Early identification of recurrence risk provided a potential window for targeted post‐transplant intervention.
Ronghai Deng +10 more
wiley +1 more source
Comparison of two commercial cyclosporin assays [PDF]
Journal of Medical Biochemistry, 2007 A new Dade Behring Cyclosporin A (CsA) assay has been made commercially accessible recently. The aim of this study was to examine the analytical performance of this assay and the correlation with the Abbott Diagnostics assay.
Vučeljić Marina +3 more
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Pediatric Investigation, EarlyView.This study elucidates the critical pathogenic mechanisms of pediatric Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis (EBV‐HLH), where EBV infection triggers a cytokine storm leading to immune cell hyperactivation and tissue damage. Dynamic plasma biomarkers (EBV‐DNA, ferritin, and interferon‐γ) effectively predict treatment response ...
Feifei Liu +9 more
wiley +1 more source
Turkish Journal of Nephrology, 2019 Immune system activation play an important role in the pathogenesis of primary glomerulonephritis. Although various immunsupressive agents have been used in the treatment of primary glomerulonephritis, still there is not an efficacious therapy model.
Mustafa GÜLLÜLÜ +8 more
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Dermatopathology, 2016 Many cutaneous complications have been described in patients treated with cyclosporin. Alterations of the pilosebaceous unit such as hypertrichosis are particularly frequent. However, the occurrence of sebaceous hyperplasia is exceptional.
Begonia Cortés, Gürkan Kaya
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