Results 31 to 40 of about 49,424 (197)
Cyclosporin A Treatment in Psoriasis: Monitoring by Neopterin Concentrations In Serum and Urine
Psoriasis is a hyperproliferative skin disorder in which immune mechanisms are thought to play a role. Recently, cyclosporin A has been found effective to treat psoriasis. However, mechanisms of action of cyclosporin A in patients are not well understood.
Sepp N. +5 more
doaj +1 more source
Complex of Cyclosporins Produced by Tolypocladium inflatum Isolated from Soil Sample of Buryatiya
A micromycete culture was isolated from a soil sample of Buryatiya and identified as Tolypocladium inflatum No. 2. The culture was shown to produce a complex of cyclosporins ofunusual component structure: the content of cyclosporin A (55—60%) was the ...
M. V. Bibikova +4 more
doaj
Upregulation of lysyl oxidase expression in cyclosporin A-induced gingival overgrowth
Lysyl oxidase (LOX) is involved in the initial steps of converting soluble monomers of collagen and elastin into insoluble fibers in the extracellular matrix. LOX was found to be upregulated in some fibrotic diseases.
Chung-Hung Tsai +2 more
doaj +1 more source
Next Generation Hosts for Protein Recognition, Assembly and More
The original design of synthetic receptors for proteins was based on macrocycles with a hydrophobic core and a polar/charged periphery. This design, geared towards protein recognition, facilitates receptor self‐assembly. Macrocycle oligomerization, in turn, contributes to protein assembly as evidenced in many cocrystal structures.
Peter B. Crowley
wiley +1 more source
Comparison of two commercial cyclosporin assays [PDF]
A new Dade Behring Cyclosporin A (CsA) assay has been made commercially accessible recently. The aim of this study was to examine the analytical performance of this assay and the correlation with the Abbott Diagnostics assay.
Vučeljić Marina +3 more
doaj
Optimization of cyclosporin A production by Beauveria nivea in continuous fed-batch fermentation [PDF]
To develop the effective control method for fed-batch culture of cyclosporin A production, we chose fructose, L-valine and (NH4)2HPO4 as feeding nutrients and compared their productivities in relation to different concentrations.
Dong Huijun +3 more
doaj +1 more source
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija +6 more
wiley +1 more source
Immune system activation play an important role in the pathogenesis of primary glomerulonephritis. Although various immunsupressive agents have been used in the treatment of primary glomerulonephritis, still there is not an efficacious therapy model.
Mustafa GÜLLÜLÜ +8 more
doaj
ABSTRACT Background/Objectives Dupilumab is an anti‐interleukin (IL)‐4 receptor (IL‐4Rα) monoclonal antibody used to manage atopic dermatitis (AD). There is a paucity of real‐world Australian data for dupilumab in paediatric AD, especially regarding differences in clinical profiles between age groups.
Paul Sun Woo Kim +7 more
wiley +1 more source

