Results 41 to 50 of about 1,056 (157)
Responsive Materials, EarlyView.Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source
Turkish Journal of Hematology, 2009 Hemophagocyticlymphohistiocytosis is a life-threatening condition of severe hyperinflammation that results from an uncontrolled proliferation of activated lymphocytes and histiocytes secreting high amounts of inflammatory cytokines.
Sinem Akgül +4 more
doaj
Systemic Treatment of Psoriasis: Current Evidence on Efficacy and Safety
The Journal of Dermatology, EarlyView.ABSTRACT Systemic treatments for moderate‐to‐severe plaque psoriasis have been advanced from broad immunosuppressants up to agents more selectively targeting cytokines, cytokine receptors, or intracellular signaling. The current systemic treatments mainly consist of conventional systemic agents, biologics targeting tumor necrosis factor (TNF)‐α ...
Teppei Hagino, Naoko Kanda
wiley +1 more source
Asia-Pacific Journal of Clinical Oncology, EarlyView.We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija +6 more
wiley +1 more source
International Journal of Nanomedicine, 2013 Ling Zhang,1,2,# Zhi-Liang Zhao,3,# Xiao-Hong Wei,1 Jin-Hua Liu21School of Medicine, 2College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, 3Tongde Hospital of Zhejiang Province, Hangzhou, People’s Republic of ...
Zhang L, Zhao Z-L, Wei X-H, Liu J-H
doaj
Insights into the Roles of Cyclophilin A During Influenza Virus Infection
Viruses, 2013 Cyclophilin A (CypA) is the main member of the immunophilin superfamily that has peptidyl-prolyl cis-trans isomerase activity. CypA participates in protein folding, cell signaling, inflammation and tumorigenesis. Further, CypA plays critical roles in the
Wenjun Liu, Zhendong Zhao, Xiaoling Liu
doaj +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.Immune effector cell‐mediated enterocolitis is an emerging complication of CAR‐T therapy. This review summarizes its epidemiology, pathophysiology, diagnosis, endoscopic and histopathologic features, and evidence‐based management, emphasizing early recognition, multidisciplinary intervention, and step‐up therapy.
John A. Damianos +4 more
wiley +1 more source
Bile acid synthesis in HepG2 cells: effect of cyclosporin
Journal of Lipid Research, 1994 The hypothesis that cyclosporin specifically affects the pathway of bile acid synthesis that begins with 27-hydroxylation of cholesterol was evaluated in HepG2 cells, which synthesize chenodeoxycholic acid and cholic acid from endogenous 7 alpha ...
J Levy, K Budai, N B Javitt
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Risk Factors and Management of Gingival Enlargement: A Systematic Review and Meta‐Analysis
Journal of Clinical Periodontology, EarlyView.ABSTRACT Objective To identify risk factors/indicators of gingival enlargement (GE) and to summarise evidence for its management. Methods A systematic review was undertaken following PRISMA guidelines and divided into PECOTS and PICOTS questions, related to risk factors/indicators and treatment studies, respectively.
Luigi Nibali +5 more
wiley +1 more source
Preferential Solvation of Cyclosporin in Aqueous Mixtures of Some Polymeric Cosolvents [PDF]
ImmunoAnalysisBackground: Cyclosporin is a cyclic peptide-drug used as immunosuppressant for the prophylaxisof transplant rejection whose physicochemical properties in mixed aqueous solvent systems isstill not well understood.
María Ángeles Peña +4 more
doaj +1 more source