Results 41 to 50 of about 117 (84)

Environmental Determinants of Dengue Fever: ‎A Re‐Emerging Threat in the Middle East

open access: yesHealth Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background Re‐emerging of dengue fever (DF), a neglected disease‎, is a potential threat in tropical and subtropical countries. The increasing reporting of ‎positive ‎cases of DF in Middle East and consequently in Iran is a major reason for ‎concern.
Farideh Bagherzadeh   +6 more
wiley   +1 more source

The Immunogenicity and Safety of CYD-Tetravalent Dengue Vaccine (CYD-TDV) in Children and Adolescents: A Systematic Review

open access: yesActa Medica Indonesiana, 2017
Aim: to assess the immunogenicity and safety of CYD-tetravalent dengue vaccine (CYD-TDV) in children. Methods: comprehensive literature searches were conducted on various databases.
Raksheeth Agarwal   +4 more
doaj   +2 more sources

Antiviral and Immunomodulatory Effects of Zafirlukast Against Flaviviruses via Inhibition of the TNF Signaling Pathway

open access: yesJournal of Medical Virology, Volume 97, Issue 1, January 2025.
ABSTRACT The two most clinically important members of the flavivirus genus, Zika virus (ZIKV) and dengue virus (DENV) pose a significant public health challenge. They cause a range of diseases in humans, from hemorrhagic to neurological manifestations, leading to economic and social burden worldwide.
Thamil Vaani Komarasamy   +4 more
wiley   +1 more source

In‐host modeling of dengue virus and non‐structural protein 1 and the effects of ivermectin in patients with acute dengue fever

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 13, Issue 12, Page 2196-2209, December 2024.
Abstract The increased incidence of dengue poses a substantially global public health challenge. There are no approved antiviral drugs to treat dengue infections. Ivermectin, an old anti‐parasitic drug, had no effect on dengue viremia, but reduced the dengue non‐structural protein 1 (NS1) in a clinical trial.
Junjie Ding   +15 more
wiley   +1 more source

Dengue fever in hyperglycemic patients: an emerging public health concern demanding eyes on the effective management strategies

open access: yesHealth Science Reports, Volume 7, Issue 10, October 2024.
Abstract Background and aims Hyperglycemia, also known as diabetes, is a metabolic disorder characterized by elevated levels of glucose in the bloodstream. It can lead to the prolonged dysfunction, injury, and deterioration of several organs. In addition, dengue is a viral illness transmitted by mosquitoes that has reached epidemic proportions ...
Shandipon Roy Shawon   +4 more
wiley   +1 more source

Vaccine process technology—A decade of progress

open access: yesBiotechnology and Bioengineering, Volume 121, Issue 9, Page 2604-2635, September 2024.
Abstract In the past decade, new approaches to the discovery and development of vaccines have transformed the field. Advances during the COVID‐19 pandemic allowed the production of billions of vaccine doses per year using novel platforms such as messenger RNA and viral vectors.
Barry Buckland   +8 more
wiley   +1 more source

IMMUNOGENICITY OF THE CYD-TDV VACCINE IN CHILDREN AND ADOLESCENTS: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS

open access: yesBrazilian Journal of Infectious Diseases
Introduction: Dengue is an arboviral disease prevalent in tropical regions. CYD-TDV (Dengvaxia®) is the first licensed vaccine, indicated for seropositive individuals.
Nicoly Fiorese Andrade   +5 more
doaj   +1 more source

A Review on Dengue Vaccine Development

open access: yesVaccines, 2020
Dengue virus (DENV) has become a global health threat with about half of the world’s population at risk of infection. Although the disease caused by DENV is self-limiting in the first infection, the antibody-dependent enhancement (ADE) effect ...
Sheng-Qun Deng   +5 more
doaj   +1 more source

Optimal Control of a Dengue-Dengvaxia Model: Comparison Between Vaccination and Vector Control

open access: yesComputational and Mathematical Biophysics, 2021
Dengue is the most common mosquito-borne viral infection transmitted disease. It is due to the four types of viruses (DENV-1, DENV-2, DENV-3, DENV-4), which transmit through the bite of infected Aedes aegypti and Aedes albopictus female mosquitoes during
Mentuda Cheryl Q.
doaj   +1 more source

YF17D‐based vaccines – standing on the shoulders of a giant

open access: yesEuropean Journal of Immunology, Volume 54, Issue 5, May 2024.
Graphical Abstract: Live‐attenuated yellow fever vaccine (YF17D) has emerged as platform to develop prophylactic and therapeutic vaccines against infectious diseases and cancer. In this review, we summarize the unique polyfunctional immunity endowed by original YF17D, and the progress and challenges of recombinant YF17D‐based vaccines for unmet medical
Lorena Sanchez‐Felipe   +4 more
wiley   +1 more source

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