Quantification of the lung cancer tumor marker CYFRA 21-1 using protein precipitation, immunoaffinity bottom-up LC-MS/MS [PDF]
Numerous studies have proven the potential of cytokeratin 19 fragment 21-1 (CYFRA 21-1) detection in the (early) diagnosis and treatment monitoring of non-small cell lung cancer (NSCLC). Conventional immunoassays for CYFRA 21-1 quantification are however
Broeren, Maarten A.C. +6 more
core +1 more source
Retracted: Effects of Bevacizumab Combined with Chemotherapy on CT, CyFRA21-1, and ProGRP and Prognosis of Lung Cancer Patients under Nursing Intervention. [PDF]
Comput Math Methods Med, 2023 Methods In Medicine CAM.
europepmc +1 more source
联合检测血清SCC CYFRA21-1 NSE对肺癌的诊断价值
Zhongguo shiyan zhenduanxue, 2010 目的探讨血清肿瘤相关因子鳞状细胞癌相关抗原（SCC）、细胞角蛋白19片段（CYFRA21-1）、神经元特异性烯醇化酶（NSE）联合检测对肺癌的诊断价值及临床意义。方法 174例肺癌患者、60名肺部良性肿瘤患者及60名正常人进行血清SCC、CYFRA21-1、NSE水平检测,比较三组患者血清SCC、CYFRA21-1、NSE表达差异及不同病理类型肺癌患者血清SCC、CYFRA21-1、NSE表达差异。结果肺癌患者血清SCC、CYFRA21-1、NSE水平高于正常人及肺部良性肿瘤患者 ...
杨琳红, 王岷, 陈文靖, 焦其英
doaj
Minilaparotomy, Cyfra21-1, and Other Predicting Factors for Suboptimal Cytoreductive Surgery in Advanced Epithelial Ovarian Cancer: A Pilot Study. [PDF]
Asian Pac J Cancer Prev, 2022 Nantasupha C +2 more
europepmc +1 more source
Zhongguo shiyan zhenduanxue, 2011 目的观察非小细胞肺癌（NSCLC）放疗前后血清CEA、CYFRA21-1、NSE的变化,探讨血清肿瘤标记物的改变能否用于评价放疗疗效。方法选取58例接受放射治疗的非小细胞肺癌病例（其中22例为局部晚期患者行胸部原发灶放疗,12例行骨转移放疗,24例行脑转移放疗）,所选病例放疗前肿瘤标记物均高于正常参考值,分别记录放疗前与放疗后血清CEA、NSE、CYFRA21-1的数值,并用Wilcoxon秩检验进行统计分析,以p0.05）。结论血清CEA、CYFRA21-1 ...
张国云, 周春宇, 刘晓岚
doaj
Frontiers in OncologyBackgroundOur study aimed to develop a nomogram incorporating cytokeratin fragment antigen 21–1 (CYFRA21–1) to assist in differentiating between patients with intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC).MethodsA total of 487 ...
Yuan-Yuan Liu +4 more
doaj +1 more source
Development and validation of reassigned CEA, CYFRA21-1 and NSE-based models for lung cancer diagnosis and prognosis prediction. [PDF]
BMC Cancer, 2022 Yuan J +13 more
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CYFRA 21-1 in Non-Small Cell Lung Cancer – Standardisation and Application during Diagnosis [PDF]
, 2008 There is no ideal tumour marker at present. The clinical application of CYFRA 21-1 is possible once a thorough standardisation process is carried out. Standardisation is achieved by determining the reference range in asymptomatic population, benign and ...
Ana Franjević +4 more
core +1 more source
Ultrasensitive and Efficient CYFRA21-1 Nanosensor Empowered by CRISPR/Cas12a Nanopipette Technology
Journal of The Electrochemical SocietyThe abnormal expression of CYFRA21-1 is closely related to the development of non-small cell lung cancer (NSCLC), making its detection crucial for early diagnosis. In this study, we successfully constructed an electrochemical sensor based on nanopipettes and CRISPR/Cas12a for the detection of CYFRA21-1.
Yilin Shi +4 more
openaire +1 more source
Retracted: Observation of the Curative Effect of Acupuncture for Tonifying Kidney and Removing Blood Stasis Combined with Radiofrequency Surgery in Patients with NSCLC and the Diagnostic Efficacy of Combined Detection of NTx, BGP, and CYFRA21-1 in the Occurrence of Bone Metastases. [PDF]
Contrast Media Mol Imaging, 2023 Imaging CMM.
europepmc +1 more source