联合检测血清SCC CYFRA21-1 NSE对肺癌的诊断价值
Zhongguo shiyan zhenduanxue, 2010 目的探讨血清肿瘤相关因子鳞状细胞癌相关抗原（SCC）、细胞角蛋白19片段（CYFRA21-1）、神经元特异性烯醇化酶（NSE）联合检测对肺癌的诊断价值及临床意义。方法 174例肺癌患者、60名肺部良性肿瘤患者及60名正常人进行血清SCC、CYFRA21-1、NSE水平检测,比较三组患者血清SCC、CYFRA21-1、NSE表达差异及不同病理类型肺癌患者血清SCC、CYFRA21-1、NSE表达差异。结果肺癌患者血清SCC、CYFRA21-1、NSE水平高于正常人及肺部良性肿瘤患者 ...
杨琳红, 王岷, 陈文靖, 焦其英
doaj
Frontiers in MedicineObjectiveThis study aimed to assess the clinical value of cytokeratin 19 fragment (CYFRA21-1) and its correlation with Krebs von den Lungen-6 (KL-6) in stratifying the severity of rheumatoid arthritis-associated interstitial lung disease (RA-ILD ...
Jingjing Yin +5 more
doaj +1 more source
Minilaparotomy, Cyfra21-1, and Other Predicting Factors for Suboptimal Cytoreductive Surgery in Advanced Epithelial Ovarian Cancer: A Pilot Study. [PDF]
Asian Pac J Cancer Prev, 2022 Nantasupha C +2 more
europepmc +1 more source
Quantification of the lung cancer tumor marker CYFRA 21-1 using protein precipitation, immunoaffinity bottom-up LC-MS/MS [PDF]
Numerous studies have proven the potential of cytokeratin 19 fragment 21-1 (CYFRA 21-1) detection in the (early) diagnosis and treatment monitoring of non-small cell lung cancer (NSCLC). Conventional immunoassays for CYFRA 21-1 quantification are however
Broeren, Maarten A.C. +6 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2011 目的观察非小细胞肺癌（NSCLC）放疗前后血清CEA、CYFRA21-1、NSE的变化,探讨血清肿瘤标记物的改变能否用于评价放疗疗效。方法选取58例接受放射治疗的非小细胞肺癌病例（其中22例为局部晚期患者行胸部原发灶放疗,12例行骨转移放疗,24例行脑转移放疗）,所选病例放疗前肿瘤标记物均高于正常参考值,分别记录放疗前与放疗后血清CEA、NSE、CYFRA21-1的数值,并用Wilcoxon秩检验进行统计分析,以p0.05）。结论血清CEA、CYFRA21-1 ...
张国云, 周春宇, 刘晓岚
doaj
Development and validation of reassigned CEA, CYFRA21-1 and NSE-based models for lung cancer diagnosis and prognosis prediction. [PDF]
BMC Cancer, 2022 Yuan J +13 more
europepmc +1 more source
CYFRA 21-1 in Non-Small Cell Lung Cancer – Standardisation and Application during Diagnosis [PDF]
, 2008 There is no ideal tumour marker at present. The clinical application of CYFRA 21-1 is possible once a thorough standardisation process is carried out. Standardisation is achieved by determining the reference range in asymptomatic population, benign and ...
Ana Franjević +4 more
core +1 more source
Ultrasensitive and Efficient CYFRA21-1 Nanosensor Empowered by CRISPR/Cas12a Nanopipette Technology
Journal of The Electrochemical SocietyThe abnormal expression of CYFRA21-1 is closely related to the development of non-small cell lung cancer (NSCLC), making its detection crucial for early diagnosis. In this study, we successfully constructed an electrochemical sensor based on nanopipettes and CRISPR/Cas12a for the detection of CYFRA21-1.
Yilin Shi +4 more
openaire +1 more source
Frontiers in OncologyBackgroundOur study aimed to develop a nomogram incorporating cytokeratin fragment antigen 21–1 (CYFRA21–1) to assist in differentiating between patients with intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC).MethodsA total of 487 ...
Yuan-Yuan Liu +4 more
doaj +1 more source
The relationship between glasgow prognostic score and serum tumor markers in patients with advanced non-small cell lung cancer [PDF]
, 2015 core +1 more source