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Rapid and quantitative detection of urinary Cyfra21-1 using fluorescent nanosphere-based immunochromatographic test strip for diagnosis and prognostic monitoring of bladder cancer

open access: yesArtificial Cells, Nanomedicine and Biotechnology, 2019
Bladder cancer is a common malignant tumour with high recurrence rate. Cytokeratin 19 fragments (Cyfra21-1) in urine has been regarded as a promising biomarker for the prognosis and diagnosis of bladder cancer due to the relevance of its high urinary ...
Zhiyong Li, Song Wu, Qifang Lei
exaly   +2 more sources
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Perfluorosulfonic acid polymer based eATRP for ultrasensitive detection of CYFRA21-1 DNA

Analytical Methods, 2020
The sensitive detection of biomarker cytokeratin fragment antigen 21-1 (CYFRA21-1) is crucial for early diagnosis and screening of non-small cell lung cancer (NSCLC).
Kai Hu   +6 more
openaire   +2 more sources

Serum Cytokeratin 19 Fragment (CYFRA21-1) as a Prognostic Factor in Intrahepatic Cholangiocarcinoma

Annals of Surgical Oncology, 2007
A high serum cytokeratin 19 fragment (CYFRA21-1) concentration in patients with various cancers is associated with poor prognosis. This study aimed to establish the clinical significance of preoperative serum CYFRA21-1 in patients with intrahepatic cholangiocarcinoma.CYFRA21-1, carcinoembryonic antigen (CEA), and carbohydrate antigen (CA) 19-9 ...
Takahiro, Uenishi   +7 more
openaire   +2 more sources

[Clinical usefulness of serum CYFRA21-1 in colorectal cancer].

Gan to kagaku ryoho. Cancer & chemotherapy, 1996
Serum CYFRA21-1 levels were studied in 127 cases of colorectal cancer. The positive rates for serum CYFRA21-1 were 34.6% in primary colorectal cancer. There was a significant correlation between the positive rates of serum CYFRA21-1 and liver metastases, peritoneal dissemination, lymph node metastases, or clinical stage.
T, Miyashita   +10 more
openaire   +1 more source

SERUM CYTOKERATIN-19 MEASURED BY CYFRA21-1 ASSAY IN PATIENTS WITH GASTROINTESTINAL AND GYNECOLOGIC MALIGNANCY

International Journal of Oncology, 1994
The serum fragment of cytokeratin 19 was measured in 130 patients with gastrointestinal, breast and gynecologic cancer and 62 patients with benign disease using CYFRA21-1 immunoradiometric assay. Patients with advanced cancer showed the highest level of serum CYFRA21-1.
H, Sakahara   +6 more
openaire   +2 more sources

Combination of serum miRNAs with Cyfra21-1 for the diagnosis of non-small cell lung cancer

Cancer Letters, 2015
In this study, we screened 381 miRNAs by RT-qPCR in serum samples of 44 NSCLC patients and 22 healthy individuals to identify altered miRNAs, and validated the results in a training and test cohorts with 300 serum samples (178 NSCLC and 122 healthy individuals).
Chengcheng, Zhou   +9 more
openaire   +2 more sources

CYFRA21-1 can predict the sensitivity to chemoradiotherapy of non-small-cell lung carcinoma

Biomarkers, 2010
The increasing panel of systemic therapies enables the individual management of lung cancer patients, even in advanced stages. However, predictive tools indicating the efficacy of chemoradiotherapy (CRT) are badly needed.To determine the tumour markers for predicting the therapeutic effect in non-small-cell lung carcinoma (NSCLC) patients treated with ...
Juan, Wang   +6 more
openaire   +2 more sources

[Diagnostic value of combined detection of CYFRA21-1 and TSGF in nasopharyngeal carcinoma].

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 2006
To study the diagnostic value of cytokeraetin 19 fragment (CYFRA21-1) and tumor supplied group factors (TSGF) in nasopharyngeal carcinoma (NPC).Serum levels of CYFRA21-1 and TSGF in 82 patients with NPC, 25 patients with benign nasopharyngeal disease and 50 normal controls were measured by electrochemiluminescence immuno-assay.The levels of CYFRA21-1 ...
Lingsha, Huang   +2 more
openaire   +1 more source

[Evaluation of a cytokeratin 19 assay kit "BALL ELSA CYFRA21-1"].

Kaku igaku. The Japanese journal of nuclear medicine, 1994
We evaluated "BALL ELSA CYFRA21-1" kit, an immunoradiometric assay kit for cytokeratin 19. Monoclonal antibodies KS19-1 and BM19-21 are used for immunoadsorbent and indicator, respectively. There was no problems in reproducibility, dilution test and recovery test. Minimum detectable concentration was 0.42 ng/ml.
H, Sakahara   +7 more
openaire   +1 more source

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