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Susceptibility of Japanese Cyprininae fish species to cyprinid herpesvirus 2 (CyHV-2)

Veterinary Microbiology, 2014
Cyprinid herpesvirus 2 (CyHV-2) is known as the causative agent of herpesviral haematopoietic necrosis (HVHN) of goldfish (Carassius auratus). Recently, the virus has also been detected from Prussian carp (C. gibelio) and crucian carp (C. carassius) from European and Asian countries.
Takafumi, Ito, Yukio, Maeno
openaire   +2 more sources

Recombinant baculovirus BacCarassius-D4ORFs has potential as a live vector vaccine against CyHV-2

Fish & Shellfish Immunology, 2019
Cyprinid herpesvirus II (CyHV-2) is highly contagious and pathogenic to Carassius auratus gibelio (gibel carp), causing enormous economic losses in aquaculture in Yancheng city, Jiangsu province, China; however, to date, there is no effective way to protect C. auratus gibelio from CyHV-2 infection.
Kun Li   +13 more
openaire   +2 more sources

Reactivation of cyprinid herpesvirus 2 (CyHV-2) in asymptomatic surviving goldfish Carassius auratus (L.) under immunosuppression

Fish & Shellfish Immunology, 2020
Cyprinid herpesvirus 2 (CyHV-2) is a highly contagious pathogen of goldfish (Carassius auratus) and Prussian carp (Carassius auratus gibelio) causing herpesviral hematopoietic necrosis. Our previous study revealed that CyHV-2 can persistently infect the kidney and spleen of goldfish that recovered from a primary infection.
Chang, Wei   +5 more
openaire   +2 more sources

Evaluation of candidate reference genes for quantitative RTqPCR analysis in goldfish (Carassius auratus L.) in healthy and CyHV-2 infected fish

Veterinary Immunology and Immunopathology, 2021
The accuracy of quantitative real time PCR (RTqPCR) can be attained only when a suitable reference gene is used. The gene expression for a particular gene may vary within different cells at different conditions. Hence, the suitability and stability of various potential reference genes have to be determined for expression studies. In this study, we have
Arathi Dharmaratnam   +4 more
openaire   +2 more sources

Type I interferon responses of common carp strains with different levels of resistance to koi herpesvirus disease during infection with CyHV-3 or SVCV [PDF]

open access: yesFish and Shellfish Immunology, 2019
Carp from breeding strains with different genetic background present diverse levels of resistance to viral pathogens. Carp strains of Asian origin, currently being treated as Cyprinus rubrofuscus L., especially Amur wild carp (AS), were proven to be more
Magdalena Stachnik   +2 more
exaly   +2 more sources

Effects of experimentally induced infections of goldfish Carassius auratus with cyprinid herpesvirus 2 (CyHV-2) at various water temperatures

Diseases of Aquatic Organisms, 2014
In this study, we examined the influence of water temperature on the development of herpesviral haematopoietic necrosis (HVHN) in goldfish Carassius auratus after experimentally induced infection with cyprinid herpesvirus 2 (CyHV-2). In Expt 1, Ryukin goldfish were infected with CyHV-2 by intraperitoneal injection and maintained at 4 different water ...
Takafumi, Ito, Yukio, Maeno
openaire   +2 more sources

Expression pattern and regulatory network of gibel carp (Carassius gibelio) miRNAs and their putative target genes in response to CyHV-2 infection

Aquaculture, 2020
Abstract MicroRNAs (miRNAs) are endogenous small non-coding RNAs that are post-transcriptional regulators. They not only play vital roles in a variety of biological processes, but also regulate the process of viral infection. Cyprinid herpesvirus 2 (CyHV-2), a pathogen of Gibel carp (Carassius gibelio), can induce herpesviral hematopoietic necrosis ...
Yunshan Zhang   +16 more
openaire   +1 more source

Histopathology and ultrastructural pathology of cyprinid herpesvirus II (CyHV-2) infection in gibel carp, Carassius auratus gibelio

Wuhan University Journal of Natural Sciences, 2015
Cyprinid herpesvirus II (CyHV-2) infection is identified in cultured gibel carp, Carassius auratus gibelio, with high mortality in China in recent years. Histological pathology includes acute hepatocellular necrosis, splenic necrosis, kidney necrosis, hyperplasia of the secondary lamellae with focal necrosis. Acute necrotic myocarditis and granulocytes
Nan Jiang   +6 more
openaire   +1 more source

Cyprinid herpesvirus 2 (CyHV-2) ORF67 inhibits IFN expression by competitively obstructing STING phosphorylation

Fish & Shellfish Immunology
Cyprinid herpesvirus 2 (CyHV-2) caused hematopoietic necrosis in crucian carp (Carassius auratus) has resulted in huge economic losses to the carp aquaculture. Interferon (IFN) response serves as a crucial line of defense for fish against CyHV-2 infection; however, CyHV-2 frequently overcomes this defense, resulting in damage and even substantial ...
Bao-Jie Cui   +9 more
openaire   +2 more sources

CyHV-2 infection triggers mitochondrial-mediated apoptosis in GiCF cells by upregulating the pro-apoptotic gene ccBAX

Fish & Shellfish Immunology
Apoptosis is a physiological cell death phenomenon, representing one of the fundamental physiological mechanisms for maintaining homeostasis in living organisms. Previous studies have observed typical apoptotic features in Carassius auratus gibelio caudal fin cell (GiCF) infected with Cyprinid herpesvirus 2 (CyHV-2), and found a significant up ...
Wenjie Cheng   +7 more
openaire   +2 more sources

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