Immunomodulatory Effects of Pure Cylindrospermopsin in Rats Orally Exposed for 28 Days
Toxins, 2022 Cylindrospermopsin (CYN) is a ubiquitous cyanotoxin showing increasing incidence worldwide. CYN has been classified as a cytotoxin and, among its toxic effects, its immunotoxicity is scarcely studied.
Leticia Diez-Quijada +6 more
doaj +2 more sources
Lettuce (Lactuca sativa L.) leaf-proteome profiles after exposure to cylindrospermopsin and a microcystin-LR/cylindrospermopsin mixture: A concentration-dependent response [PDF]
, 2014 The intensification of agricultural productivity is an important challenge worldwide. However, environmental stressors can provide challenges to this intensification. The progressive occurrence of the cyanotoxins cylindrospermopsin (CYN) and microcystin-
Marisa Freitas +6 more
openalex +4 more sources
Immunomodulatory Effects of Cylindrospermopsin in Human T Cells and Monocytes
Toxins, 2023 Cylindrospermopsin (CYN) is a cyanotoxin with an increasing occurrence, and therefore it is important to elucidate its toxicity profile. CYN has been classified as a cytotoxin, although the scientific literature has already revealed that it affects a ...
A. Casas-Rodríguez +4 more
semanticscholar +5 more sources
New Method for Simultaneous Determination of Microcystins and Cylindrospermopsin in Vegetable Matrices by SPE-UPLC-MS/MS [PDF]
Toxins, 2018 Cyanotoxins are a large group of noxious metabolites with different chemical structure and mechanisms of action, with a worldwide distribution, producing effects in animals, humans, and crop plants.
Leticia Díez-Quijada +7 more
doaj +3 more sources
Influence of Glycine and Arginine on Cylindrospermopsin Production and aoa Gene Expression in Aphanizomenon ovalisporum [PDF]
Toxins, 2017 Arginine (Arg) and glycine (Gly) seem to be the only substrates accepted by the amidinotransferase that catalyze the first step of the synthesis pathway of the cyanotoxin cylindrospermopsin (CYN), leading to guanidinoacetate (GAA).
Ángel Barón-Sola +2 more
doaj +2 more sources
Evaluation of Genotoxic and Hemolytic Effects of Aphanizomenon flos-aquae and Microcystis aeruginosa Biomass Extracts on Human Blood Cells In Vitro [PDF]
MicroorganismsThis study explores the in vitro effects of cyanotoxins from the methanolic extract of the cyanobacteria Aphanizomenon flos-aquae and Microcystis aeruginosa on human blood cells, with samples drawn from the Gruža reservoir in Serbia. These cyanobacteria,
Nevena B. Đorđević +6 more
doaj +2 more sources
Toxins, 2022 Microcystins (MCs) and cylindrospermopsin (CYN), although classified as hepatotoxins and cytotoxins, respectively, have been shown to also induce toxic effects in many other systems and organs.
Antonio Casas-Rodriguez +2 more
doaj +2 more sources
Molecular Screening for Cyanobacteria and Their Cyanotoxin Potential in Diverse Habitats [PDF]
ToxinsCyanobacteria are adaptable and dominant organisms that exist in many harsh and extreme environments due to their great ecological tolerance. They produce various secondary metabolites, including cyanotoxins.
Maša Jablonska +5 more
doaj +2 more sources
Microcystin-LR and Cylindrospermopsin Induced Alterations in Chromatin Organization of Plant Cells [PDF]
Marine Drugs, 2013 Cyanobacteria produce metabolites with diverse bioactivities, structures and pharmacological properties. The effects of microcystins (MCYs), a family of peptide type protein-phosphatase inhibitors and cylindrospermopsin (CYN), an alkaloid type of protein
Gábor Vasas +2 more
doaj +3 more sources
Cytotoxic effects of cylindrospermopsin in mitotic and non-mitotic Vicia faba cells [PDF]
, 2014 K
Tamás Garda +7 more
openalex +4 more sources