Results 11 to 20 of about 4,091 (215)

New Data on Cylindrospermopsin Toxicity [PDF]

Toxins, 2021
Cylindrospermopsin (CYN) is a widely spread cyanotoxin that can occur in fresh water and food. This research aims to investigate CYN toxicity by studying the effects of drinking 0.25 nM of CYN-contaminated water from a natural source, and of the direct ...
Mariela Chichova, Oskan Tasinov, Milena Shkodrova, Milena Mishonova, Iliyana Sazdova, Bilyana Ilieva, Dilyana Doncheva-Stoimenova, Yoana Kiselova-Kaneva, Neli Raikova, Blagoy Uzunov, Diana Ivanova, Hristo Gagov   +11 more
doaj   +3 more sources

Occurrence and Diversity of Cyanotoxins and Retinoid Compounds in Antarctic Microbial Mats: Evidence From James Ross Island. [PDF]

Environ Microbiol Rep
Occurrence and distribution of cyanotoxins and retinoids across different Antarctic ecosystems at James Ross Island. These ecosystems harbour diverse microbial communities dominated by autotrophic cyanobacteria and algae, which can produce hazardous compounds for animals.
Sehnal L, Bláhová L, Smutná M, Mikeš O, Babica P, Hilscherová K.   +5 more
europepmc   +2 more sources

Subchronic Oral Cylindrospermopsin Exposure Alters the Host Gut Microbiome and Is Associated with Progressive Hepatic Inflammation, Stellate Cell Activation, and Mild Fibrosis in a Preclinical Study

Toxins, 2022
Epidemiological studies have reported a strong association between liver injury and incidences of hepatocellular carcinoma in sections of humans globally.
Punnag Saha, Macayla Upright, Dipro Bose, Subhajit Roy, Ayushi Trivedi, Madhura More, Geoff I. Scott, Bryan W. Brooks, Saurabh Chatterjee   +8 more
doaj   +1 more source

Nutrient-driven regulation of saxitoxin gene expression and toxin production in Raphidiopsis raciborskii (Cyanobacteria). [PDF]

J Phycol
Abstract Raphidiopsis raciborskii is a diazotrophic cyanobacterium, globally distributed in aquatic environments and known for forming toxic blooms, thereby affecting ecosystem services. South American strains are producers of saxitoxins, potent neurotoxins harmful to humans and animals.
Zare M, Barçante B, Pimentel JDSM, Giani A.   +3 more
europepmc   +2 more sources

Nutrient Regulation of Relative Dominance of Cylindrospermopsin-Producing and Non-cylindrospermopsin-Producing Raphidiopsis raciborskii [PDF]

Frontiers in Microbiology, 2021
Raphidiopsis raciborskii (previously Cylindrospermopsis raciborskii) can produce cylindrospermopsin (CYN) which is of great concern due to its considerable toxicity to human and animals. Its CYN-producing (toxic) and non-CYN-producing (non-toxic) strains co-exist commonly in natural water bodies, while how their relative dominance is regulated has not ...
Lamei Lei, Minting Lei, Nan Cheng, Zhijiang Chen, Lijuan Xiao, Bo-ping Han, Qiuqi Lin   +6 more
openaire   +3 more sources

Genome analysis of Pseudomonas sp. OF001 and Rubrivivax sp. A210 suggests multicopper oxidases catalyze manganese oxidation required for cylindrospermopsin transformation

BMC Genomics, 2021
Background Cylindrospermopsin is a highly persistent cyanobacterial secondary metabolite toxic to humans and other living organisms. Strain OF001 and A210 are manganese-oxidizing bacteria (MOB) able to transform cylindrospermopsin during the oxidation of
Erika Berenice Martínez-Ruiz, Myriel Cooper, Jimena Barrero-Canosa, Mindia A. S. Haryono, Irina Bessarab, Rohan B. H. Williams, Ulrich Szewzyk   +6 more
doaj   +1 more source

Local-scale impacts of water hyacinth on water quality in a hypereutrophic lake

Frontiers in Water, 2023
Increased nutrient concentrations have been linked to water quality impairments across the world. In Lake Victoria, the second largest freshwater lake in the world, decades of eutrophication have challenged water quality management and led to conditions ...
Jessica R. Corman, Amber Roegner, Amber Roegner, Zachary Ogari, Todd R. Miller, Christopher M. Aura   +5 more
doaj   +1 more source

Cytotoxicity and Effects on the Synapsis Induced by Pure Cylindrospermopsin in an E17 Embryonic Murine Primary Neuronal Culture in a Concentration- and Time-Dependent Manner

Toxins, 2022
Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Due to its capacity to exert damage at different levels of the organism, it is considered a cytotoxin.
María G. Hinojosa, Ana I. Prieto, Clara Muñoz-Castro, María V. Sánchez-Mico, Javier Vitorica, Ana M. Cameán, Ángeles Jos   +6 more
doaj   +1 more source

Alternative Isolation Protocol for Desulfo and Zwitterionic Cylindrospermopsin Alkaloids and Comparison of Their Toxicity in HepG2 Cells

Molecules, 2020
The term cylindrospermopsins (CYNs) refers to a structurally related class of cyanobacterial metabolites comprised of a tricyclic guanidine group and a hydroxymethyluracil moiety. Most reports in environmental aquatic samples refer to cylindrospermopsin (
Carlos González-Blanco, Felipe Augusto Dörr, Renata Albuquerque, Janice Onuki, Ernani Pinto   +4 more
doaj   +1 more source

Environmental Exposure to Cyanobacteria Hepatotoxins in a Pacific Island Community: A Cross-Sectional Assessment

Microorganisms, 2022
(1) Background: Cyanobacteria produce a wide range of secondary metabolites, including tumor-promoting hepatotoxins. We recently reported evidence of an independent association between oral cyanobacteria and hepatocellular carcinoma in a U.S. population.
Brenda Y. Hernandez, Jason Biggs, Xuemei Zhu, Patrick Sotto, Michelle Nagata, Ana Joy Pacilan Mendez, Yvette Paulino   +6 more
doaj   +1 more source