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Biosynthesis of Saxitoxin in Marine Dinoflagellates: An Omics Perspective

open access: yesMarine Drugs, 2020
Saxitoxin is an alkaloid neurotoxin originally isolated from the clam Saxidomus giganteus in 1957. This group of neurotoxins is produced by several species of freshwater cyanobacteria and marine dinoflagellates.
Noor Idayu Tahir   +2 more
exaly   +4 more sources

Evolution and Distribution of Saxitoxin Biosynthesis in Dinoflagellates [PDF]

open access: yesMarine Drugs, 2013
Numerous species of marine dinoflagellates synthesize the potent environmental neurotoxic alkaloid, saxitoxin, the agent of the human illness, paralytic shellfish poisoning.
Shauna Murray   +2 more
exaly   +4 more sources

Surface Plasmon Spectroscopic Detection of Saxitoxin

open access: yesSensors, 2007
For the surface-optoelectronic study of Saxitoxin sensing, we fabricated self-assembled calix[4]arene derivative monolayers as the recognition-functional interfaces ona gold surface.
Jong H Kim, Won G An, Jaebeom Lee
exaly   +4 more sources

Temperature Influences the Production and Transport of Saxitoxin and the Expression of sxt Genes in the Cyanobacterium Aphanizomenon gracile [PDF]

open access: yesToxins, 2017
The cyanobacterium Aphanizomenon gracile is the most widely distributed producer of the potent neurotoxin saxitoxin in freshwaters. In this work, total and extracellular saxitoxin and the transcriptional response of three genes linked to saxitoxin ...
Samuel Cirés   +2 more
exaly   +4 more sources

Discovery of nuclear-encoded genes for the neurotoxin saxitoxin in dinoflagellates. [PDF]

open access: yesPLoS ONE, 2011
Saxitoxin is a potent neurotoxin that occurs in aquatic environments worldwide. Ingestion of vector species can lead to paralytic shellfish poisoning, a severe human illness that may lead to paralysis and death.
Anke Stüken   +5 more
doaj   +3 more sources

A Robust Electrochemical Aptasensor Based on a AuNP/Chitosan Conductive Network for Saxitoxin Detection in Freshwater Samples [PDF]

open access: yesBiosensors
Saxitoxin (STX) is a highly potent marine biotoxin, and trace contamination in aquatic environments can pose serious risks to human health. Therefore, reliable detection of low-concentration STX is crucial for water safety monitoring.
Luyang Zhang   +4 more
doaj   +2 more sources

Improved Accuracy of Saxitoxin Measurement Using an Optimized Enzyme-Linked Immunosorbent Assay

open access: yesToxins, 2019
Paralytic shellfish poisoning (PSP) is precipitated by a family of toxins produced by harmful algae, which are consumed by filter-feeding and commercially popular shellfish.
Wayne Litaker, Ransom Hardison
exaly   +3 more sources

An Overview on the Marine Neurotoxin, Saxitoxin: Genetics, Molecular Targets, Methods of Detection and Ecological Functions

open access: yesMarine Drugs, 2013
Marine neurotoxins are natural products produced by phytoplankton and select species of invertebrates and fish. These compounds interact with voltage-gated sodium, potassium and calcium channels and modulate the flux of these ions into various cell types.
Kathleen Cusick
exaly   +3 more sources

Rapid Detection of Saxitoxin Using a Nucleic Acid Aptamer Biosensor Based on Graphene Oxide as a Fluorescence Quencher [PDF]

open access: yesToxins
Saxitoxin (STX) is a toxin with paralyzing and lethal properties, necessitating the development of a simple analytical method. This study developed a nucleic acid aptamer biosensor using graphene oxide (GO) as a fluorescence quencher for STX detection ...
Yi Jiao   +8 more
doaj   +2 more sources

Microfluidic Flow Injection Immunoassay System for Algal Toxins Determination: A Case of Study

open access: yesFrontiers in Chemistry, 2021
A novel flow injection microfluidic immunoassay system for continuous monitoring of saxitoxin, a lethal biotoxin, in seawater samples is presented in this article.
Lorenzo Celio   +9 more
doaj   +1 more source

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