Results 11 to 20 of about 4,671 (208)

An Overview on the Marine Neurotoxin, Saxitoxin: Genetics, Molecular Targets, Methods of Detection and Ecological Functions

Marine Drugs, 2013
Marine neurotoxins are natural products produced by phytoplankton and select species of invertebrates and fish. These compounds interact with voltage-gated sodium, potassium and calcium channels and modulate the flux of these ions into various cell types.
Kathleen D Cusick
exaly   +3 more sources

Occurrence and Diversity of Cyanotoxins and Retinoid Compounds in Antarctic Microbial Mats: Evidence From James Ross Island. [PDF]

Environ Microbiol Rep
Occurrence and distribution of cyanotoxins and retinoids across different Antarctic ecosystems at James Ross Island. These ecosystems harbour diverse microbial communities dominated by autotrophic cyanobacteria and algae, which can produce hazardous compounds for animals.
Sehnal L, Bláhová L, Smutná M, Mikeš O, Babica P, Hilscherová K.   +5 more
europepmc   +2 more sources

Phytoplankton growth and potential cyanotoxin production differ in response to nitrogen and phosphorus amendments in late summer communities from Kabetogama Lake (Minnesota, United States). [PDF]

J Phycol
Abstract Cyanotoxins such as microcystin (MC), cylindrospermopsin, and saxitoxin are secondary metabolites that are rich in nitrogen (N). Most cyanobacteria grow best on reduced inorganic N (ammonium, NH4), but when NH4 is absent, cyanobacteria can activate physiological pathways to process other N forms (e.g., nitrate; NO3).
Larson JH, Maki RP, Bailey SW, Christensen VG, Loftin KA, Stelzer EA, Smith JC, McWhorter SA.   +7 more
europepmc   +2 more sources

Neurotoxic Alkaloids: Saxitoxin and Its Analogs

Marine Drugs, 2010
Saxitoxin (STX) and its 57 analogs are a broad group of natural neurotoxic alkaloids, commonly known as the paralytic shellfish toxins (PSTs). PSTs are the causative agents of paralytic shellfish poisoning (PSP) and are mostly associated with marine ...
Troco K. Mihali, Michelle C. Moffitt, Brett A. Neilan, Maria Wiese, Paul M. D’Agostino   +4 more
doaj   +2 more sources

First report of saxitoxin in octopi

Toxicon, 2004
We report for the first time, the presence of saxitoxin (STX) in a common cephalopod, Octopus (Abdopus) sp. 5, collected from Cooke Point on the northern coastline of Western Australia. Sodium channel and saxiphilin based radio-receptor assays detected saxitoxin-like binding in octopi extracts.
Robertson, Alison, Stirling, David, Robillot, Cedric, Llewellyn, Lyndon, Negri, Andrew   +4 more
openaire   +4 more sources

Nutrient-driven regulation of saxitoxin gene expression and toxin production in Raphidiopsis raciborskii (Cyanobacteria). [PDF]

J Phycol
Abstract Raphidiopsis raciborskii is a diazotrophic cyanobacterium, globally distributed in aquatic environments and known for forming toxic blooms, thereby affecting ecosystem services. South American strains are producers of saxitoxins, potent neurotoxins harmful to humans and animals.
Zare M, Barçante B, Pimentel JDSM, Giani A.   +3 more
europepmc   +2 more sources

Dataset of genome sequence, de novo assembly, and functional annotation of Ruegeria sp. (PBVC088), a marine bacterium associated with the toxin-producing harmful dinoflagellate, Pyrodinium bahamense var. compressum

Data in Brief, 2022
The dataset comprises a whole-genome sequence of Ruegeria sp. PBVC088, a symbiotic (Gram-negative) bacterium associated with Pyrodinium bahamense var.
Grace Joy Wei Lie Chin, Salley Venda Law, Kenneth Francis Rodrigues, Jaeyres Jani, Ann Anton   +4 more
doaj   +1 more source

Microfluidic Flow Injection Immunoassay System for Algal Toxins Determination: A Case of Study

Frontiers in Chemistry, 2021
A novel flow injection microfluidic immunoassay system for continuous monitoring of saxitoxin, a lethal biotoxin, in seawater samples is presented in this article.
Lorenzo Celio, Matteo Ottaviani, Rocco Cancelliere, Alessio Di Tinno, Alessio Di Tinno, Peter Panjan, Peter Panjan, Adama Marie Sesay, Adama Marie Sesay, Laura Micheli   +9 more
doaj   +1 more source

Insights into Alexandrium minutum Nutrient Acquisition, Metabolism and Saxitoxin Biosynthesis through Comprehensive Transcriptome Survey

Biology, 2021
The toxin-producing dinoflagellate Alexandrium minutum is responsible for the outbreaks of harmful algae bloom (HABs). It is a widely distributed species and is responsible for producing paralytic shellfish poisoning toxins.
Muhamad Afiq Akbar, Nurul Yuziana Mohd Yusof, Fathul Karim Sahrani, Gires Usup, Asmat Ahmad, Syarul Nataqain Baharum, Nor Azlan Nor Muhammad, Hamidun Bunawan   +7 more
doaj   +1 more source

Physiological Effects of Oxidative Stress Caused by Saxitoxin in the Nematode Caenorhabditis elegans

Marine Drugs, 2023
Saxitoxin (STX) causes high toxicity by blocking voltage-gated sodium channels, and it poses a major threat to marine ecosystems and human health worldwide.
Haiyan Wu, Balakrishnan Prithiviraj, Zhijun Tan   +2 more
doaj   +1 more source