Results 1 to 10 of about 11,247 (202)

Tetrodotoxin, an Extremely Potent Marine Neurotoxin: Distribution, Toxicity, Origin and Therapeutical Uses

Marine Drugs, 2015
Tetrodotoxin (TTX) is a potent neurotoxin responsible for many human intoxications and fatalities each year. The origin of TTX is unknown, but in the pufferfish, it seems to be produced by endosymbiotic bacteria that often seem to be passed down the ...
Jorge Lago, Ana G Cabado
exaly   +3 more sources

Behavioral and Chemical Ecology of Marine Organisms with Respect to Tetrodotoxin

Marine Drugs, 2010
The behavioral and chemical ecology of marine organisms that possess tetrodotoxin (TTX) has not been comprehensively reviewed in one work to date. The evidence for TTX as an antipredator defense, as venom, as a sex pheromone, and as an attractant for TTX-
Becky L. Williams
exaly   +3 more sources

Molecular Characterization of the Von Willebrand Factor Type D Domain of Vitellogenin from Takifugu flavidus

Marine Drugs, 2021
The von Willebrand factor type D (VWD) domain in vitellogenin has recently been found to bind tetrodotoxin. The way in which this protein domain associates with tetrodotoxin and participates in transporting tetrodotoxin in vivo remains unclear.
Kun Qiao, Caiyun Jiang, Min Xu, Bei Chen, Wenhui Qiu, Yongchang Su, Hua Hao, Zhiyong Lin, Shuilin Cai, Jie Su, Zhiyu Liu, Wenshu Huang   +11 more
doaj   +1 more source

Reversible cerebral vasoconstriction syndrome associated with tetrodotoxin poisoning: A case report

Journal of the American College of Emergency Physicians Open, 2021
An 81‐year‐old woman with a history of hypertension and Alzheimer's disease presented to the emergency department because of impaired consciousness. Physical examination revealed acute progressive generalized flaccid paralysis, hypertension, respiratory ...
Eiichi Kakehi, Makoto Matsumoto, Shohei Taniguchi, Yukinobu Akamatsu, Shigehisa Sakurai, Akane Hirotani, Takafumi Nozaki, Keisuke Shoji, Seiji Adachi, Kazuhiko Kotani, Masami Matsumura   +10 more
doaj   +1 more source

Natural Products in Polyclad Flatworms

Marine Drugs, 2021
Marine invertebrates are promising sources of novel bioactive secondary metabolites, and organisms like sponges, ascidians and nudibranchs are characterised by possessing potent defensive chemicals.
Justin M. McNab, Jorge Rodríguez, Peter Karuso, Jane E. Williamson   +3 more
doaj   +1 more source

Tetrodotoxin for Chemotherapy-Induced Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Dose Finding Trial

Toxins, 2021
Tetrodotoxin (TTX) has emerged as a potentially efficacious agent for chemotherapy-induced neuropathic pain (CINP), a prevalent, debilitating condition often resistant to analgesics.
Samuel A. Goldlust, Mojgan Kavoosi, Jennifer Nezzer, Mehran Kavoosi, Walter Korz, Kenneth Deck   +5 more
doaj   +1 more source

Primary Structure and Conformation of a Tetrodotoxin-Binding Protein in the Hemolymph of Non-Toxic Shore Crab Hemigrapsus sanguineus

Journal of Marine Science and Engineering, 2023
Tetrodotoxin (TTX)-binding proteins are present in toxic TTX-bearing animals, such as pufferfish and gastropods. These may prevent autotoxicity. However, TTX-binding proteins are also found in the nontoxic marine shore crab, Hemigrapsus sanguineus. Here,
Yuji Nagashima, Kenta Fujimoto, Masahiko Okai, Yoichiro Kitani, Aya Yoshinaga-Kiriake, Shoichiro Ishizaki   +5 more
doaj   +1 more source

Tetrodotoxins Secretion and Voltage-Gated Sodium Channel Adaptation in the Ribbon Worm Kulikovia alborostrata (Takakura, 1898) (Nemertea)

Toxins, 2021
Nemertea is a phylum of marine worms whose members bear various toxins, including tetrodotoxin (TTX) and its analogues. Despite the more than 30 years of studying TTXs in nemerteans, many questions regarding their functions and the mechanisms ensuring ...
Anna E. Vlasenko, Vasiliy G. Kuznetsov, Grigorii V. Malykin, Alexandra O. Pereverzeva, Peter V. Velansky, Konstantin V. Yakovlev, Timur Yu. Magarlamov   +6 more
doaj   +1 more source

Intrabody Tetrodotoxin Distribution and Possible Hypothesis for Its Migration in Ribbon Worms Cephalothrix cf. simula (Palaeonemertea, Nemertea)

Marine Drugs, 2021
Tetrodotoxin (TTX) is a potent neurotoxin found in many marine and terrestrial animals, but only a few species, such as the ribbon worms of the genus Cephalothrix, accumulate it in extremely high concentrations.
Grigorii V. Malykin, Alexei V. Chernyshev, Timur Yu. Magarlamov   +2 more
doaj   +1 more source

Case of Paraesthesia Developed After Consuming Pufferfish

Türk Yoğun Bakim Derneği Dergisi, 2021
Pufferfish, also known globally as ballfish, globefish and toadfish, is a fish species belonging to the Tetrodontiformes family. Following the consumption of this fish, tetrodotoxin (TTX), a type of neurotoxin, causes a rare type of intoxication.
Mehmet Murat Çelik, Levent Özdemir, Nazlı Deniz Ateş, Resul Akyol, Hakan Karabay, Adem Çiftci, Ömer Faruk Çelik   +6 more
doaj   +1 more source