Accumulation of Dense Core Vesicles in Hippocampal Synapses Following Chronic Inactivity [PDF]
Frontiers in Neuroanatomy, 2018 The morphology and function of neuronal synapses are regulated by neural activity, as manifested in activity-dependent synapse maturation and various forms of synaptic plasticity.
Chang-Lu Tao +16 more
doaj +4 more sources
Investigating Diet as the Source of Tetrodotoxin in Pleurobranchaea maculata [PDF]
Marine Drugs, 2013 The origin of tetrodotoxin (TTX) is highly debated; researchers have postulated either an endogenous or exogenous source with the host accumulating TTX symbiotically or via food chain transmission.
Serena Khor +6 more
doaj +3 more sources
Risks for public health related to the presence of tetrodotoxin (TTX) and TTX analogues in marine bivalves and gastropods [PDF]
EFSA Journal, 2017 Tetrodotoxin (TTX) and its analogues are produced by marine bacteria and have been detected in marine bivalves and gastropods from European waters. The European Commission asked EFSA for a scientific opinion on the risks to public health related to the ...
EFSA Panel on Contaminants in the Food Chain (CONTAM) +30 more
doaj +2 more sources
Intracellular Immunohistochemical Detection of Tetrodotoxin in Pleurobranchaea maculata (Gastropoda) and Stylochoplana sp. (Turbellaria) [PDF]
Marine Drugs, 2015 Tetrodotoxin (TTX), is a potent neurotoxin targeting sodium channels that has been identified in multiple marine and terrestrial organisms. It was recently detected in the Opisthobranch Pleurobranchaea maculata and a Platyhelminthes Stylochoplana sp ...
Lauren R. Salvitti +3 more
doaj +4 more sources
Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection
Toxins, 2014 Tetrodotoxin (TTX) is a naturally occurring toxin that has been responsible for human intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated puffer fish which are a culinary delicacy, especially in Japan.
Mary Lehane +2 more
exaly +3 more sources
Nanozyme-Based Colorimetric Assay on a Magnetic Microfluidic Platform for Integrated Detection of TTX [PDF]
BiosensorsTetrodotoxin (TTX) is a potent marine neurotoxin, necessitating sensitive and user-friendly on-site assays. To address long workflows of traditional immunoassays and limited signal amplification in colorimetric microfluidics, we developed a nanozyme ...
Chenqi Zhang +6 more
doaj +2 more sources
Chemical properties and biological activities of three highly purified major tetrodotoxin analogues [PDF]
Proceedings of the Japan Academy. Series B, Physical and Biological SciencesTetrodotoxin (TTX), the pufferfish toxin, has the potential to cause fatal food poisoning because of its potent voltage-gated sodium channel (Nav) blocking activity.
Mari YOTSU-YAMASHITA +7 more
doaj +2 more sources
Current Biology, 2016 In this Quick Guide, Lorentz et al. discuss the function of tetrodotoxin and its distribution in the animal kingdom.
Max N, Lorentz +3 more
openaire +3 more sources
Marine Drugs, 2021 The von Willebrand factor type D (VWD) domain in vitellogenin has recently been found to bind tetrodotoxin. The way in which this protein domain associates with tetrodotoxin and participates in transporting tetrodotoxin in vivo remains unclear.
Kun Qiao +11 more
doaj +1 more source
Reversible cerebral vasoconstriction syndrome associated with tetrodotoxin poisoning: A case report
Journal of the American College of Emergency Physicians Open, 2021 An 81‐year‐old woman with a history of hypertension and Alzheimer's disease presented to the emergency department because of impaired consciousness. Physical examination revealed acute progressive generalized flaccid paralysis, hypertension, respiratory ...
Eiichi Kakehi +10 more
doaj +1 more source