Results 21 to 30 of about 11,247 (202)

No evidence for a culturable bacterial tetrodotoxin producer in Pleurobranchaea maculata (Gastropoda: Pleurobranchidae) and Stylochoplana sp. (Platyhelminthes: Polycladida) [PDF]

, 2015
Tetrodotoxin (TTX) is a potent neurotoxin found in the tissues of many taxonomically diverse organisms. Its origin has been the topic of much debate, with suggestions including endogenous production, acquisition through diet, and symbiotic bacterial ...
Salvitti, Lauren R., Susanna A. Wood, Paul McNabb, Lauren Salvitti, McNabb, Paul, Cary, S. Craig, Susanna Wood, Wood, Susanna A., Stephen Cary, Lauren R. Salvitti, Stephen Craig Cary   +10 more
core   +1 more source

The Structural Basis and Functional Consequences of Interactions Between Tetrodotoxin and Voltage-Gated Sodium Channels

Marine Drugs, 2006
: Tetrodotoxin (TTX) is a highly specific blocker of voltage-gated sodium channels. The dissociation constant of block varies with different channel isoforms.
C. Ruben, Shana L. Geffeney
doaj   +1 more source

Diversity and Biosynthetic Potential of Culturable Microbes Associated with Toxic Marine Animals [PDF]

, 2013
Tetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported.
Kalaitzis, John, Brett A. Neilan, Susanna A. Wood, Neilan, Brett, John Kalaitzis, Susanna Wood, Brett Neilan, Chau, Rocky, Rocky Chau, Wood, Susanna A., John A. Kalaitzis   +10 more
core   +1 more source

Total Synthesis of Tetrodotoxin

, 2022
Total Synthesis of ...
Qi Xiangbing (10913622)
core   +1 more source

Stereocontrolled Total Synthesis of Tetrodotoxin from -Inositol and D-Glucose by Three Routes: Aspects for Constructing Complex Multi-Functionalized Cyclitols with Branched-Chain Structures

Natural Product Communications, 2015
This report describes the stereocontrolled total synthesis of the multi-functionalized cyclitol derivative, tetrodotoxin, containing eight asymmetric carbons and different types of branched-chains, from myo -inositol and D-glucose using three different ...
Ken-Ichi Sato, Shoji Akai, Juji Yoshimura   +2 more
doaj   +1 more source

Association between Tetrodotoxin Resistant Channels and Lipid Rafts Regulates Sensory Neuron Excitability [PDF]

, 2012
PubMed ID: 22870192This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Baker, MD, Alessandro Pristerà (146521), Kenji Okuse (146542), Pristera, A, Mark D Baker, Mark D. Baker (146531), Okuse, K, Kenji Okuse, Alessandro Pristerà   +8 more
core   +2 more sources

Total Synthesis of Tetrodotoxin [PDF]

, 2020
A total synthesis of tetrodotoxin was accomplished. A Diels–Alder reaction between a known enone and a siloxy diene gave a tricyclic product, the steric bias of which was used to construct the remaining stereogenic centers. A nitrogen atom was introduced
Satoshi Yokoshima, Murakami, Keigo, Fukuyama, Tohru, Keigo Murakami, Toma, Tatsuya, Tohru Fukuyama, Yokoshima, Satoshi, Tatsuya Toma   +7 more
core   +1 more source

Isolation, Identification, and Characterization of Tetrodotoxin Producing Bacillus amyloliquefaciens B1 Originated from Carcinoscorpius rotundicauda [PDF]

, 2023
This study isolated and identified Bacillus amyloliquefaciens B1 from Carcinoscorpius rotundicauda by carrying out the 16S rRNA sequence analysis, reconstructing the phylogenetic tree based on the Environment for Tree Exploration (ETE3) v3.1.1 belonging ...
Tu Ho, Canh Le, Phong Le, Yen Tran, Tu Nguyen, Phuc Hua, Tra Doan, Bao Phan   +7 more
core   +1 more source

Stereocontrolled Total Synthesis of Tetrodotoxin from Inositol and D-Glucose by Three Routes: Aspects for Constructing Complex Multi-Functionalized Cyclitols with Branched-Chain Structures

Natural Product Communications, 2013
This report describes the stereocontrolled total synthesis of the multi-functionalized cyclitol derivative tetrodotoxin containing eight asymmetric carbons and different types of branched-chains from myo -inositol and D-glucose using three different ...
Ken-ichi Sato, Shoji Akai, Juji Yoshimura   +2 more
doaj   +1 more source

Hepatorenal Toxicity after 7-Day Oral Administration of Low-Dose Tetrodotoxin and Its Distribution in the Main Tissues in Mice

Toxins, 2023
Tetrodotoxin (TTX) is a highly toxic compound detected in various edible marine animals even in European waters. To characterize the hazard by oral exposure to TTX, its tissue distribution was evaluated after single (75 μg/kg) or 7-day (25–125 μg/kg ...
Yaqian Zhong, Xiaojun Zhang, Qiyu Yang, Qianfeng Wang   +3 more
doaj   +1 more source