Results 1 to 10 of about 29,634 (242)

Tetrodotoxin (TTX) as a Therapeutic Agent for Pain [PDF]

open access: yesMarine Drugs, 2012
Tetrodotoxin (TTX) is a potent neurotoxin that blocks voltage-gated sodium channels (VGSCs). VGSCs play a critical role in neuronal function under both physiological and pathological conditions.
FRANCISCO R Nieto   +2 more
exaly   +8 more sources

The Chemical and Evolutionary Ecology of Tetrodotoxin (TTX) Toxicity in Terrestrial Vertebrates

open access: yesMarine Drugs, 2010
Tetrodotoxin (TTX) is widely distributed in marine taxa, however in terrestrial taxa it is limited to a single class of vertebrates (Amphibia). Tetrodotoxin present in the skin and eggs of TTX-bearing amphibians primarily serves as an antipredator ...
Charles T Hanifin, Hanifin Charles T
exaly   +4 more sources

Identifying environmental factors associated with tetrodotoxin contamination in bivalve mollusks using eXplainable AI [PDF]

open access: yesnpj Science of Food
Since 2012, tetrodotoxin (TTX) has been found in seafoods such as bivalve mollusks in temperate European waters. TTX contamination leads to food safety risks and economic losses, making early prediction of TTX contamination vital to the food industry and
M. C. Schoppema   +6 more
doaj   +2 more sources

The impact of tetrodotoxin (TTX) on the gut microbiome in juvenile tiger pufferfish, Takifugu rubripes

open access: yesScientific Reports
Tetrodotoxin (TTX) is a potent neurotoxin that accumulates in Takifugu rubripes, commonly known as pufferfish, through the ingestion of TTX-bearing organisms as part of their food chain.
Koji Hamasaki   +2 more
exaly   +2 more sources

A Progress on the Application of Tetrodotoxin [PDF]

open access: yesE3S Web of Conferences, 2021
Tetrodotoxin (TTX), a blocker of sodium channels, exists in the pufferfish, amphibians, and octopus, and originated in endosymbiont-vibrio. Researches have confirmed that TTX affected the action potential through the regulation of voltage-gated sodium ...
Wang Zhaojia, Zhou Zhenning
doaj   +1 more source

ttX calculations and modeling [PDF]

open access: yesProceedings of The Ninth Annual Conference on Large Hadron Collider Physics — PoS(LHCP2021), 2021
In this talk, we review the status of calculations for the associated production of a top pair and a Higgs, $W$ or $Z$ boson at the Large Hadron Collider. In particular, we focus on the resummation of soft gluon emission effects and on their combination with the complete set of next-to-leading-order corrections of both QCD and electroweak origin, in ...
Ferroglia, Andrea   +5 more
openaire   +1 more source

Acute Toxic Effects of Tetrodotoxin in Mice via Intramuscular Injection and Oral Gavage

open access: yesToxins, 2023
Tetrodotoxin (TTX) is a highly fatal marine biotoxin. Constantly increasing intoxications and the lack of specific antitoxic drugs in clinical applications highlight the need for further research into the toxic effects of TTX.
Fan Wang   +7 more
doaj   +1 more source

Local Differences in the Toxin Amount and Composition of Tetrodotoxin and Related Compounds in Pufferfish (Chelonodon patoca) and Toxic Goby (Yongeichthys criniger) Juveniles

open access: yesToxins, 2022
Tetrodotoxin (TTX)-bearing fish ingest TTX from their preys through the food chain and accumulate TTX in their bodies. Although a wide variety of TTX-bearing organisms have been reported, the missing link in the TTX supply chain has not been elucidated ...
Masaaki Ito   +12 more
doaj   +1 more source

In Silico Analysis of Tetrodotoxin Binding in Voltage-Gated Sodium Ion Channels from Toxin-Resistant Animal Lineages

open access: yesMarine Drugs, 2022
Multiple animal species have evolved resistance to the neurotoxin tetrodotoxin (TTX) through changes in voltage-gated sodium ion channels (VGSCs). Amino acid substitutions in TTX-resistant lineages appear to be positionally convergent with changes in ...
Shana L. Geffeney   +3 more
doaj   +1 more source

An Overview of the Anatomical Distribution of Tetrodotoxin in Animals

open access: yesToxins, 2022
Tetrodotoxin (TTX), a potent paralytic sodium channel blocker, is an intriguing marine toxin. Widely distributed in nature, TTX has attracted attention in various scientific fields, from biomedical studies to environmental safety concerns. Despite a long
Daria I. Melnikova, Timur Yu. Magarlamov
doaj   +1 more source

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