Results 1 to 10 of about 56,272 (223)
Investigating Diet as the Source of Tetrodotoxin in Pleurobranchaea maculata [PDF]
Marine Drugs, 2013 The origin of tetrodotoxin (TTX) is highly debated; researchers have postulated either an endogenous or exogenous source with the host accumulating TTX symbiotically or via food chain transmission.
Serena Khor +6 more
doaj +3 more sources
The Chemical and Evolutionary Ecology of Tetrodotoxin (TTX) Toxicity in Terrestrial Vertebrates
Marine Drugs, 2010 Tetrodotoxin (TTX) is widely distributed in marine taxa, however in terrestrial taxa it is limited to a single class of vertebrates (Amphibia). Tetrodotoxin present in the skin and eggs of TTX-bearing amphibians primarily serves as an antipredator ...
Charles T Hanifin
exaly +3 more sources
Diversity and Biosynthetic Potential of Culturable Microbes Associated with Toxic Marine Animals [PDF]
Marine Drugs, 2013 Tetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported.
Brett A. Neilan +3 more
doaj +4 more sources
Tetrodotoxin (TTX) as a Therapeutic Agent for Pain
Marine Drugs, 2012 Tetrodotoxin (TTX) is a potent neurotoxin that blocks voltage-gated sodium channels (VGSCs). VGSCs play a critical role in neuronal function under both physiological and pathological conditions.
Francisco R Nieto, Enrique José Cobos
exaly +3 more sources
Intracellular Immunohistochemical Detection of Tetrodotoxin in Pleurobranchaea maculata (Gastropoda) and Stylochoplana sp. (Turbellaria) [PDF]
Marine Drugs, 2015 Tetrodotoxin (TTX), is a potent neurotoxin targeting sodium channels that has been identified in multiple marine and terrestrial organisms. It was recently detected in the Opisthobranch Pleurobranchaea maculata and a Platyhelminthes Stylochoplana sp ...
Lauren R. Salvitti +3 more
doaj +4 more sources
A Progress on the Application of Tetrodotoxin [PDF]
E3S Web of Conferences, 2021 Tetrodotoxin (TTX), a blocker of sodium channels, exists in the pufferfish, amphibians, and octopus, and originated in endosymbiont-vibrio. Researches have confirmed that TTX affected the action potential through the regulation of voltage-gated sodium ...
Wang Zhaojia, Zhou Zhenning
doaj +1 more source
ttX calculations and modeling [PDF]
Proceedings of The Ninth Annual Conference on Large Hadron Collider Physics — PoS(LHCP2021), 2021 In this talk, we review the status of calculations for the associated production of a top pair and a Higgs, $W$ or $Z$ boson at the Large Hadron Collider. In particular, we focus on the resummation of soft gluon emission effects and on their combination with the complete set of next-to-leading-order corrections of both QCD and electroweak origin, in ...
Andrea Ferroglia +5 more
openaire +1 more source
Acute Toxic Effects of Tetrodotoxin in Mice via Intramuscular Injection and Oral Gavage
Toxins, 2023 Tetrodotoxin (TTX) is a highly fatal marine biotoxin. Constantly increasing intoxications and the lack of specific antitoxic drugs in clinical applications highlight the need for further research into the toxic effects of TTX.
Fan Wang +7 more
doaj +1 more source
Toxins, 2022 Tetrodotoxin (TTX)-bearing fish ingest TTX from their preys through the food chain and accumulate TTX in their bodies. Although a wide variety of TTX-bearing organisms have been reported, the missing link in the TTX supply chain has not been elucidated ...
Masaaki Ito +12 more
doaj +1 more source
Marine Drugs, 2022 Multiple animal species have evolved resistance to the neurotoxin tetrodotoxin (TTX) through changes in voltage-gated sodium ion channels (VGSCs). Amino acid substitutions in TTX-resistant lineages appear to be positionally convergent with changes in ...
Shana L. Geffeney +3 more
doaj +1 more source