Results 41 to 50 of about 56,272 (223)

Functionalization of synthetic talc-like phyllosilicates by alkoxyorganosilane grafting [PDF]

, 2010
A range of talc-like phyllosilicates were prepared via a hydrothermal synthesis performed at five different temperatures from 160 to 350 °C. The organization of the lattice and the degree of crystallinity of the new materials were evaluated by different ...
Bonino, Jean-Pierre, Brendlé, Jocelyne, Gressier, Marie, Joncoux-Chabrol, Karine, Marichal, Claire, Martin, François, Menu, Marie-Joëlle, Pébère, Nadine   +7 more
core   +2 more sources

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Effect of Tetrodotoxin Pellets in a Rat Model of Postherpetic Neuralgia

Marine Drugs, 2018
Postherpetic neuralgia (PHN) is nerve pain caused by a reactivation of the varicella zoster virus. Medications are used to reduce PHN but their use is limited by serious side effects.
Bihong Hong, Jipeng Sun, Hongzhi Zheng, Qingqing Le, Changsen Wang, Kaikai Bai, Jianlin He, Huanghuang He, Yanming Dong   +8 more
doaj   +1 more source

Changes in tetrodotoxin-resistant C-fibre activity during fatiguing isometric contractions in the rat. [PDF]

PLoS ONE, 2013
It is by now well established that tetrodotoxin-resistant (TTX-R) afferent fibres from muscle in the rat exhibit a multisensitive profile, including nociception.
Ivana Kalezic, Heinz Steffens
doaj   +1 more source

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]

, 2007
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma, Kennedy, Charles, Tasker, Paul N., Westfall, Timothy D.   +3 more
core   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Seasonal Changes in the Tetrodotoxin Content of the Flatworm Planocera multitentaculata

Marine Drugs, 2017
Tetrodotoxin (TTX) is a potent neurotoxin that acts specifically on voltage-gated sodium channels on excitable membranes of muscle and nerve tissues. The biosynthetic process for TTX is unclear, although marine bacteria are generally thought to be the ...
Riko Yamada, Tadasuke Tsunashima, Mitsuki Takei, Tatsunori Sato, Yoshiki Wajima, Makoto Kawase, Shotaro Oshikiri, Yusuke Kajitani, Keita Kosoba, Hiroyuki Ueda, Koko Abe, Shiro Itoi, Haruo Sugita   +12 more
doaj   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

Toxic mechanism and detection methods of tetrodotoxin [PDF]

MATEC Web of Conferences
Tetrodotoxin (TTX) was first isolated in the early 20th century and has significant public health implications, especially in areas where puffer fish are consumed, such as Japan.
Xu Yunzhe
doaj   +1 more source

Hepatorenal Toxicity after 7-Day Oral Administration of Low-Dose Tetrodotoxin and Its Distribution in the Main Tissues in Mice

Toxins, 2023
Tetrodotoxin (TTX) is a highly toxic compound detected in various edible marine animals even in European waters. To characterize the hazard by oral exposure to TTX, its tissue distribution was evaluated after single (75 μg/kg) or 7-day (25–125 μg/kg ...
Yaqian Zhong, Xiaojun Zhang, Qiyu Yang, Qianfeng Wang   +3 more
doaj   +1 more source