Results 21 to 30 of about 25,336 (202)

Distribution of Tetrodotoxin in Pacific Oysters (Crassostrea gigas)

Marine Drugs, 2021
A potent and heat-stable tetrodotoxin (TTX) has been found to accumulate in various marine bivalve species, including Pacific oysters (Crassostrea gigas), raising a food safety concern.
Monika Dhanji-Rapkova, Andrew D. Turner, Craig Baker-Austin, Jim F. Huggett, Jennifer M. Ritchie   +4 more
doaj   +1 more source

The skin microbiome facilitates adaptive tetrodotoxin production in poisonous newts

eLife, 2020
Rough-skinned newts (Taricha granulosa) use tetrodotoxin (TTX) to block voltage-gated sodium (Nav) channels as a chemical defense against predation.
Patric M Vaelli, Kevin R Theis, Janet E Williams, Lauren A O'Connell, James A Foster, Heather L Eisthen   +5 more
doaj   +1 more source

Contribution of tetrodotoxin-resistant persistent Na+ currents to the excitability of C-type dural afferent neurons in rats

The Journal of Headache and Pain, 2022
Background Growing evidence supports the important role of persistent sodium currents (INaP) in the neuronal excitability of various central neurons.
Michiko Nakamura, Il-Sung Jang
doaj   +1 more source

La serpiente y el arco iris (1988): un modelo fisiopatológico por sobredosis de tetrodotoxina

Revista de Medicina y Cine / Journal of Medicine and Movies
La Serpiente y el Arco Iris (1988) de Wes Craven supone un modelo docente atractivo que combina la farmacología y las alteraciones fisiológicas en muchos sistemas funcionales. Basada en un hecho real, este clásico del terror convertido en una película de
Carmen Fernández-Martos, Nora Suleiman-Martos, José Luis Gómez-Urquiza, Isabel Prieto-Gómez, Manuel Ramírez-Sánchez, Ana Belén Segarra-Robles, Francisco García-Cózar, Germán Domínguez-Vías   +7 more
doaj   +1 more source

Differing alterations of sodium currents in small dorsal root ganglion neurons after ganglion compression and peripheral nerve injury

Molecular Pain, 2008
Voltage-gated sodium channels play important roles in modulating dorsal root ganglion (DRG) neuron hyperexcitability and hyperalgesia after peripheral nerve injury or inflammation.
Song Xue-Jun, Huang Zhi-Jiang
doaj   +1 more source

Investigating Diet as the Source of Tetrodotoxin in Pleurobranchaea maculata

Marine Drugs, 2013
The origin of tetrodotoxin (TTX) is highly debated; researchers have postulated either an endogenous or exogenous source with the host accumulating TTX symbiotically or via food chain transmission.
Serena Khor, Susanna A. Wood, Lauren Salvitti, David I. Taylor, Janet Adamson, Paul McNabb, Stephen Craig Cary   +6 more
doaj   +1 more source

Tetrodotoxins Secretion and Voltage-Gated Sodium Channel Adaptation in the Ribbon Worm Kulikovia alborostrata (Takakura, 1898) (Nemertea)

Toxins, 2021
Nemertea is a phylum of marine worms whose members bear various toxins, including tetrodotoxin (TTX) and its analogues. Despite the more than 30 years of studying TTXs in nemerteans, many questions regarding their functions and the mechanisms ensuring ...
Anna E. Vlasenko, Vasiliy G. Kuznetsov, Grigorii V. Malykin, Alexandra O. Pereverzeva, Peter V. Velansky, Konstantin V. Yakovlev, Timur Yu. Magarlamov   +6 more
doaj   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

Effect of Tetrodotoxin Pellets in a Rat Model of Postherpetic Neuralgia

Marine Drugs, 2018
Postherpetic neuralgia (PHN) is nerve pain caused by a reactivation of the varicella zoster virus. Medications are used to reduce PHN but their use is limited by serious side effects.
Bihong Hong, Jipeng Sun, Hongzhi Zheng, Qingqing Le, Changsen Wang, Kaikai Bai, Jianlin He, Huanghuang He, Yanming Dong   +8 more
doaj   +1 more source

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source