Results 31 to 40 of about 56,272 (223)

Distribution of Tetrodotoxin in Pacific Oysters (Crassostrea gigas)

open access: yesMarine Drugs, 2021
A potent and heat-stable tetrodotoxin (TTX) has been found to accumulate in various marine bivalve species, including Pacific oysters (Crassostrea gigas), raising a food safety concern.
Monika Dhanji-Rapkova   +4 more
doaj   +1 more source

Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. [PDF]

open access: yes, 2015
Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to
Ch'ng, Toh Hean   +5 more
core   +1 more source

The skin microbiome facilitates adaptive tetrodotoxin production in poisonous newts

open access: yeseLife, 2020
Rough-skinned newts (Taricha granulosa) use tetrodotoxin (TTX) to block voltage-gated sodium (Nav) channels as a chemical defense against predation.
Patric M Vaelli   +5 more
doaj   +1 more source

Contribution of tetrodotoxin-resistant persistent Na+ currents to the excitability of C-type dural afferent neurons in rats

open access: yesThe Journal of Headache and Pain, 2022
Background Growing evidence supports the important role of persistent sodium currents (INaP) in the neuronal excitability of various central neurons.
Michiko Nakamura, Il-Sung Jang
doaj   +1 more source

A sensorimotor area (NIf) is required for the production of learned vocalizations [PDF]

open access: yes, 2011
Sensory feedback is essential for the acquisition of complex motor behaviors, including birdsong. In zebra finches, auditory feedback is relayed to the descending motor pathway primarily through the nucleus interfacialis nidopalii (NIf).
Bence P. Ö, Sharon M. H. Gobes
core   +2 more sources

Na(V)1.5 sodium channel window currents contribute to spontaneous firing in olfactory sensory neurons [PDF]

open access: yes, 2014
Olfactory sensory neurons (OSNs) fire spontaneously as well as in response to odor; both forms of firing are physiologically important. We studied voltage-gated Na+ channels in OSNs to assess their role in spontaneous activity.
Dionne, Vincent E.   +6 more
core   +1 more source

La serpiente y el arco iris (1988): un modelo fisiopatológico por sobredosis de tetrodotoxina

open access: yesRevista de Medicina y Cine / Journal of Medicine and Movies
La Serpiente y el Arco Iris (1988) de Wes Craven supone un modelo docente atractivo que combina la farmacología y las alteraciones fisiológicas en muchos sistemas funcionales. Basada en un hecho real, este clásico del terror convertido en una película de
Carmen Fernández-Martos   +7 more
doaj   +1 more source

Effects of cromakalim (BRL 34915) on potassium conductances in CA3 neurons of the guinea-pig hippocampus in vitro [PDF]

open access: yes, 1989
The action of the potassium channel activator, cromakalim (BRL 34915), on membrane potential, input resistance and current-voltage-relationship of CA3 neurons in a slice preparation of the guinea-pig hippocampus was investigated by means of intracellular
Alzheimer, Christian   +2 more
core   +1 more source

Differing alterations of sodium currents in small dorsal root ganglion neurons after ganglion compression and peripheral nerve injury

open access: yesMolecular Pain, 2008
Voltage-gated sodium channels play important roles in modulating dorsal root ganglion (DRG) neuron hyperexcitability and hyperalgesia after peripheral nerve injury or inflammation.
Song Xue-Jun, Huang Zhi-Jiang
doaj   +1 more source

Tetrodotoxins Secretion and Voltage-Gated Sodium Channel Adaptation in the Ribbon Worm Kulikovia alborostrata (Takakura, 1898) (Nemertea)

open access: yesToxins, 2021
Nemertea is a phylum of marine worms whose members bear various toxins, including tetrodotoxin (TTX) and its analogues. Despite the more than 30 years of studying TTXs in nemerteans, many questions regarding their functions and the mechanisms ensuring ...
Anna E. Vlasenko   +6 more
doaj   +1 more source

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