Results 11 to 20 of about 11,247 (202)

Tetrodotoxin Concentrations in Pleurobranchaea maculata: Temporal, Spatial and Individual Variability from New Zealand Populations [PDF]

Marine Drugs, 2012
Tetrodotoxin (TTX) is a potent neurotoxin that has been identified in a range of phylogenetically unrelated marine and terrestrial organisms. Tetrodotoxin was recently detected in New Zealand in Pleurobranchaea maculata (the grey side-gilled sea slug ...
Stephen Craig Cary, Susanna A. Wood, Janet Adamson, Paul McNabb, Jarrod Walker, David I. Taylor   +5 more
doaj   +2 more sources

Total syntheses of Tetrodotoxin and 9-epiTetrodotoxin

Nature Communications
Tetrodotoxin and congeners are specific voltage-gated sodium channel blockers that exhibit remarkable anesthetic and analgesic effects. Here, we present a scalable asymmetric syntheses of Tetrodotoxin and 9-epiTetrodotoxin from the abundant chemical ...
Peihao Chen, Jing Wang, Shuangfeng Zhang, Yan Wang, Yuze Sun, Songlin Bai, Qingcui Wu, Xinyu Cheng, Peng Cao, Xiangbing Qi   +9 more
doaj   +2 more sources

Total Synthesis of Tetrodotoxin and 9-epiTetrodotoxin [PDF]

, 2023
Tetrodotoxin and congeners are specific voltage-gated sodium channel blockers that exhibit remarkable anesthetic and an-algesic effects. Here, we present a scalable asymmetric synthesis of TTX and 9-epiTTX from the abundant chemical feed-stock furfuryl ...
Yuze, Sun, Qingcui, Wu, Xinyu, Cheng, Peihao, chen, Songlin , Bai, Yan, Wang, Xiangbing, Qi, Peng, Cao, Shuangfeng, Zhang, Jing, Wang   +9 more
core   +2 more sources

An Overview of the Anatomical Distribution of Tetrodotoxin in Animals

Toxins, 2022
Tetrodotoxin (TTX), a potent paralytic sodium channel blocker, is an intriguing marine toxin. Widely distributed in nature, TTX has attracted attention in various scientific fields, from biomedical studies to environmental safety concerns. Despite a long
Daria I. Melnikova, Timur Yu. Magarlamov
doaj   +1 more source

Multi-Omics Analysis of Gene and Protein Candidates Possibly Related to Tetrodotoxin Accumulation in the Skin of Takifugu flavidus

Marine Drugs, 2021
Pufferfish is increasingly regarded by many as a delicacy. However, the tetrodotoxin (TTX) that accumulates in its body can be lethal upon consumption by humans.
Huimin Feng, Kun Qiao, Chunchun Wang, Bei Chen, Min Xu, Hua Hao, Zhen Huang, Zhiyu Liu, Qin Wang   +8 more
doaj   +1 more source

Intracellular immunohistochemical detection of tetrodotoxin in Pleurobranchaea maculata (Gastropoda) and Stylochoplana sp. (Turbellaria) [PDF]

, 2015
Tetrodotoxin (TTX), is a potent neurotoxin targeting sodium channels that has been identified in multiple marine and terrestrial organisms. It was recently detected in the Opisthobranch Pleurobranchaea maculata and a Platyhelminthes Stylochoplana sp ...
Cary, Stephen Craig, Salvitti, Lauren R., Susanna A. Wood, Lauren Salvitti, Winsor, Leigh, Cary, S. Craig, Susanna Wood, Wood, Susanna A., Leigh Winsor, Stephen Cary, Lauren R. Salvitti, Stephen Craig Cary   +11 more
core   +1 more source

Tetrodotoxin and the Geographic Distribution of the Blue-Lined Octopus Hapalochlaena fasciata on the Korean Coast

Toxins, 2023
The genus Hapalochlaena, including the blue-lined octopus Hapalochlaena fasciata (H. fasciata), is highly toxic. Venomous, blue-lined octopuses were recently found in Korea, but their toxicity, toxin composition, and distribution remain largely unknown ...
Ji-Hoe Kim, Dong-Wook Kim, Sung-Rae Cho, Ka-Jeong Lee, Jong-Soo Mok   +4 more
doaj   +1 more source

Structural Characterization and Spatial Mapping of Tetrodotoxins in Australian Polyclads

Marine Drugs, 2022
Tetrodotoxin (TTX) is a potent marine neurotoxin that occurs in several Australian phyla, including pufferfish, toadfish, gobies, and the blue-ringed octopus.
Justin M. McNab, Matthew T. Briggs, Jane E. Williamson, Peter Hoffmann, Jorge Rodriguez, Peter Karuso   +5 more
doaj   +1 more source

Investigating diet as the source of tetrodotoxin in Pleurobranchaea maculata [PDF]

, 2014
The origin of tetrodotoxin (TTX) is highly debated; researchers have postulated either an endogenous or exogenous source with the host accumulating TTX symbiotically or via food chain transmission.
Salvitti, Lauren R., Adamson, Janet E., McNabb, Paul, Cary, S. Craig, Khor, Serena, Wood, Susanna A., Taylor, David I.   +6 more
core   +1 more source

Development of a Proton-Enhanced ESI UPLC-MS/MS Method for the Determination of Tetrodotoxin

Molecules, 2022
Tetrodotoxin (TTX) is a kind of low-molecular-weight non-protein neurotoxin. It is one of the most potent neurotoxins found in nature, and it is found in puffer fish and various marine biota.
Tong Li, Ruiguo Wang, Peilong Wang
doaj   +1 more source