First Report of Two Gymnodimines and Two Tetrodotoxin Analogues in Invertebrates from the North Atlantic Coast of Spain [PDF]
Marine Drugs, 2023 Gymnodimine D (GYM D), 16-desmethyl gymnodimine D (16-desmethyl GYM D), and two tetrodotoxin analogues have been found in invertebrates obtained from the north Atlantic coast of Spain from May 2021 to October 2022.
Araceli E. Rossignoli +3 more
doaj +4 more sources
Evaluation of Toxicity Equivalency Factors of Tetrodotoxin Analogues with a Neuro-2a Cell-Based Assay and Application to Puffer Fish from Greece [PDF]
Marine Drugs, 2023 Tetrodotoxin (TTX) is a potent marine neurotoxin involved in poisoning cases, especially through the consumption of puffer fish. Knowledge of the toxicity equivalency factors (TEFs) of TTX analogues is crucial in monitoring programs to estimate the ...
Mounira Alkassar +9 more
doaj +5 more sources
Chemical properties and biological activities of three highly purified major tetrodotoxin analogues [PDF]
Proceedings of the Japan Academy. Series B, Physical and Biological SciencesTetrodotoxin (TTX), the pufferfish toxin, has the potential to cause fatal food poisoning because of its potent voltage-gated sodium channel (Nav) blocking activity.
Mari YOTSU-YAMASHITA +7 more
doaj +5 more sources
Lack of tetrodotoxin analogues and individual metabolomic profiling of the cryptic frog Colostethus imbricolus. [PDF]
PLoS ONEPoison frogs (Dendrobatoidea) are characterized by the great diversity of alkaloids discovered in their skin. However, most of these alkaloids have been found in brightly colored species and there is a wide lack of knowledge of alkaloid profiles in the ...
Mabel Gonzalez +2 more
doaj +3 more sources
Selective Blocking Effects of 4,9-Anhydrotetrodotoxin, Purified from a Crude Mixture of Tetrodotoxin Analogues, on NaV1.6 Channels and Its Chemical Aspects [PDF]
Marine Drugs, 2015 Tetrodotoxin (TTX) is a potent neurotoxin found in a number of marine creatures including the pufferfish, where it is synthesized by bacteria and accumulated through the food chain.
Mari Yotsu-Yamashita +2 more
exaly +4 more sources
Tetrodotoxin and Its Analogues (TTXs) in the Food-Capture and Defense Organs of the Palaeonemertean Cephalothrix cf. simula [PDF]
ToxinsTetrodotoxin (TTX), an extremely potent low-molecular-weight neurotoxin, is widespread among marine animals including ribbon worms (Nemertea). Previously, studies on the highly toxic palaeonemertean Cephalothrix cf.
Grigorii V. Malykin +2 more
doaj +4 more sources
Public Health Risks Associated with Tetrodotoxin and Its Analogues in European Waters: Recent Advances after The EFSA Scientific Opinion [PDF]
Toxins, 2019 Tetrodotoxin (TTX) and its analogues are naturally occurring toxins responsible worldwide for human intoxication cases and fatalities, mainly associated with pufferfish consumption. In the last decade, TTXs were detected in marine bivalves and gastropods
Panagiota Katikou
exaly +5 more sources
Pufferfish Saxitoxin and Tetrodotoxin Binding Protein (PSTBP) Analogues in the Blood Plasma of the Pufferfish Arothron nigropunctatus, A. hispidus, A. manilensis, and Chelonodon patoca [PDF]
Marine Drugs, 2018 Pufferfish saxitoxin and tetrodotoxin (TTX) binding protein (PSTBP) is a glycoprotein that we previously isolated from the blood plasma of the pufferfish Takifugu pardalis; this protein was also detected in seven species of the genus Takifugu.
Keiichi Konoki +2 more
exaly +5 more sources
Tetrodotoxins in Ribbon Worms Cephalothrix cf. simula and Kulikovia alborostrata from Peter the Great Bay, Sea of Japan [PDF]
Toxins, 2022 Tetrodotoxin, an extremely potent low-molecular-weight neurotoxin, and its analogues (TTXs) are widely distributed in aquatic and terrestrial ecosystems. Most investigations concerning TTXs have been conducted mainly on puffer fish, octopus, and mollusks,
Anna E. Vlasenko, Timur Yu. Magarlamov
doaj +2 more sources
New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas [PDF]
Marine Drugs, 2023 Tetrodotoxin (TTX) and its analogues are naturally occurring toxins historically responsible for human poisoning fatalities in Eastern Asia. It is typically linked to the consumption of pufferfish and, to a lesser extent, marine gastropods and crabs.
Sandra Lage +3 more
doaj +2 more sources