Results 11 to 20 of about 1,690 (135)

Assessing the Toxicity of Lagocephalus sceleratus Pufferfish from the Southeastern Aegean Sea and the Relationship of Tetrodotoxin with Gonadal Hormones [PDF]

Marine Drugs, 2023
Given the dramatic increase in the L. sceleratus population in the southeastern Aegean Sea, there is growing interest in assessing the toxicity of this pufferfish and the factors controlling its tetrodotoxin (TTX) content.
Thekla I. Anastasiou, Eirini Kagiampaki, Gerasimos Kondylatos, Anastasios Tselepides, Panagiota Peristeraki, Manolis Mandalakis   +5 more
doaj   +2 more sources

Does Ocean Sunfish Mola spp. (Tetraodontiformes: Molidae) Represent a Risk for Tetrodotoxin Poisoning in the Portuguese Coast? [PDF]

Marine Drugs, 2022
Tetrodotoxin (TTX) is a potent neurotoxin naturally occurring in terrestrial and marine organisms such as pufferfish. Due to the risk of TTX poisoning, fish of Tetraodontidae family and other puffer-related species must not be placed in the EU markets ...
Miguel Baptista, Ana Catarina Braga, Rui Rosa, Pedro Reis Costa   +3 more
doaj   +2 more sources

Analytical Method Optimization of Tetrodotoxin and Its Contamination in Gastropods [PDF]

Foods, 2023
Tetrodotoxin (TTX) is an extremely potent marine biotoxin. An analytical method was developed for both trace contamination and extremely high levels of TTX in gastropods by liquid chromatography-tandem mass spectrometry (LC-MS/MS) with clean-up of cation
Jian-Long Han, Lei Zhang, Ping-Ping Zhou, Jiao-Jiao Xu, Xiao-Dong Pan, Pei Cao, Xiao-Min Xu   +6 more
doaj   +2 more sources

Identification of Deoxy- and <i>epi</i>-Tetrodotoxin Analogues from the Newt <i>Cynops ensicauda popei</i> Suggests Stepwise Oxidation in Terrestrial Tetrodotoxin Biosynthesis. [PDF]

J Nat Prod
Tetrodotoxin (TTX, 1) is a potent neurotoxin that selectively blocks voltage-gated sodium channels and occurs in various marine and terrestrial organisms, yet its biosynthetic pathway remains unresolved. In this study, five deoxy-type TTX analogues were identified from the toxic newt Cynops ensicauda popei.
Horie S, Hanifin CT, Cho Y, Konoki K, Yotsu-Yamashita M, Kudo Y.   +5 more
europepmc   +3 more sources

Toxicity Profile of the Oceanic Pufferfish Lagocephalus lagocephalus in the Eastern Atlantic Area [PDF]

Marine Drugs
In recent years, the pufferfish Lagocephalus lagocephalus has been recorded with unusual frequency in coastal areas of the Canary Islands. The most notable episodes occurred in March and November 2017, when numerous shoals were observed along the coasts ...
Nathália Nocchi, Álvaro Santana-Mayor, Adrián Conde-Díaz, Víctor Hernández-Lopez, Adriana Rodríguez Hernández, Alberto Brito, Ana R. Díaz-Marrero, José J. Fernández   +7 more
doaj   +2 more sources

Development of an Automated Cell-Based Assay for the Detection of the Functional Activity of Saxitoxin [PDF]

Toxins
Saxitoxin (STX) is one of the most potent natural neurotoxins known and is the only marine toxin to be declared a chemical weapon. In both marine and freshwater systems filter feeding organisms can accumulate saxitoxin and human consumption of toxin ...
Rachel Whiting, Isobel Picken, Grace Howells, A. Christopher Green, Chris Elliott, Graeme C. Clark   +5 more
doaj   +2 more sources

Cost-Effective and Rapid Detection of Tetrodotoxin Using Indium Tin Oxide Electrodes via In Vitro Electrophysiology and Electrochemistry [PDF]

Toxins
The real-time, cost-effective detection of marine toxins like tetrodotoxin (TTX) remains a significant challenge for the scientific community. Traditional methods, including cell-based assays (CBAs), high-performance liquid chromatography (HPLC), and ...
Naga Adithya Chandra Pandurangi, Manel M. Santafe, Angels Tudo, Nagihan Ozsoy, Fransesc X. Sureda, Mark L. Dallas, Ioanis Katakis   +6 more
doaj   +2 more sources

Levels and Profile of Tetrodotoxins in Spawning Cephalothrix mokievskii (Palaeonemertea, Nemertea): Assessing the Potential Toxic Pressure on Marine Ecosystems [PDF]

Toxins
The ribbon worms of the closely related species Cephalothrix simula, Cephalothrix cf. simula, and Cephalothrix mokievskii, representing the C.
Grigorii V. Malykin, Peter V. Velansky, Timur Yu. Magarlamov   +2 more
doaj   +2 more sources

Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection

Toxins, 2014
Tetrodotoxin (TTX) is a naturally occurring toxin that has been responsible for human intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated puffer fish which are a culinary delicacy, especially in Japan.
Alan O'Riordan, Ambrose Furey, Mary Lehane   +2 more
exaly   +3 more sources

Risks for public health related to the presence of tetrodotoxin (TTX) and TTX analogues in marine bivalves and gastropods

EFSA Journal, 2017
Tetrodotoxin (TTX) and its analogues are produced by marine bacteria and have been detected in marine bivalves and gastropods from European waters. The European Commission asked EFSA for a scientific opinion on the risks to public health related to the ...
EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P. Oswald, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Nathalie Arnich, Diane Benford, Luis Botana, Barbara Viviani, Davide Arcella, Marco Binaglia, Zsuzsanna Horvath, Hans Steinkellner, Mathijs vanManen, Annette Petersen   +30 more
doaj   +6 more sources