Results 21 to 30 of about 4,671 (208)

A Stereocontrolled Synthesis of (+)-Saxitoxin [PDF]

Journal of the American Chemical Society, 2011
A concise stereoselective total synthesis of (+)-saxitoxin is described. A silver(I)-initiated hydroamination cascade constructs the bicyclic guanidinium ion core from a alkynyl bisguanidine. This sequence creates two C-N bonds, one C-O bond, and three rings and forms a single stereoisomer in a single synthetic transformation.
Vasudev R, Bhonde, Ryan E, Looper
openaire   +2 more sources

Paralytic Shellfish Toxins of Pyrodinium bahamense (Dinophyceae) in the Southeastern Gulf of Mexico

Toxins, 2022
In September and November 2016, eight marine sampling sites along the coast of the southeastern Gulf of Mexico were monitored for the presence of lipophilic and hydrophilic toxins.
Erick J. Núñez-Vázquez, Carlos A. Poot-Delgado, Andrew D. Turner, Francisco E. Hernández-Sandoval, Yuri B. Okolodkov, Leyberth J. Fernández-Herrera, José J. Bustillos-Guzmán   +6 more
doaj   +1 more source

Gymnodinium catenatum Paralytic Shellfish Toxin Production and Photobiological Responses under Marine Heat Waves

Toxins, 2023
Marine heatwaves (MHWs) have doubled in frequency since the 1980s and are projected to be exacerbated during this century. MHWs have been shown to trigger harmful algal blooms (HABs), with severe consequences to marine life and human populations.
Vanessa M. Lopes, Mélanie Court, Martim Costa Seco, Francisco O. Borges, Bernardo Vicente, Sandra Lage, Ana Catarina Braga, Bernardo Duarte, Catarina Frazão Santos, Ana Amorim, Pedro Reis Costa, Rui Rosa   +11 more
doaj   +1 more source

A putative gene cluster from a Lyngbya wollei bloom that encodes paralytic shellfish toxin biosynthesis.

PLoS ONE, 2011
Saxitoxin and its analogs cause the paralytic shellfish-poisoning syndrome, adversely affecting human health and coastal shellfish industries worldwide.
Troco K Mihali, Wayne W Carmichael, Brett A Neilan   +2 more
doaj   +1 more source

A Novel SELEX Based on Immobilizing Libraries Enables Screening of Saxitoxin Aptamers for BLI Aptasensor Applications

Toxins, 2022
Saxitoxin (STX) is one of the potent marine biotoxins that has high rate of lethality. However, there are no effective treatments at present, and the existing detection methods need to be further explored because of ethical problems or technical ...
Rong Zhou, Yun Gao, Chengfang Yang, Xiaojuan Zhang, Bo Hu, Luming Zhao, Han Guo, Mingjuan Sun, Lianghua Wang, Binghua Jiao   +9 more
doaj   +1 more source

Amplification of genes associated with saxitoxin biosynthesis in Bacteria associated with pyrodinium Bahamense var. Compressum using Primers designed from other Saxitoxin-producing organisms [PDF]

, 2023
Pyrodinium bahamense var. compressum, the primary producer of saxitoxin (STX) in tropical water, poses a palpable threat to public health and safety. Seafood and aquaculture products contaminated with lethal concentrations of the principal neurotoxin ...
Sylvia Yahumin, Grace Joy Wei Lie Chin, Kenneth Francis Rodrigues   +2 more
core   +1 more source

Changing Trends in Paralytic Shellfish Poisonings Reflect Increasing Sea Surface Temperatures and Practices of Indigenous and Recreational Harvesters in British Columbia, Canada

Marine Drugs, 2021
Paralytic shellfish poisoning (PSP) occurs when shellfish contaminated with saxitoxin or equivalent paralytic shellfish toxins (PSTs) are ingested. In British Columbia, Canada, documented poisonings are increasing in frequency based on 62 investigations ...
Lorraine McIntyre, Aroha Miller, Tom Kosatsky   +2 more
doaj   +1 more source

Lethal paralytic shellfish poisoning from consumption of green mussel broth, Western Samar, Philippines, August 2013

Western Pacific Surveillance and Response, 2015
Background: In July 2013, the Philippines’ Event-Based Surveillance & Response Unit received a paralytic shellfish poisoning (PSP) report from Tarangnan, Western Samar.
Paola Katrina Ching, Ruth Alma Ramos, Vikki Carr de los Reyes, Ma Nemia Sucaldito, Enrique Tayag   +4 more
doaj   +1 more source

The Influence of the Toxin-Producing Dinoflagellate, Alexandrium catenella (1119/27), on the Survival and Reproduction of the Marine Copepod, Acartia tonsa, During Prolonged Exposure

Frontiers in Marine Science, 2021
Copepods can feed on, and may regulate, the blooms of harmful algae (HA), and may also facilitate dinoflagellate blooms by inducing toxin production and through selective grazing.
Ali H. Abdulhussain, Ali H. Abdulhussain, Ali H. Abdulhussain, Kathryn B. Cook, Andrew D. Turner, Adam M. Lewis, Thomas S. Bibby, Daniel J. Mayor   +7 more
doaj   +1 more source

Integrating scFv into xMAP Assays for the Detection of Marine Toxins

Toxins, 2016
Marine toxins, such as saxitoxin and domoic acid are associated with algae blooms and can bioaccumulate in shell fish which present both health and economic concerns.
Lisa C. Shriver-Lake, Jinny L. Liu, P. Audrey Brozozog Lee, Ellen R. Goldman, Richard Dietrich, Erwin Märtlbauer, George P. Anderson   +6 more
doaj   +1 more source