Results 21 to 30 of about 5,292 (200)
A Stereocontrolled Synthesis of (+)-Saxitoxin [PDF]
Journal of the American Chemical Society, 2011 A concise stereoselective total synthesis of (+)-saxitoxin is described. A silver(I)-initiated hydroamination cascade constructs the bicyclic guanidinium ion core from a alkynyl bisguanidine. This sequence creates two C-N bonds, one C-O bond, and three rings and forms a single stereoisomer in a single synthetic transformation.
Vasudev R, Bhonde, Ryan E, Looper
openaire +2 more sources
Toxins, 2023 Marine heatwaves (MHWs) have doubled in frequency since the 1980s and are projected to be exacerbated during this century. MHWs have been shown to trigger harmful algal blooms (HABs), with severe consequences to marine life and human populations.
Vanessa M. Lopes +11 more
doaj +1 more source
Research progress on extraction and analytical methods for saxitoxin and its congeners
, 2023 Saxitoxin is a potent neurotoxin commonly found in shellfish, produced by dinoflagellate and cyanobacterial blooms in seawater or fresh water. This review dissects the conventional liquid–liquid extraction (LLE) and solid-phase extraction (SPE) and the ...
Mohamad Zain, Nur Nadhirah +10 more
core +3 more sources
PLoS ONE, 2011 Saxitoxin and its analogs cause the paralytic shellfish-poisoning syndrome, adversely affecting human health and coastal shellfish industries worldwide.
Troco K Mihali +2 more
doaj +1 more source
Production of antibodies and development of highly sensitive formats of enzyme immunoassay for saxitoxin analysis [PDF]
, 2002 In this paper the production of antibodies against saxitoxin (STX) is described, as is the optimization and comparison of two competitive ELISA formats (direct and indirect) for the detection of this toxin.
COLETTA, MASSIMILIANO +7 more
core +2 more sources
Toxins, 2022 Saxitoxin (STX) is one of the potent marine biotoxins that has high rate of lethality. However, there are no effective treatments at present, and the existing detection methods need to be further explored because of ethical problems or technical ...
Rong Zhou +9 more
doaj +1 more source
Western Pacific Surveillance and Response, 2015 Background: In July 2013, the Philippines’ Event-Based Surveillance & Response Unit received a paralytic shellfish poisoning (PSP) report from Tarangnan, Western Samar.
Paola Katrina Ching +4 more
doaj +1 more source
Marine Drugs, 2021 Paralytic shellfish poisoning (PSP) occurs when shellfish contaminated with saxitoxin or equivalent paralytic shellfish toxins (PSTs) are ingested. In British Columbia, Canada, documented poisonings are increasing in frequency based on 62 investigations ...
Lorraine McIntyre +2 more
doaj +1 more source
Frontiers in Marine Science, 2021 Copepods can feed on, and may regulate, the blooms of harmful algae (HA), and may also facilitate dinoflagellate blooms by inducing toxin production and through selective grazing.
Ali H. Abdulhussain +7 more
doaj +1 more source
Integrating scFv into xMAP Assays for the Detection of Marine Toxins
Toxins, 2016 Marine toxins, such as saxitoxin and domoic acid are associated with algae blooms and can bioaccumulate in shell fish which present both health and economic concerns.
Lisa C. Shriver-Lake +6 more
doaj +1 more source