Results 31 to 40 of about 5,815 (271)

Effects of cylindrospermopsin, chlorpyrifos and their combination in a SH-SY5Y cell model concerning developmental neurotoxicity

Ecotoxicology and Environmental Safety, 2023
M.G. Hinojosa, Ylva Johansson, Ángeles Jos, Ana M. Cameán, Anna Forsby   +4 more
openalex   +2 more sources

Validation of a Method for Cylindrospermopsin Determination in Vegetables: Application to Real Samples Such as Lettuce (Lactuca sativa L.) [PDF]

Toxins, 2018
Reports on the occurrence of the cyanobacterial toxin cylindrospermopsin (CYN) have increased worldwide because of CYN toxic effects in humans and animals.
Ana I. Prieto, Remedios Guzmán-Guillén, Leticia Díez-Quijada, Alexandre Campos, Vitor Vasconcelos, Ángeles Jos, Ana M. Cameán   +6 more
doaj   +4 more sources

Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation [PDF]

Toxins (Basel)
Fredy Duque, Ana I. Prieto, Antonio Cascajosa-Lira, Luis Carlos Montenegro Ruíz, Alexandre Campos, Ángeles Jos, Ana M. Cameán   +6 more
openalex   +2 more sources

Subchronic Oral Cylindrospermopsin Exposure Alters the Host Gut Microbiome and Is Associated with Progressive Hepatic Inflammation, Stellate Cell Activation, and Mild Fibrosis in a Preclinical Study

Toxins, 2022
Epidemiological studies have reported a strong association between liver injury and incidences of hepatocellular carcinoma in sections of humans globally.
Punnag Saha, Macayla Upright, Dipro Bose, Subhajit Roy, Ayushi Trivedi, Madhura More, Geoff I. Scott, Bryan W. Brooks, Saurabh Chatterjee   +8 more
doaj   +1 more source

In silico and in vitro evaluation of potential agonistic and antagonistic estrogenic and androgenic activities of pure cyanotoxins, microcystin-LR and cylindrospermopsin

Ecotoxicology and Environmental Safety
Antonio Casas-Rodríguez, Antonio Cascajosa-Lira, María Puerto, Ana M. Cameán, Ángeles Jos   +4 more
openalex   +2 more sources

Genome analysis of Pseudomonas sp. OF001 and Rubrivivax sp. A210 suggests multicopper oxidases catalyze manganese oxidation required for cylindrospermopsin transformation

BMC Genomics, 2021
Background Cylindrospermopsin is a highly persistent cyanobacterial secondary metabolite toxic to humans and other living organisms. Strain OF001 and A210 are manganese-oxidizing bacteria (MOB) able to transform cylindrospermopsin during the oxidation of
Erika Berenice Martínez-Ruiz, Myriel Cooper, Jimena Barrero-Canosa, Mindia A. S. Haryono, Irina Bessarab, Rohan B. H. Williams, Ulrich Szewzyk   +6 more
doaj   +1 more source

Local-scale impacts of water hyacinth on water quality in a hypereutrophic lake

Frontiers in Water, 2023
Increased nutrient concentrations have been linked to water quality impairments across the world. In Lake Victoria, the second largest freshwater lake in the world, decades of eutrophication have challenged water quality management and led to conditions ...
Jessica R. Corman, Amber Roegner, Amber Roegner, Zachary Ogari, Todd R. Miller, Christopher M. Aura   +5 more
doaj   +1 more source

Potential oestrogenic effects (following the OECD test guideline 440) and thyroid dysfunction induced by pure cyanotoxins (microcystin-LR, cylindrospermopsin) in rats

Environmental Research, 2023
Antonio Casas-Rodríguez, Rosario Moyano, Verónica Molina-Hernández, Ana M. Cameán, Ángeles Jos   +4 more
openalex   +2 more sources

Cytotoxicity and Effects on the Synapsis Induced by Pure Cylindrospermopsin in an E17 Embryonic Murine Primary Neuronal Culture in a Concentration- and Time-Dependent Manner

Toxins, 2022
Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Due to its capacity to exert damage at different levels of the organism, it is considered a cytotoxin.
María G. Hinojosa, Ana I. Prieto, Clara Muñoz-Castro, María V. Sánchez-Mico, Javier Vitorica, Ana M. Cameán, Ángeles Jos   +6 more
doaj   +1 more source

Alternative Isolation Protocol for Desulfo and Zwitterionic Cylindrospermopsin Alkaloids and Comparison of Their Toxicity in HepG2 Cells

Molecules, 2020
The term cylindrospermopsins (CYNs) refers to a structurally related class of cyanobacterial metabolites comprised of a tricyclic guanidine group and a hydroxymethyluracil moiety. Most reports in environmental aquatic samples refer to cylindrospermopsin (
Carlos González-Blanco, Felipe Augusto Dörr, Renata Albuquerque, Janice Onuki, Ernani Pinto   +4 more
doaj   +1 more source