Results 101 to 110 of about 5,510 (174)

Initial Genome-Wide Case–Control Study for Genetic Background of Retinal Dysplasia in Czechoslovakian Wolfdog

Veterinary Sciences
Retinal dysplasia is a genetically heterogeneous ocular disorder in dogs, characterized by abnormal retinal development, resulting in a range of visual impairments from mild to complete blindness.
Michal Gábor, Juraj Candrák, Martina Miluchová, Pavol Zubrický, Agnieszka Balická, Alexandra Trbolová   +5 more
doaj   +1 more source

GSPE and cholestyramine induce the hepatic expression of genes regulating bile acid synthesis.

, 2016
Gene expression was analyzed for (A) Cyp7a1, (B) Cyp8b1, (C) Cyp27a1, and (D) Cyp7b1. Statistical differences are shown as: *p≤0.05, ** p≤0.01, ***p≤0.001, **** p≤0.0001.
Rebecca M. Heidker (812199), Marie-Louise Ricketts (812204), Gianella C. Caiozzi (812200)   +2 more
core   +1 more source

Late-onset Cerebrotendinous Xanthomatosis with a Novel Mutation in the CYP27A1 Gene

Late-onset Cerebrotendinous Xanthomatosis with a Novel Mutation in the CYP27A1 Gene
Cerebrotendinous xanthomatosis (CTX) is a rare, autosomal recessive, inborn disruption in bile acid synthesis characterized by severe systemic xanthomas, cataracts and neurological injuries occurring before adolescence without elevation of the serum cholesterol or triglyceride levels.
openaire  

Integrative multi-omics and machine learning reveals the spatial niche distribution and role of CYP27A1⁺TAMs in immunotherapy response in non-small cell lung cancer. [PDF]

Front Immunol
Liu Q, Liu X, Zhang H, Jiang Y, Shi Y, Mu Q, Jing Y, Sun D.   +7 more
europepmc   +1 more source

Regulation of CYP enzymes in steroidogenesis with particular focus on cholesterol metabolism and vitamin D-related processes

, 2009
CYP27A1 is an enzyme essential for cholesterol homeostasis and is considered an anti-atherogenic enzyme. CYP27A1 is required in bile acid biosynthesis and participates in oxysterol formation, cholesterol transport and cholesterol elimination (Fig 1 ...
Lundqvist, Johan,, Wikvall, Kjell,, Norlin, Maria,, Ellfolk, Maria,, Tang, Wanjin,   +4 more
core  

Decoding lactylation in neuropathic pain: Immune cell infiltration patterns and machine learning-identified candidate biomarkers. [PDF]

Medicine (Baltimore)
Wu W, Yang D.
europepmc   +1 more source

Influence of farnesoid X receptor (<i>FXR</i>) on lipid metabolism in calf hepatocytes exposed to high fatty acid levels. [PDF]

Front Vet Sci
Jia B, Tian Y, Gao C, Chang Y, Zhang Z, Song Y, Xia C, Qu Y, Yang W.   +8 more
europepmc   +1 more source

Involvement of CYP27A1 in retinal cholesterol metabolism, glia-neuron interactions and retinal integrity : a multi-model approach

Le cholestérol est un lipide présent dans les cellules à travers tout le règne animal. Des invertébrés aux vertébrés, il est un composant clé des membranes cellulaires et un précurseur de molécules bioactives.
Urban, Jeanne
core  

Cerebrotendinous xanthomatosis in Slovak patients - experience with clinical manifestations and diagnostic approaches. [PDF]

Neurogenetics
Ďurina P, Bandura A, Chandoga J, Juhosová M, Repiský M, Jungová P, Roháľová J, Jarásková D, Pohorelská V, Dallemule S, Mattošová S, Brennerová K, Okaľová K, Bohuniczky I, Böhmer D.   +14 more
europepmc   +1 more source

Inhibition of the Primary Bile Acid Synthesis Pathways in SD Rats at Different Altitudes. [PDF]

Animals (Basel)
Ma P, Hu Q, Ma F, Zhang W, Gu H, Wei D, An Z.   +6 more
europepmc   +1 more source