Temporal proteomic profiling of iPSC-derived human liver organoids reveals optimal maturation for drug metabolism and toxicology. [PDF]
Yang S, Hao J, Ooka M, Xia M.
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Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity. [PDF]
Fashe MM +8 more
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Exploring the roles of cytochrome P450 enzymes and their inhibitors in cancers and non-neoplastic human diseases. [PDF]
Lee H, Kwon YJ, Chun YJ.
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Endocrine consequences of antifungal therapy: A missed entity. [PDF]
Thakkar S +6 more
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Electro-encephalographic surrogate measures fail to describe the pharmacodynamic interaction between ketamine and propofol. [PDF]
Mortier, Eric +2 more
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Pharmacokinetics of CYP2C19- and CYP3A4-Metabolized Drugs in Cirrhosis Using a Whole-Body PBPK Approach. [PDF]
Mu R +5 more
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In vitro and clinical data demonstrate negligible risk of drug-drug interactions with opelconazole, a novel inhaled antifungal agent. [PDF]
Cass LMR +7 more
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Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions. [PDF]
Tian DD, Hall SD, Chapman SC, Posada MM.
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Drug Interactions Are Crucial in the Care of Patients on Opioid Substitutional Therapy-A Case Report. [PDF]
Devarapalli SK +3 more
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