Results 191 to 200 of about 56,913 (295)

Invasive Fungal Infections in Heart Transplants: A 10‐Year, Single Centre Retrospective Cohort Study From Subtropical Australia

Transplant Infectious Disease, EarlyView.
In this 10‐year retrospective cohort study of heart transplant recipients in subtropical Australia, we characterize the incidence and microbiological profile of invasive fungal infections, highlighting the underappreciated burden of late‐onset and non‐Aspergillus mold infections and the potential underdiagnosis of polymicrobial disease.
Angus Lane, Karen Hay, John McNamara, Alex Chaudhuri, Andrew Burke, Robert Horvath, Maryam Khorramshahi Bayat, Kanthi Vemuri   +7 more
wiley   +1 more source

Pradefovir mesylate and tenofovir amibufenamide for chronic hepatitis B: a systematic review and pragmatic treatment algorithm. [PDF]

Front Pharmacol
Yang S, Zhan L, Wan Z, Yu X.
europepmc   +1 more source

Serious Adverse Events in Adult ICU Patients: A Substudy of the PATIENCE Cohort

Acta Anaesthesiologica Scandinavica, Volume 71, Issue 1, January 2027.
ABSTRACT Introduction Prokinetic agents are used to enhance upper gastrointestinal motility, but adverse events related to these agents are poorly described. We aimed to provide detailed epidemiological data on predefined serious adverse events (SAEs) in a cohort of adult intensive care unit (ICU) patients with and without prokinetic treatment.
Vera Crone, Morten Hylander Møller, Anders Granholm, Anders Perner, Waleed Alhazzani, Abdulrahman Al‐Fares, Johanna Hästbacka, Marlies Ostermann, Carmen A. Pfortmueller, Ricard Ferrer, Annika Reintam Blaser, Eric Keus, Wojciech Szczeklik, Mette Krag   +13 more
wiley   +1 more source

CYP3A4*17 Allele [PDF]

, 2020
openaire   +1 more source

Comparative Pharmacokinetics of Six Bioactive Constituents From Danggui Jixueteng Decoction in Normal and Myelosuppressive Rats

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT This study compared the pharmacokinetics of six constituents from Danggui Jixueteng Decoction in normal versus carboplatin‐induced myelosuppressive rats. A rapid, sensitive ultra‐high performance liquid chromatography‐tandem mass spectrometry method was developed and validated for simultaneous quantification of six diverse constituents (8‐O ...
Mingxin Guo, Yingjie Liu, Zhiqiang Hu, Xiayu Liu   +3 more
wiley   +1 more source

Correction: Taya et al. Clinical Evaluation Based on a New Approach to Improve the Accuracy of 4β-Hydroxycholesterol Measurement as a Biomarker of CYP3A4 Activity. <i>Molecules</i> 2023, <i>28</i>, 1576. [PDF]

Molecules
Taya Y, Mizunaga M, Nakao S, Jutanom M, Shimizu N, Nomura Y, Nakagawa K.   +6 more
europepmc   +1 more source

Association Between BMI and the Efficacy and Safety of CDK4/6 Inhibitors in HR+/HER2− Advanced Breast Cancer: A Multicenter Retrospective Propensity Score Matched Cohort Study (CAMELIA)

MedComm – Oncology, Volume 5, Issue 4, December 2026.
This multicenter real‐world study showed that higher BMI (≥ 25 kg/m2) was independently associated with improved PFS in patients with HR+/HER2− advanced breast cancer receiving CDK4/6 inhibitors. Safety outcomes were comparable between BMI groups, and the findings were consistent across alternative BMI thresholds, suggesting the potential prognostic ...
Min Tian, Yijia Hua, Qian Liu, Nan Jin, Xinyu Wu, Kun Wang, Min Yan, Tao Sun, Chunfang Hao, Yanxia Zhao, Wei Li, Xiang Huang, Yongmei Yin   +12 more
wiley   +1 more source

Association of Native American, European, and African Ancestry with CYP450 Pharmacogenetics and Metabolic Phenotypes in Admixed Latin American Populations from Ecuador and Nicaragua. [PDF]

Pharmaceuticals (Basel)
de la Cruz CG, Altamirano-Tinoco C, Manóchio C, Villatoro-García JA, de Andrés F, Mata-Martín C, Rodrigues-Soares F, Dorado P, Peñas-LLedó EM, Ramírez-Roa R, Teran E, LLerena A, Ribef-Iberofen Consortium.   +12 more
europepmc   +1 more source

Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Zastaprazan, a potassium‐competitive acid blocker, has been developed as an orally disintegrating tablet (ODT) to improve administration flexibility. This study evaluated the pharmacokinetics and safety of a single 20 mg dose of Zastaprazan ODT administered with or without water compared with the conventional tablet in healthy volunteers.
Hyung‐Gun Kim, Seunghyun Kang, Sunyoung Min, Heejoo Hong, Moonjung Bae   +4 more
wiley   +1 more source

Toxicity and DNA Adduct Formation Reinforce AI-Guided Prediction of Aflatoxin B1 Bioactivation in VERO E6 Cells. [PDF]

Toxins (Basel)
Sangwan B, Okoro U, Atteck I, Jaruga P, Ekenna C, Fasullo M.   +5 more
europepmc   +1 more source