Results 101 to 110 of about 6,219 (293)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Triángulo del neo-desarrollismo en Ecuador
Problemas del Desarrollo, 2016 La tesis neo-desarrollista se centra básicamente en un proceso de transformación socioeconómica endógena, liderado por políticas públicas. Para lograr tales fines se requieren tres estrategias conjuntas: i) fomento de un proyecto nacional; ii ...
James M. Cypher, Yolanda Alfaro
doaj
Comparación entre Bases de Datos Orientadas a Grafo y Relacional basado en el rendimiento
Serie Científica de la Universidad de las Ciencias Informáticas, 2020 Actualmente en cada segundo y minuto en el mundo son generados grandes cantidades de datos que necesitan ser almacenados y procesados, esta información es muy variada en cuanto a la forma de almacenamiento y fuente de procedencia así como son muchos y ...
Royland Rodriguez Reyes
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The mystery of the royal cypher from Läckö castle
, 2018 Uppsats för avläggande av filosofie kandidatexamen i Kulturvård, Konservatorprogrammet 15 hp Institutionen för kulturvård Göteborgs universitet 2018:12A royal cypher from Läckö castle is stored in the Department of conservation at The University of ...
Fingal, Angelica
core
Domain- and Language-Adaptable Natural Language Interface for Property Graphs
ComputersDespite the growing adoption of Property Graph Databases, like Neo4j, interacting with them remains difficult for non-technical users due to the reliance on formal query languages.
Ioannis Tsampos, Emmanouil Marakakis
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source