Results 101 to 110 of about 22,923 (293)

Life Cycle Fluoropolymer Management in Proton Exchange Membrane Electrolysis

open access: yesHydrogen
Concerns over the life cycle impacts of fluoropolymers have led to their inclusion in broad product restriction proposals for per- and poly-fluorinated alkyl substances (PFAS), despite their non-bioavailable properties and low exposure potential in ...
Parikhit Sinha, Sabrine M. Cypher
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Veblen y el origen de la hipótesis del catching-up

open access: yesProblemas del Desarrollo, 2012
La economía del desarrollo se conoce como un fenómeno de la posguerra, no tiene antecedentes. No obstante la contribución de Veblen a la economía del desarrollo ya se había reconocido y diseminado anteriormente.
James M. Cypher
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Towards Persistent Storage and Retrieval of Domain Models using Graph Database Technology

open access: yes, 2016
We employ graph database technology to persistently store and retrieve robot domain models.Comment: Presented at DSLRob 2015 (arXiv:1601 ...
Hochgeschwender, Nico   +2 more
core  

Detecting sequential structure [PDF]

open access: yes, 1995
Programming by demonstration requires detection and analysis of sequential patterns in a user’s input, and the synthesis of an appropriate structural model that can be used for prediction. This paper describes SEQUITUR, a scheme for inducing a structural
Nevill-Manning, Craig G., Witten, Ian H.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Refining Text2Cypher on Small Language Model with Reinforcement Learning Leveraging Semantic Information

open access: yesApplied Sciences
Text2Cypher is a text-to-text task that converts natural language questions into Cypher queries. Recent research by Neo4j on Text2Cypher demonstrates that fine-tuning a baseline language model (a pretrained and instruction-tuned generative model) using a
Quoc-Bao-Huy Tran   +3 more
doaj   +1 more source

Spartan Daily, April 28, 1960 [PDF]

open access: yes, 1960
Volume 47, Issue 116https://scholarworks.sjsu.edu/spartandaily/4032/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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