Results 51 to 60 of about 398,157 (315)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Gaussian filter facilitated deep learning-based architecture for accurate and efficient liver tumor segmentation for radiation therapy

Frontiers in Oncology
PurposeAddressing the challenges of unclear tumor boundaries and the confusion between cysts and tumors in liver tumor segmentation, this study aims to develop an auto-segmentation method utilizing Gaussian filter with the nnUNet architecture to ...
Hongyu Lin, Min Zhao, Lingling Zhu, Xi Pei, Haotian Wu, Lian Zhang, Ying Li   +6 more
doaj   +1 more source

Study of Cystic Neck Swellings Over A Period of 5 Years [PDF]

International Journal of Anatomy Radiology and Surgery, 2015
Background and Aim: The swellings in head neck region are of great clinical significance. The pathology of swellings may vary from cysts, benign tumours and malignancy to metastatic tumours. So, these neck swellings are a great dilemma to surgeon for
Darshan Goyal
doaj   +1 more source

Dense granule protein 3 of Toxoplasma gondii plays a crucial role in the capability of the tissue cysts of the parasite to persist in the presence of anti-cyst CD8+ T cells during the chronic stage of infection

Frontiers in Immunology, 2023
Toxoplasma gondii establishes chronic infection by forming tissue cysts, and this chronic infection is one of the most common parasitic infections in humans.
Rajesh Mani, Mohamed H. Abdelaziz, Eri Ochiai, Qila Sa, Barbara A. Fox, David J. Bzik, Yasuhiro Suzuki   +6 more
doaj   +1 more source

Acromioclavicular joint cyst in ASA 3-4 patients. Whether and how quickly it recurs after aspiration and steroid injection [PDF]

, 2016
We observed the clinical course, in the short-medium term, of patients with voluminous type II acromio-clavicular (AC) joint cyst who underwent aspiration and steroid injection regarded as the only possible treatment to avoid possible skin complications.
Candela, Vittorio, Gumina, Stefano, Passaretti, Daniele   +2 more
core  

A latent ability to persist: differentiation in Toxoplasma gondii [PDF]

, 2018
A critical factor in the transmission and pathogenesis of Toxoplasma gondii is the ability to convert from an acute disease-causing, proliferative stage (tachyzoite), to a chronic, dormant stage (bradyzoite).
Jeffers, Victoria, Kim, Kami, Sullivan, William J., Jr., Tampaki, Zoi   +3 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Should We Report Incidental Low-Density Liver Lesions with Benign Features? A Retrospective Single-Center Analysis of Trauma CT Scans

Journal of Gastrointestinal and Abdominal Radiology, 2021
Background Many incidental liver lesions are benign and require no additional workup. Investigation of such lesions can have a negative impact of both the patient and health care system.
Bob Zhang, Prasanna Ratnakanthan, Maryam Shekarforoush, Warren Clements   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Intracranial neuro-enteric cyst: an illustrative patient and review

The Pan African Medical Journal, 2020
Neuroenteric cysts are embryological remnants. Considered as benign congenital lesion, they can occur in the posterior fossa, along the midline structures.
Hajar Bechri, Mohamed Yassaad Oudrhiri, Meriem Fikri, Abdessamad El Ouahabi   +3 more
doaj   +1 more source