Results 151 to 160 of about 6,537 (217)
Some of the next articles are maybe not open access.
Expert Opinion on Drug Delivery, 2019
Background: Cystic fibrosis (CF) is challenged with pathophysiological barriers for effective airway drug-delivery. Hence, we standardized the therapeutic efficacy of the novel dendrimer-based autophagy-inducing anti-oxidant drug, cysteamine.
Janine Faraj +5 more
semanticscholar +1 more source
Background: Cystic fibrosis (CF) is challenged with pathophysiological barriers for effective airway drug-delivery. Hence, we standardized the therapeutic efficacy of the novel dendrimer-based autophagy-inducing anti-oxidant drug, cysteamine.
Janine Faraj +5 more
semanticscholar +1 more source
Mechanism for the inhibition of transglutaminase 2 by cystamine
Biochemical Pharmacology, 2005Cystamine is neuroprotective in a number of models of neurodegeneration. The therapeutic benefit of cystamine has been attributed, in part, to its inhibition of transglutaminase activity. Cystamine [beta-mercaptoethanolamine (MEA) disulfide] is reduced within cells to MEA which is largely responsible for the in vivo effects of its disulfide precursor ...
Thomas M, Jeitner +4 more
openaire +2 more sources
Bioconjugate Chemistry, 1998
Pneumococcal polysaccharide type 6B, 14, or 23F (35-70 kDa) was activated with cyanogen bromide and modified with cystamine. After reduction of the spacer, the thiol-containing (i.e. cysteamine-modified) polysaccharide obtained was added in a 5-10-fold molar excess to bromoacetylated tetanus toxoid to give thioether-linked polysaccharide-protein ...
de Weers, O +5 more
openaire +3 more sources
Pneumococcal polysaccharide type 6B, 14, or 23F (35-70 kDa) was activated with cyanogen bromide and modified with cystamine. After reduction of the spacer, the thiol-containing (i.e. cysteamine-modified) polysaccharide obtained was added in a 5-10-fold molar excess to bromoacetylated tetanus toxoid to give thioether-linked polysaccharide-protein ...
de Weers, O +5 more
openaire +3 more sources
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1984
1. A method for synthesis of 5-S-cystamine-5,6-dihydrothymine was developed. 2. This compound is stable in neutral and acid solutions but rapidly decomposes according to a first-order reaction at pH 10–12. It was found that decomposition is due to acidbase dissociation of 5-S-cystamine-5,6-dihydrothymine (pK ∼ 11.1) and that the rate of ...
S. A. Grachev +2 more
openaire +1 more source
1. A method for synthesis of 5-S-cystamine-5,6-dihydrothymine was developed. 2. This compound is stable in neutral and acid solutions but rapidly decomposes according to a first-order reaction at pH 10–12. It was found that decomposition is due to acidbase dissociation of 5-S-cystamine-5,6-dihydrothymine (pK ∼ 11.1) and that the rate of ...
S. A. Grachev +2 more
openaire +1 more source
Journal of Dispersion Science and Technology, 2018
Monoolein (MO) cubic phase including alginate and cystamine in its water channel controlled the release of epidermal growth factor (EGF) by responding to changes in pH value and the reductive conditions of the release medium.
Tae Hoon Kim +6 more
semanticscholar +1 more source
Monoolein (MO) cubic phase including alginate and cystamine in its water channel controlled the release of epidermal growth factor (EGF) by responding to changes in pH value and the reductive conditions of the release medium.
Tae Hoon Kim +6 more
semanticscholar +1 more source
The radiation chemistry of cystamine sulphate
Journal of the Chemical Society B: Physical Organic, 1967Irradiation of aqueous cystamine solutions with X-rays (230 kV; 15 mA), in the presence of oxygen, results in the formation of taurine, hydrogen peroxide, and traces of hydrogen sulphide. When oxygen is removed from the solution, hydrogen sulphide formation increases noticeably, while yields of taurine and peroxide both decrease.
G. G. Jayson +2 more
openaire +1 more source
ChemInform Abstract: Synthesis of Cystamine.
ChemInform, 1991AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A. D. BULAT +4 more
openaire +1 more source
Electron Reactions in γ-Irradiated Thymidine and Cystamine
Nature, 1970ALTHOUGH the technique of electron spin resonance (ESR) has been useful in the identification of some of the secondary radical species formed in γ-irradiated DNA and proteins, difficulties have been experienced in the interpretation of the spectra of the primary radiolytic products.
A D, Lenherr, M G, Ormerod
openaire +2 more sources
On the Radioprotective Action of Cystamine at the Yeast Cell Membrane
Radiation Research, 1968STUART, BRUCE 0., AND STANNARD, J. N. On the Radioprotective Action of Cystamine at the Yeast Cell Membrane. Radiation Res. 34, 459-472 (1968). The dithiol, cystamine, affords marked protection against the effects of X-irradiation on potassium leakage from baker's yeast cells.
B O, Stuart, J N, Stannard
openaire +2 more sources