Results 151 to 160 of about 4,936 (212)
Suppressed Autoxidation, Enhanced Antioxidant Activity, and Improved Cytocompatibility of Epigallocatechin Gallate via Alginate Site-Specific Conjugation with Tunable Substitution Degree. [PDF]
Int J Mol SciYongvongsoontorn N +4 more
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Experimental and Molecular Medicine, 2004 The treatment of cystamine, a transglutaminase (TGase) inhibitor, has beneficial effects in several diseases including CAG-expansion disorders and cataract.
Chai-Wan Kim, In-Gyu Kim, Sung-Yup Cho
exaly +2 more sources
Redox-responsive alginate microsphere containing cystamine
Journal of Biomaterials Science, Polymer Edition, 2016 Redox-responsive microspheres were prepared by solidifying the alginate- and cystamine-containing water droplets of O/W emulsion using calcium ion. Emulsions were prepared using alginate/cystamine mixture solution whose the carboxylic group/the amino ...
Jin-Chul Kim
exaly +2 more sources
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International Journal of Peptide and Protein Research, 1986
A cystamine‐enkephalin dimer, containing two molecules of [D‐Ala2, Leu5] enkephalin cross‐linked at theCOOH‐terminal leucine residue with cystamine, (NH2‐CH2‐CH2‐S‐)2, has been synthesized in order to examine directly the dimerization effect of an enkephalin molecule on the opiate receptor interactions. In a comparison of potencies against [3H]‐[D‐Ala2,
MICHIO KONDO +3 more
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A cystamine‐enkephalin dimer, containing two molecules of [D‐Ala2, Leu5] enkephalin cross‐linked at theCOOH‐terminal leucine residue with cystamine, (NH2‐CH2‐CH2‐S‐)2, has been synthesized in order to examine directly the dimerization effect of an enkephalin molecule on the opiate receptor interactions. In a comparison of potencies against [3H]‐[D‐Ala2,
MICHIO KONDO +3 more
openaire +2 more sources
The ability of cystamine to bind DNA
Amino Acids, 2002The DNA-binding properties of cystamine compared with natural occurring polyamines have been studied in vitro by means of ethidium bromide displacement assays, studies of DNA thermal stability and analyses of DNA-B/DNA-A transition. While the first two methods did not put in evidence any peculiar property in the binding capability of cystamine, CD ...
ALLEGRA, Paola +3 more
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1987
Publisher Summary This chapter discusses about cysteamine and cystamine. Cysteamine (2-aminoethanethiol) is formed in mammalian tissues by the enzymatic hydrolysis of pantetheine, and has the role in the biosynthesis of hypotaurine. Cysteamine has been used therapeutically to treat cystinosis and sickle cell anemia, and has been used as a protective ...
M W, Duffel, D J, Logan, D M, Ziegler
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Publisher Summary This chapter discusses about cysteamine and cystamine. Cysteamine (2-aminoethanethiol) is formed in mammalian tissues by the enzymatic hydrolysis of pantetheine, and has the role in the biosynthesis of hypotaurine. Cysteamine has been used therapeutically to treat cystinosis and sickle cell anemia, and has been used as a protective ...
M W, Duffel, D J, Logan, D M, Ziegler
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Interaction of Cystamine and Cystamine Derivatives with Nucleic Acids and Nucleoproteins
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1965SummaryThe disulphides–cystamine, bis (2-guanidoethyl) disulphide (GED), dimethylcystamine, tetramethylcystamine, tetraethyl cystamine, cystine dimethyl ester and cystine diethyl ester–have been shown to interact with and become reversibly bound to calf thymus DNA, E. ccli RNA, and to calf-thymus and rat-liver nucleoproteins.
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A Trial of Cystamine in Radiation Sickness
The British Journal of Radiology, 1960A trial was made of the radioprotective substance, Cystamine, in radiation sickness. It did not prove more effective than lactose.
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Cystamine modulation of galactosamine-induced hepatotoxicity
Toxicology and Applied Pharmacology, 1984The ability of cystamine treatment to protect against galactosamine-induced hepatic necrosis was investigated. Reduced hepatotoxicity was observed following galactosamine hydrochloride (400 mg/kg, ip) in male Sprague-Dawley rats that received cystamine dihydrochloride (300 mg/kg, po) 30 min prior to or 2, 4, 6, 8, or 12 hr after galactosamine.
J R, MacDonald +2 more
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The effect of cystamine on gastric secretion in the rat
Agents and Actions, 1979The effects of cystamine on gastric secretion were studied in conscious and anaesthetized rat preparations. In the conscious gastric fistula rat cystamine inhibited the basal acid output but increased pepsin output. This pepsinogogue action was inhibited by both atropine and metiamide.
M E, Parsons +4 more
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