Results 161 to 170 of about 4,936 (212)
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Bioconjugate Chemistry, 1998
Pneumococcal polysaccharide type 6B, 14, or 23F (35-70 kDa) was activated with cyanogen bromide and modified with cystamine. After reduction of the spacer, the thiol-containing (i.e. cysteamine-modified) polysaccharide obtained was added in a 5-10-fold molar excess to bromoacetylated tetanus toxoid to give thioether-linked polysaccharide-protein ...
de Weers, O +5 more
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Pneumococcal polysaccharide type 6B, 14, or 23F (35-70 kDa) was activated with cyanogen bromide and modified with cystamine. After reduction of the spacer, the thiol-containing (i.e. cysteamine-modified) polysaccharide obtained was added in a 5-10-fold molar excess to bromoacetylated tetanus toxoid to give thioether-linked polysaccharide-protein ...
de Weers, O +5 more
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Mechanism for the inhibition of transglutaminase 2 by cystamine
Biochemical Pharmacology, 2005Cystamine is neuroprotective in a number of models of neurodegeneration. The therapeutic benefit of cystamine has been attributed, in part, to its inhibition of transglutaminase activity. Cystamine [beta-mercaptoethanolamine (MEA) disulfide] is reduced within cells to MEA which is largely responsible for the in vivo effects of its disulfide precursor ...
Thomas M, Jeitner +4 more
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The radiation chemistry of cystamine sulphate
Journal of the Chemical Society B: Physical Organic, 1967Irradiation of aqueous cystamine solutions with X-rays (230 kV; 15 mA), in the presence of oxygen, results in the formation of taurine, hydrogen peroxide, and traces of hydrogen sulphide. When oxygen is removed from the solution, hydrogen sulphide formation increases noticeably, while yields of taurine and peroxide both decrease.
G. G. Jayson +2 more
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Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1984
1. A method for synthesis of 5-S-cystamine-5,6-dihydrothymine was developed. 2. This compound is stable in neutral and acid solutions but rapidly decomposes according to a first-order reaction at pH 10–12. It was found that decomposition is due to acidbase dissociation of 5-S-cystamine-5,6-dihydrothymine (pK ∼ 11.1) and that the rate of ...
S. A. Grachev +2 more
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1. A method for synthesis of 5-S-cystamine-5,6-dihydrothymine was developed. 2. This compound is stable in neutral and acid solutions but rapidly decomposes according to a first-order reaction at pH 10–12. It was found that decomposition is due to acidbase dissociation of 5-S-cystamine-5,6-dihydrothymine (pK ∼ 11.1) and that the rate of ...
S. A. Grachev +2 more
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Neuroprotective effects of cystamine in aged parkinsonian mice
Neurobiology of Aging, 2006Accumulating evidence suggests an important role of oxidation in pathologies such as Parkinson's disease. Here, we investigated the effects of cystamine, which has shown neuroprotection in animal models of Huntington's disease, in a parkinsonian mouse generated by the toxin MPTP. Aged mice (16 months of age) were assigned to either a 10 or 50 mg/kg/day
Marie-Eve, Tremblay +5 more
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ChemInform Abstract: Synthesis of Cystamine.
ChemInform, 1991AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A. D. BULAT +4 more
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On the Radioprotective Action of Cystamine at the Yeast Cell Membrane
Radiation Research, 1968STUART, BRUCE 0., AND STANNARD, J. N. On the Radioprotective Action of Cystamine at the Yeast Cell Membrane. Radiation Res. 34, 459-472 (1968). The dithiol, cystamine, affords marked protection against the effects of X-irradiation on potassium leakage from baker's yeast cells.
B O, Stuart, J N, Stannard
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Cystamine bislactamide: a cosmetic allergen
The Lancet, 1998S, Borelli +4 more
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Thiazolinylharnstoff aus Cystamin
Angewandte Chemie, 1951A. Schöberl, M. Kawohl
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